Use of 2Shape® File in Adaptive Kinematics Influences Post-operative Pain After Single Visit Endodontics in Symptomatic Irreversible Pulpitis: A Double-blinded, Randomized Clinical Trial.

Objective: This double-blinded randomized clinical trial aimed to compare postoperative pain using 2Shape® (TS) in rotary (TSRot) and adaptive (TSAK) kinematics in the maxillary and mandibular molars in patients with symptomatic irreversible pulpitis and symptomatic apical periodontitis following single-visit endodontic treatment.

Methods: Seventy patients were randomly assigned to two groups (TSRot /TSAK), (n=35 each). The preoperative and postoperative pain intensities at various time intervals up to 72h using a Visual-Analogue Scale was noted.

Charge Transfer in n-FeO and p-α-FeO Nanoparticles for Efficient Hydrogen and Oxygen Evolution Reaction.

This study aims to explore the n-FeO and p-α-FeO semiconductor nanoparticles in hydrogen (HER) and oxygen (OER) evolution reactions and a combined full cell electrocatalyst system to electrolyze the water. We have observed a distinct electrocatalytic performance for both HER and OER by tuning the interplay between iron oxidation states Fe and Fe and utilizing phase-transformed iron oxide nanoparticles (NPs). The Fe rich n-FeO NPs exhibited superior HER performance compared to p-α-FeO and Fe(OH) NPs, which is attributed to the enhancement in n-type semiconducting nature under HER potential, facilitating the electron transfer for the reduction in H ions.

Effect of Deep Margin Elevation on the Pulpal and Periodontal Health of Teeth: A Systematic Review.

Objective: To systematically evaluate the clinical performance of deep margin elevation (DME) technique in terms of pulpal and periodontal health of teeth.

Methods And Materials: An exploratory search was performed in PubMed, Scopus, Embase, Web of Science, and Google Scholar up to September 2023 by two authors independently. This systematic review was performed in accordance with Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Systematic Reviews (PRISMA-SR) and registered with PROSPERO-CRD42022382082.

Mechanochemical Pretreated MAX (MAX) Phase to Synthesize 2D-TiCT MXene Sheets for High-Performance Supercapacitors.

Two-dimensional (2D) MXenes sheet-like micro-structures have attracted attention as an effective electrochemical energy storage material due to their efficient electrolyte/cation interfacial charge transports inside the 2D sheets which results in ultrahigh rate capability and high volumetric capacitance. In this article, TiCT MXene is prepared by a combination of ball milling and chemical etching from TiAlC powder. The effects of ball milling and etching duration on the physiochemical properties are also explored, as well as the electrochemical performance of as-prepared TiC MXene.

Electrocatalytic Oxygen Reduction Reaction of Graphene Oxide and Metal-Free Graphene in an Alkaline Medium.

Graphene is a well-known two-dimensional material with a large surface area and is used for numerous applications in a variety of fields. Metal-free carbon materials such as graphene-based materials are widely used as an electrocatalyst for oxygen reduction reactions (ORRs). Recently, more attention has been paid to developing metal-free graphenes doped with heteroatoms such as N, S, and P as efficient electrocatalysts for ORR.

Exploring the Potentiality of Native Actinobacteria to Combat the Chilli Fruit Rot Pathogens under Post-Harvest Pathosystem.

Chilli is an universal spice cum solanaceous vegetable crop rich in vitamin A, vitamin C, capsaicin and capsanthin. Its cultivation is highly threatened by fruit rot disease which cause yield loss as high as 80-100% under congenial environment conditions. Currently actinobacteria are considered as eco-friendly alternatives to synthetic fungicides at pre and post-harvest pathosystems.

Djurleite Copper Sulfide-Coupled Cobalt Sulfide Interface for a Stable and Efficient Electrocatalyst.

Transition metal sulfides (TMS) exhibit proliferated edge sites, facile electrode kinetics, and improved intrinsic electrical conductivity, which demand low potential requirements for total water splitting application. Here, we have propounded copper sulfide-coupled cobalt sulfide nanosheets grown on 3D nickel as an electrocatalyst for hydrogen (HER) and oxygen evolution (OER) reactions. The formation of djurleite copper sulfide with a Cu vacancy enables faster H ion transport and shows improved HER activity with a remarkably lower overpotential of 164 mV at 10 mA/cm, whereas cobalt-incorporated copper sulfide undergoes cation exchange during synthesis and shows elevated OER activity with a lower overpotential of 240 mV at 10 mA/cm for the OER.

Transition metal oxy/hydroxides functionalized flexible halloysite nanotubes for hydrogen evolution reaction.

The hierarchical halloysite nanotubes (HNT) have alumina containing positive Al-OH groups on its inner surface and silica-containing negative siloxane groups of Si-O-Si on its outer surface. The silicate laminate consists of silicon-oxygen at tetrahedral sites and aluminum-oxygen at octahedral sites. Since HNT has an abundant hydroxyl group on the surface with exceptional cation/anion exchange capacity, the surface-functionalized HNT could boost electrocatalytic activity.

