Evolution in pecunia.

The paper models evolution in pecunia-in the realm of finance. Financial markets are explored as evolving biological systems. Diverse investment strategies compete for the market capital invested in long-lived dividend-paying assets.

[Inflammatory nature of colon diverticula].

On the basis of morphological and immunological study of biopsies of the colon in patients with diverticulosis was revealed that microscopic inflammation of the mouth of the diverticulum is characterized by several features that include excessive proliferation of the epithelium, the predominance of macrophage reaction in the development of the immune response, increased cell adhesion and unusual ratio between the expression of cytokines and other regulatory molecules. Changes in the structure of the formed diverticula tissue are associated with dysregulation of many processes of tissue metabolism and morphogenesis. These include the dysregulation of cell renewal of the epithelium (increased level of proliferation of epithelial cells and inhibition of apoptosis), degradation of extracellular matrix components, moderate vascular reaction.

[Clinical and morphological variants of diverticular disease in colon].

Our own results of two-stage research are presented in the article. The first stage contains the retrospective analysis of 3682 X-ray examining of large bowel which were conducted in 2002-2004 to define the structure of colon disease and to determine gender differences. The second stage is prospective research which took place from 2003 to 2012 and 486 patients with diverticular disease were regularly observed.

Regeneration of colorectal epithelium in diverticulosis.

Excessive poorly differentiated epitheliocytes were detected in the crypts and subepithelial regions of the colorectal mucosa during the regeneration process in the majority of patients with diverticular disease. The compensatory reaction of the sigmoid mucosa decreased, which was seen from rarely detected cryptic hyperplasia. Disorders in the epitheliocyte proliferation and differentiation were paralleled by changes in tissue levels of proinflammatory cytokines (elevation of TNF-α and IFN-γ and reduction of IL-1β and IL-8) and increase of IL-4, regulating lymphocyte activation.

[Child psychoanalysis and child psychiatry in Russia, from Lenin to the present day].

Russian child psychiatry and psychoanalysis painfully recover after being brought under the subjection of "paedology", a synthetic so-called science, and enslaved to the utopian Soviet expectation of building a "new man" in 1920-1930. Later on, in 1940-1980, under the precarious shelter of Soviet social work, they could indulge in the psychodynamic viewpoint. Liberated in 1985-1991, Russian child psychiatry and psychoanalysis take up again with Western science to answer the urgent demand for care for the psychic sufferings of young Russians.

[Structural changes of esophageal mucosa at metabolic syndrome].

In metabolic syndrome including the connection with gastro-esophageal rephlux it was detected some equal dystrophic changes in esophageal mucosa. These changes are: horny epithelium, destruction in epithelial-stromal interactions, a special form of papilla, some spherical structures with dystrophic epithelial cells and groups of epitheliocytes with nuclear absence. These changes occurred against a background of NO increased level.

[Specific immune response in diagnosis of celiac disease with chronic diarrhea].

High concentration of Ab Gl, Ab tTG, Ab Em and Ab Rt and increased amount of immunocompetent cells in the SIM in coeliac disease is an index of the developing specific immune response to gliadin and tissue antigens. High specificity and sensitivity of Ab tTG and Ab Em were determined in celiac disease.

[Response of immunocompetent cells and structural changes of colon mucosa in patients with diverticulum disease].

It was established the activisation of macrophages and plasma cells with raise their adhesion in diverticular disease. The express of immune response depends on unit or plural diverticuls. Epithelial cells proliferation is on the increase in the cript and mouth region of diverticul.

[On the issue of pylorostenosis modeling].

Pylorostenosis was modeled by putting a slightly compressing ligature in the boundary between the antral part of the stomach and the duodenum. Subcompensated pylorostenosis developed on the 10th day; decompensated pylorostenosis developed on the 15th day.

[The role of the serotoninergic system in the pathogenesis of experimental ulcerous colitis].

Ulcerous colitis was modeled in a rat experiment by introducing picrylsulfonic acid. The role of serotoninergic structures in the pathogenesis of ulcerous colitis was studied by preliminary administration of serotonin or spiperone, a 5-HT2 serotonin blocker. Spiperone was shown to inhibit the damaging action of picrylsulfonic acid during the first ten days of the beginning of modeling, and to accelerate reparative processes.

