J. Sericin Induces Apoptosis in a Caspase-dependent Manner in A549 and HeLa Cells.

Background: In spite of much progress in cancer, the global cancer burden is still significant and increasing. Sericin, an adhesive protein of silk cocoons, has been shown to be a potential protein in various biomedical applications, including cancer therapeutics. The present study evaluates the anticancer property of sericin from cocoons of J (SAP) against human lung cancer (A549) and cervical cancer (HeLa) cell lines.