Safety of mapping the motor networks in the spinal cord using penetrating microelectrodes in Yucatan minipigs.

Objective: The goal of this study was to assess the safety of mapping spinal cord locomotor networks using penetrating stimulation microelectrodes in Yucatan minipigs (YMPs) as a clinically translational animal model.

Methods: Eleven YMPs were trained to walk up and down a straight line. Motion capture was performed, and electromyographic (EMG) activity of hindlimb muscles was recorded during overground walking.

Machine-learned Adaptive Switching in Voluntary Lower-limb Exoskeleton Control: Preliminary Results.

Lower-limb exoskeletons utilize fixed control strategies and are not adaptable to user's intention. To this end, the goal of this study was to investigate the potential of using temporal-difference learning and general value functions for predicting the next possible walking mode that will be selected by users wearing exoskeletons in order to reduce the effort and cognitive load while switching between different modes of walking. Experiments were performed with a user wearing the Indego exoskeleton and given the authority to switch between five walking modes that were different in terms of speed and turn direction.

Overground gait kinematics and muscle activation patterns in the Yucatan mini pig.

The objectives of this study were to assess gait biomechanics and the effect of overground walking speed on gait parameters, kinematics, and electromyographic (EMG) activity in the hindlimb muscles of Yucatan minipigs (YMPs).Nine neurologically-intact, adult YMPs were trained to walk overground in a straight line. Whole-body kinematics and EMG activity of hindlimb muscles were recorded and analyzed at six different speed ranges (0.