Effect of serotonin on gonadal function.

The role of endogenous serotonin in the regulation of spermato- and oogenesis was studied in experiments on rabbits. The involvement of the peripheral serotoninergic structures in the studied processes is demonstrated.

[Experimental study on the effect of low molecular DNA from salmon milt on hemopoiesis].

Biological activity of low molecular DNA isolated from salmon milt was studied. When administered subcutaneously to mice with with acute experimental radiation disease in a course dose of 10 mg/kg, it showed a therapeutic effect, stimulated hemopoiesis, increased the survival rate and the average life span of the animals. Moreover, its marked effect on the humoral immunity was observed.

[Complicated form of chronic stomach ulcer].

Stomach ulcer is one of the most important problems of gastroenterology. Complicated, often recurring, giant and refractory stomach ulcers are most complex in the pathogenetic and treatment regard. The chronic and often recurring course of the disease, high percent of complications including such severe ones as perforation and bleeding, malignization, penetration and stenosis quite often result in a partial or complete disability in patients.

[Frequency of relapse and gigantic stomach ulcers].

Frequently recurrent stomach ulcers are ulcers that exacerbate 2-3 times per year. Indolent ulcers are ulcers for which there is no healing during three months of continuous treatment.

[The characteristics of peptic ulcer in subjects with concomitant ischemic heart disease].

Aim: The study of clinical running of gastric or duodenal ulcer in associated coronary heart disease (CHD).

Materials And Methods: 209 CHD patients with gastric ulcer (GU) or duodenal ulcer (DU) were examined clinically plus histological examination of gastric or duodenal mucosa biopsies was made.

Results: In CHD patients GU occurred more frequently (56%) than DU.

[Characteristics of the gastric and duodenal mucosa in participants in the cleanup of the sequelae of the accident at the Chernobyl Atomic Electric Power Station].

Morphological electron-microscopic evaluation of gastroduodenal mucosa in subjects who worked in the zone of radionuclide contamination after the Chernobyl accident in 1986-1987 and therefore exposed to low-dose ionizing radiation (18, 62 sGy on the average) discovered deficiency of tissue immunocompetent cells, dystrophic changes in the epithelium and stroma. In epithelial cells there were structural shifts in microvillae, organoids and nuclei. Epithelium, stroma and endothelium of blood vessels contained dark cells with thick hyaloplasm.

[The characteristics of gastroduodenal pathology in the workers of a plant for plastic construction materials].

Out of 162 workers exposed to chemicals in the manufacture of construction plastics an outpatient and inpatient examination revealed gastrointestinal problems in 84.3%, vegetative nervous disorders in 62.6% of the examinees.

[Antipyrine metabolism and rat liver ultrastructure in single and combined action of trichlorodiphenyl and dioctyl phthalate].

As shown by animal experiments, low-dose trichlorodophenyl and dioctyl phthalate induce microsomal cytochrome P-450-dependent enzymes and ultrastructural changes in hepatocytes. This evidences hepatotoxicity of the compounds.

[Effect of laser irradiation of different intensities on the processes of healing of stomach ulcers].

Patients with stubborn peptic ulcers were exposed to copper vapor laser of various intensities with similar irradiation energy. The best therapeutic effect (more rapid ulcer healing) was achieved when ulcer bottom and edges were exposed to laser of higher intensity; the effect is explained by a higher stimulation of inflammation and a more rapid and clear-cut restructuring of connective-tissue stroma on ulcer bottom.

[Ultrastructural characteristics of autorosette formation in vivo].

The interaction of extravascular erythrocytes with lymphocytes, macrophages, polymorphonuclear leucocytes and fibroblast like cells in human gastric ulcer and in post-ulcer scar was studied by means of electron microscopy and cytochemical methods. It was shown that such interaction results in autologous rosette formation. There were also autorosette in the capillaries where autorosette forming cells were endothelial cells and lymphocytes.