Biosynthesis and biological activities of magnesium hydroxide nanoparticles using Tinospora cordifolia leaf extract.

The synthesis of magnesium hydroxide nanoparticles (Mg(OH) NPs) using plant extracts are known to be a practical, economical, and an environmentally friendly approach. In this work, Mg(OH) NPs were synthesized using aqueous leaf extract of Tinospora cordifolia, a medicinal plant commonly found in India. The synthesized Mg(OH) NPs were characterized using various spectroscopic techniques.

Chitosan/PLA-loaded Magnesium oxide nanocomposite to attenuate oxidative stress, neuroinflammation and neurotoxicity in rat models of Alzheimer's disease.

Alzheimer's disease (AD) is a neurodegenerative disease characterized by amyloid-beta (Aβ) aggregation, neuroinflammation, oxidative stress, and dysfunction in the mitochondria and cholinergic system. In this study, the synthesis of chitosan-polylactic acid-loaded magnesium oxide nanocomposite (CH/PLA/MgONCs) was examined using the green precipitation method. The synthesized CH/PLA/MgONCs were confirmed by using the UV-Vis spectrum, FT-IR, SEM-EDAX, and physical properties.

Facile preparation of biocompatible macroporous chitosan hydrogel by hydrothermal reaction of a mixture of chitosan-succinic acid-urea.

The facile preparation of macroporous, super water absorbing, biocompatible hydrogels of chitosan involving the hydrothermal reaction of a mixture of chitosan (CH), succinic acid (SA) and urea (UR), all of which are sustainable materials, is reported. The structure of the dry CHSAUR was ascertained by CP MAS-SS NMR spectroscopy, Fourier transform infrared (FTIR) spectroscopy, powder x-ray diffraction analysis (PXRD), and thermogravimetric analysis (TGA). The principle role of UR in the synthesis was identified as the source of ammonia, which increased the pH of the acidic chitosan solution with reaction time, leading to the formation of the insoluble hydrogel of chitosan accompanied by the formation of pores of different sizes and volumes.