Histological Evaluation of Single and Double-visit Direct Pulp Capping with Different Materials on Sound Human Premolars: A Randomized Controlled Clinical Trial.

Introduction: The aim of this study was to evaluate the clinical and histological status of the pulp in sound human premolars after direct pulp capping (DPC) with four different DPC methods/materials.

Methods And Materials: This study was conducted on eight volunteers who had to extract four first premolars due to orthodontic treatment. Subsequent to tooth isolation, standardized class I occlusal cavities were prepared and the buccal pulp horns were exposed.

Granular cell type of a unicystic ameloblastoma: An unusual case and review of the literature.

Ameloblastomas are locally invasive tumors of odontogenic epithelial origin. They have been categorized broadly into three biologic variants: solid, cystic (unicystic) and peripheral, of which only 13% of all cases are unicystic. Although rare in unicystic or cystic ameloblastoma, granular cell change in ameloblastoma is a recognized phenomenon.

The effect of celecoxib on orthodontic tooth movement and root resorption in rat.

Objective: Inhibition of prostaglandin (PGs) production leads to decrease in orthodontic tooth movement (OTM). It is not known whether inhibition of cyclooxygenase-1 (COX-1) or cyclooxygenase-2 (COX-2) is the key mechanism for this effect. In this study, the effect of celecoxib, a highly-selective COX-2 inhibitor, was investigated on OTM in rats.

Microleakage of Er:YAG laser and dental bur prepared cavities in primary teeth restored with different adhesive restorative materials.

The purpose of this study was to evaluate and compare the effect of erbium:yttrium-aluminum-garnet (Er:YAG) laser irradiation and conventional dental bur cavity preparation on in vitro microleakage of class V cavities restored with different adhesive restorative materials and two types of self-etching adhesives in primary teeth. Standard class V cavities were prepared on 80 extracted primary, and the teeth were randomly divided into eight subgroups prepared either by dental bur or Er:YAG laser irradiation and then restored with self-cured glass ionomer (GI), resin-modified glass ionomer (RMGI), resin composite and Clearfil SE Bond (two-step self-etching adhesive), and resin composite and Clearfil S3 Bond (one-step self-etching adhesive). Restorations were finished and stored in distilled water at 37 °C for 24 h and then subjected to thermocycling.

Endoglin (CD105) positive microvessel density and its relationship with lymph node metastasis in squamous cell carcinoma of the tongue.

Background: Neovascularization is an important factor for predicting tumor behavior. Evidence suggests that endoglin (CD105) is a powerful marker of neovascularization and determination of microvessel density in several malignancies, and can be used as an agent to predict lymph node metastasis. However, it is controversial, particularly in head and neck squamous cell carcinoma.

The effect of platelet-rich plasma on healing of palatal donor site following connective tissue harvesting: a pilot study in dogs.

Background: Peri-implant plastic surgery includes soft tissue enhancement by connective tissue grafting. The palatal donor site provides peri-implant keratinized mucosa and soft tissue height. Platelet-rich plasma (PRP) contains growth factors that may enhance early healing.

A comparison of bone reconstruction following application of bone matrix gelatin and autogenous bone grafts to alveolar defects: an animal study.

The aim of this study was to compare the quantity and quality of osseous healing of bone matrix gelatin (BMG) with autogenous bone graft (ABG) in cat models. Osseous defects (5 x 5mm) were made through upper alveolar bone distal to the canines in the left and right quadrants (maxilla) in each of twelve Persian male cats and filled randomly with BMG and ABG. The repair response was examined on days 14, 28, and 56 after surgery (n=4 per bone substitute per time point).

Effect of salivary contamination on microleakage of resin composites placed with a self-etch adhesive in primary teeth: an in vitro study.

Purpose: The purpose of this study was to investigate in vitro the effect of salivary contamination on the microleakage of resin composite restorations placed with a self-etching adhesive in primary teeth.

Methods: Fifty-six extracted primary molars received standardized Class V preparations. The teeth were assigned to 7 groups (n=8): 1-layer and 2-layer application of the self-etching primer (Clearfil SE Bond) with no contamination (groups 1 and 2, respectively); saliva, SE primer, and drying (group 3); SE primer, drying, saliva, and drying (group 4); SE primer, drying, saliva, and rinsing/drying (group 5); SE primer, drying, saliva, drying, SE primer, and drying (group 6); and SE primer, drying, saliva, rinsing/drying, SE primer, and drying (group 7).

Sclerosing stromal tumor of the ovary.

Sclerosing stromal tumors are benign ovarian neoplasms of the sex cord stromal category which occur predominantly in the second and third decades of life. Herein, we report a 26-year-old woman who developed a sclerosing stromal tumor of the ovary with irregular menses but normal hormonal status. She was suspected to have a malignant tumor and underwent bilateral oophorectomy.

Orthodontic tooth movement in cholestatic and cirrhotic rats.

Objective: To investigate whether cirrhosis and cholestasis could influence orthodontic tooth movement.

Design: Basic science, animal experimental study.

Setting: This study was conducted in the Department of Pharmacology, School of Medicine at Tehran University of Medical Sciences in 2007.

Expression of p21WAF in salivary gland mucoepidermoid carcinoma and its relation to histologic grade.

The biologic behavior and factors influencing the development of salivary gland mucoepidermoid carcinoma are not fully understood. Alteration of the cyclin-dependant kinase inhibitor p21(WAF) could cause uncontrolled proliferation leading to cancer. Thirty-five mucoepidermoid carcinomas were graded and immunohistochemically stained for p21(WAF).

Healing of apical periodontitis after endodontic treatment with and without obturation in dogs.

The principle of obturation of the root canal space is generally accepted. This belief has dominated the field of endodontics despite the absence of credible scientific evidence. Little information is available on the possible relationships between endodontic success and obturation of the root canal system.

Bilateral symmetrical lymphangiomas of the gingiva: case report.

Background: Lymphangioma is a benign lesion that is related to proliferation of lymphatic vessels. Lymphangioma of the gingiva is a rare lesion that manifest as a pebbly hyperplasia on gingiva. The purpose of this study is to report a case of bilateral symmetrical lymphangioma of the gingiva.

Immunohistochemical evaluation of p27 (kip1) in pleomorphic adenomas and adenoid cystic carcinomas of the minor salivary glands.

Background: p27(kip1), a universal cyclin-dependent kinase inhibitor, is a useful marker for predicting clinical aggressiveness with various human tumors. In this study, p27 expression was investigated in pleomorphic adenomas (PAs) and adenoid cystic carcinomas (ACCs) of minor salivary glands to evaluate its utility for differentiation purposes. At the same time, the correlation between p27 and ACC grading was evaluated.