[Intensification and effectiveness of scientific research in hygiene (several problems of information supply)].

The nature of the concept "intensification" and the notions effect and effectiveness, associated with it are discussed. The nature of the separate kinds effect, obtained in hygienic science are determined - primary (health) and secondary (derivative). Effectiveness is determined on that base - as juxtaposition of the kinds of effects obtained with the resources spent in the field of hygienic science.

[Clinico-morphological characteristics of status thymicolymphaticus in adolescents and adults].

Analysis of 18 autopsy observations of status thymicolymphaticus (STL) in patients aged from 14 to 44 years is presented. The clinical diagnosis of STL in adults was shown to be unsatisfactory because physicians are not properly acquainted with its clinical manifestations. The latter are in some cases conditioned by predominant involvement of the endocrine system, in others by incompetence of immunogenesis.

[Chronic active hepatitis and generalized viral infection].

Virus infection of organs and tissues in chronic active hepatitis (CAH) is generalized, therefore CAH may be considered to be a generalized viral infection in which liver involvement is only one but most important manifestation thereof. The involvement of both liver and other internal organs in CAH is underlain by delayed type hypersensitivity reaction supported by immune complexes containing hepatitis B virus antigens. The intensity of hypersensitivity reaction (immune inflammation) and autoimmunization is mediated genetically.

[Primary biliary liver cirrhosis with a granulomatous reaction].

An observation of primary biliary hepatocirrhosis with granulomatous reaction in a woman of 50 is presented. The disease for 3 years was accompanied by hepatic cholestasis. Diagnostic laparotomy done to exclude the mechanical nature of cholestasis revealed cholecystolithiasis, and cholecystectomy was performed.

[Dynamics of chronic active hepatitis with varying degrees of severity].

Clinico-morphological examinations (repeated laparoscopies, histological and electron microscopic examinations of liver biopsies) were performed in 30 patients with chronic active hepatitis (CAH), in 20 of them in the time course of the disease. In 25 patients the viral etiology of CAH was established, in 5 patients the etiology remained obscure. In most cases of CAH there was a correlation between the intensity of clinico-laboratory and morphological manifestations of the disease activity.

[Structure of thromboembolic complications (based on prosection data of the Department of Pathological Anatomy of the I. M. Sechenov I Moscow Medical Institute from 1962 to 1979)].

Based on the study of the materials of 13,000 autopsies made in 1962--1979 at the Pathology Department of the Chair of Pathological Anatomy of the I. M. Sechenov First Medical Institute, an increase in the rate of thromboembolic complications (TEC) was established predominantly in diseases of the cardiovascular system (atherosclerosis, hypertension, ischemic heart disease, rheumatic disease, protracted bacterial endocarditis).

[Characteristics of the energy of electrostatic interaction of the formed elements of blood in experimental myocardial ischemia].

The diffusion and z-potentials of red cells of the blood outflowing from the zone of myocardial ischemia through the branch of the large cardiac vein were studied during acute period of experimental myocardial infarction. This enabled one to calculate the energy of electrostatic repulsion (EER) between blood constituents and to identify the factors exerting a significant effect on this value in acute experimental myocardial infarction induced in 20 dogs by ligation of the anterior interventricular branch of the left coronary artery. It was shown that the energetic state of the double electric lesion is the leading factor in the changed EER and in manifestation of the aggregation activity by the blood constituents.

[New materials on the history of veterinary medicine in Bulgaria].

Several tens of ritual plates are preserved in Bulgaria on which elements of glorification are found of god Mithras who gained popularity particularly in the 1st-IIIrd century in the regions of Thrace and today's North Bulgaria, then provinces of the Eastern Roman Empire. Mithras seemed to be respected by slaves, soldiers, and merchants alike, but was also an exemplar to the Roman emperors, being considered by them as Sol invictus or Deo invicto. The central scene in all plates is that of Mithras tauroctonus (Mithras, the killer of bulls).

[Influence of fermentation inhibitors on the rate of glutathione accumulation by yeast during fermentation].

During incubation of the yeast Saccharomyces cerevisiae in the sucrose medium fluorine ions inhibited fermentation and, consequently, reduced the rate of accumulation of SH-compounds, primarily as glutathione, in the medium. Ethanol inhibition of the fermentation resulted in the general degradation of metabolism of the yeast cell and an increase of the content of SH-compounds in the medium.