High-performance flexible transparent micro-supercapacitors from nanocomposite electrodes encapsulated with solution processed MoS nanosheets.

Two-dimensional molybdenum disulfide (MoS) nanosheets have emerged as a promising material for transparent, flexible micro-supercapacitors, but their use in electrodes is hindered by their poor electrical conductivity and cycling stability because of restacking. In this paper, we report a novel electrode architecture to exploit electrochemical activity of MoS nanosheets. Electrochemically exfoliated MoS dispersion was spin coated on mesh-like silver networks encapsulated with a flexible conducting film exhibiting a pseudocapacitive behavior.

Electrodeposited Trimetallic NiFeW Hydroxide Electrocatalysts for Efficient Water Oxidation.

Tungsten-doped Ni-Fe hydroxides fabricated on a three-dimensional nickel foam through cathodic electrodeposition are proposed as effective oxygen evolution reaction (OER) catalysts for alkaline water oxidation. Incorporating an adequate amount of W into Ni-Fe hydroxides modulates the electronic structure by changing the local environment of Ni and Fe and create oxygen vacancies, resulting in abundant active sites for the OER. The optimized electrocatalyst, with a substantial number of catalytic sites, is found to outperform the well-established 20 wt% Ir/C electrocatalyst.

Extracellular DNA (eDNA): Neglected and Potential Sources of Antibiotic Resistant Genes (ARGs) in the Aquatic Environments.

Over the past decades, the rising antibiotic resistance bacteria (ARB) are continuing to emerge as a global threat due to potential public health risk. Rapidly evolving antibiotic resistance and its persistence in the environment, have underpinned the need for more studies to identify the possible sources and limit the spread. In this context, not commonly studied and a neglected genetic material called extracellular DNA (eDNA) is gaining increased attention as it can be one of the significant drivers for transmission of extracellular ARGS (eARGs) via horizontal gene transfer (HGT) to competent environmental bacteria and diverse sources of antibiotic-resistance genes (ARGs) in the environment.

Enhancing ORR/OER active sites through lattice distortion of Fe-enriched FeNi intermetallic nanoparticles doped N-doped carbon for high-performance rechargeable Zn-air battery.

Low-cost, high-activity, non-precious metal electrocatalysts are needed to enhance the bifunctional oxygen activities of rechargeable Zn-Air batteries. In this study, a Fe-enriched FeNi inter-metallic nanoparticle/nitrogen-doped carbon (Fe-enriched-FeNi/NC) electrocatalyst was designed and prepared using a facile method based on plasma engineering. The excess Fe-ions in the Fe-enriched FeNi nanoparticles led to a high degree of lattice distortion that produced abundant oxygen-active sites.

Cation intercalated one-dimensional manganese hydroxide nanorods and hierarchical mesoporous activated carbon nanosheets with ultrahigh capacitance retention asymmetric supercapacitors.

We have reported the electrochemical performance of K ion doped Mn(OH) and MnO nanorods as a positive electrode and a highly porous activated carbon nanosheet (AC) made from Prosopis Juliflora as negative electrode asymmetric supercapacitor (ASC) with high rate capability and capacity retention. The cation K doped Mn(OH) and MnO nanorods with large tunnel sizes allow the electrolyte to penetrate through a well-defined pathway and hence benefits from the intercalation pseudocapacitance and surface redox reactions. As a result, they exhibit good electrochemical performance in neutral aqueous electrolytes.

Self-assembled 3D hierarchical MnCO/NiFe layered double hydroxides as a superior electrocatalysts for the oxygen evolution reactions.

Developing cost-effective and efficient oxygen evolution reaction (OER) electrocatalyst is highly essential for energy-conversion technologies. A self-assembled NiFe-layered double hydroxide (LDH)@MnCO heterostructure prepared on Ni foam using a successive hydrothermal strategy shows notable catalytic activity toward the OER with a small overpotential of 275 mV to drive a geometrical current density of 10 mA cm under alkaline conditions with remarkable stability for 15 h, outperforming IrO/C electrocatalyst (350 mV@10 mA cm). The hierarchical NiFe-LDH@MnCO heterostructure possess more exposed active sites, enhanced conductivity and superior interfacial coupling effect makes them an ideal candidate for OER electrocatalyst.

Environmental Prevalence of Carbapenem Resistance Enterobacteriaceae (CRE) in a Tropical Ecosystem in India: Human Health Perspectives and Future Directives.

In the past few decades, infectious diseases have become increasingly challenging to treat, which is explained by the growing number of antibiotic-resistant bacteria. Notably, carbapenem-resistant Enterobacteriaceae (CRE) infections at global level attribute a vast, dangerous clinical threat. In most cases, there are enormous difficulties for CRE infection except a few last resort toxic drugs such as tigecycline and colistin (polymyxin E).

Extreme Environment : Potential Sources for New Antibacterial and Anticancer Drug Leads?

