The chronotype, the personal predisposition towards morning or evening activities, significantly influences health conditions, sleep, and eating regulations. Individuals with evening chronotypes are often at a higher risk for weight gain due to misalignment between their natural tendencies of functioning and social schedules, resulting in insufficient sleep, disruptions in eating habits, and decreased physical activity levels. Often, impaired glucose tolerance and changes in melatonin, adiponectin, and leptin secretion, along with alterations in the clock gene functions in subjects with evening preferences, may be predisposed to obesity.
View Article and Find Full Text PDFSecond reading is an important part of breast cancer organized screening program. Image quality control and detection of non-diagnosed cancer by first reader are the two goals of this process. In France, 6 % of all screening cancer are diagnosed by second reading, actually done on screen film.
View Article and Find Full Text PDFA case is presented of anaerobic osteomyelitis with intraosseous pneumatosis resulting in extension of gas in soft tissue structures and femur in a patient with mitral valve vegetation and bacteremia. The finding of intraosseous pneumatosis and its extension into the hip joint, iliopsoas bursa and subgluteus medius bursa is depicted. Intraosseous pneumatosis is a rare but concerning finding for osteomyelitis in the absence of a penetrating wound, recent surgery, biopsy or fracture.
View Article and Find Full Text PDFThe success of treating cancerous tissue with heat depends on the temperature elevation, the amount of tissue elevated to that temperature, and the length of time that the tissue temperature is elevated. In clinical situations the temperature of most of the treated tissue volume is unknown, because only a small number of temperature sensors can be inserted into the tissue. A state space model based on a finite difference approximation of the bioheat transfer equation (BHTE) is developed for identification purposes.
View Article and Find Full Text PDFInt J Hyperthermia
October 1993
Multiple model estimation is a viable technique for dealing with the spatial perfusion model mismatch associated with hyperthermia dosimetry. Using multiple models, spatial discrimination can be obtained without increasing the number of unknown perfusion zones. Two multiple model estimators based on the extended Kalman filter (EKF) are designed and compared with two EKFs based on single models having greater perfusion zone segmentation.
View Article and Find Full Text PDFThis paper analyzes the feasibility of using reduced-order modeling techniques in the design of multiple-input, multiple-output (MIMO) hyperthermia temperature controllers. State space thermal models are created based upon a finite difference expansion of the bioheat transfer equation model of a scanned focused ultrasound system (SFUS). These thermal state space models are reduced using the balanced realization technique, and an order reduction criterion is tabulated.
View Article and Find Full Text PDFBreast reconstruction in female patients undergoing mastectomy for breast cancer (17 patients) or benign breast disease (2 patients), and malformation of breast due to asymmetry (19 patients) was started in 1983. Mastectomy in 10 patients was performed because of the cancer, and in 17 patients due to benign breast disease. Age of patients ranged from 15 to 58 years.
View Article and Find Full Text PDFFluorine-18 acetyl hypofluorite, produced by a gas/solid-phase reaction, was reacted with D-glucal in water, followed by treatment with HCl and serial passage through columns of charcoal, ion-retardation resin, and alumina. The product was an injectable solution of 2-[18F]fluoro-2-deoxy-D-glucose. The radiochemical purity was greater than 95% and the radiochemical yield was about 40%.
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