Antimicrobial resistance (AR) is recognized as one of the greatest threats to public health and in global concern. Consequently, the increased morbidity and mortality, which are associated with multidrug resistance bacteria, urgently require the discovery of novel and more efficient drugs. Conversely, cancer is a growing complex human disease that demands new drugs with no or fewer side effects.

Phylogenetic insight of Nonribosomal peptide synthetases (NRPS) Adenylate domain in Antibacterial potential Streptomyces BDUSMP 02 isolated from Pitchavaram Mangrove.

Identification of gene clusters in Streptomyces holds promise for the discovery of regulatory pathways linked to bioactive metabolites. We isolated a broad-spectrum antibacterial potential Streptomyces sp BDUSMP 02 from mangrove sediment. We further found a distinct of phylogeny pattern for NRPS A-domain in the Streptomyces sp BDUSMP 02.

Role of photostriction and photothemal effects in photon induced deflection of Si microcantilevers.

Laser beam (He-Ne - 6328 A) induced deflection in uncoated, Au, and Al coated Si microcantilevers (MCs) of various dimensions was studied, using an AFM head, to examine the induced stress contribution from photothermal and photostriction phenomenon. The laser beam was made to incident sequentially on front and back surfaces of the MC, by flipping it, and results were compared in terms of deflection magnitude, direction of bending and response time. In case of uncoated MCs, it was observed that the induced deflection was always in the direction of the incident laser beam with a fast response.

Revealing the Self-Degradation Mechanisms in Methylammonium Lead Iodide Perovskites in Dark and Vacuum.

Organic-inorganic lead halide perovskite phases segregate (and their structures degrade) under illumination, exhibiting a poor stability with hysteresis and producing halide accumulation at the surface.In this work, we observed structural and interfacial dissociation in methylammonium lead iodide (CH NH PbI ) perovskites even under dark and vacuum conditions. Here, we investigate the origin and consequences of self-degradation in CH NH PbI perovskites stored in the dark under vacuum.

Inhibition of Redox Behaviors in Hierarchically Structured Manganese Cobalt Phosphate Supercapacitor Performance by Surface Trivalent Cations.

The stability and performance of supercapacitor devices are limited by the diffusion-controlled redox process occurring at materials' surfaces. Phosphate-based metal oxides could be effectively used as pseudocapacitors because of their polar nature. However, electrochemical energy storage applications of Mn-Co-based phosphate materials and their related kinetics studies have been rarely reported.

Influence of solvents in the preparation of cobalt sulfide for supercapacitors.

In this study, cobalt sulfide (CoS) electrodes are synthesized using various solvents such as water, ethanol and a combination of the two via a facile chemical bath deposition method on Ni foam. The crystalline nature, chemical states and surface morphology of the prepared CoS nanoparticles are characterized using X-ray diffraction, X-ray photoelectron spectroscopy, scanning electron microscopy and transition electron microscopy. The electrochemical properties of CoS electrodes are also evaluated using cyclic voltammetry, galvanostatic charge-discharge and electrochemical impedance spectroscopy.

Occurrence of Antibiotic Resistance Genes and Bacterial Markers in a Tropical River Receiving Hospital and Urban Wastewaters.

The occurrence of emerging biological contaminants including antibiotic resistance genes (ARGs) and Faecal Indicator Bacteria (FIB) is still little investigated in developing countries under tropical conditions. In this study, the total bacterial load, the abundance of FIB (E. coli and Enterococcus spp.

Phase transition kinetics and surface binding states of methylammonium lead iodide perovskite.

We have presented a detailed analysis of the phase transition kinetics and binding energy states of solution processed methylammonium lead iodide (MAPbI3) thin films prepared at ambient conditions and annealed at different elevated temperatures. It is the processing temperature and environmental conditions that predominantly control the crystal structure and surface morphology of MAPbI3 thin films. The structural transformation from tetragonal to cubic occurs at 60 °C with a 30 minute annealing time while the 10 minute annealed films posses a tetragonal crystal structure.

BMP-7 Induces Adult Human Pancreatic Exocrine-to-Endocrine Conversion.

The exocrine pancreas can give rise to endocrine insulin-producing cells upon ectopic expression of key transcription factors. However, the need for genetic manipulation remains a translational hurdle for diabetes therapy. Here we report the conversion of adult human nonendocrine pancreatic tissue into endocrine cell types by exposure to bone morphogenetic protein 7.

Accumulation of clinically relevant antibiotic-resistance genes, bacterial load, and metals in freshwater lake sediments in Central Europe.

Wastewater treatment plants (WWTP) receive the effluents from various sources (communities, industrial, and hospital effluents) and are recognized as reservoir for antibiotic-resistance genes (ARGs) that are associated with clinical pathogens. The aquatic environment is considered a hot-spot for horizontal gene transfer, and lake sediments offer the opportunity for reconstructing the pollution history and evaluating the impacts. In this context, variation with depth and time of the total bacterial load, the abundance of faecal indicator bacteria (FIB; E.