One of the critical aspects in advancing high-brightness field emitter devices is determining the conditions under which single-tip emitters should be constructed to optimize their emission area. Recent experiments have explored varying the axis ratio ξ of the cap of a single-tip emitter, ranging from an oblate semi-spheroid to a prolate shape, mounted on a nearly cylindrical conducting body. In this work, we present a strategy, based on high-accuracy computer simulations using the finite element technique, to maximize the emission area of those single-tip emitters.
View Article and Find Full Text PDFThe search for dependable molecular biomarkers to enhance routine clinical practice is a compelling challenge across all oncology fields. Urothelial bladder carcinoma, known for its significant heterogeneity, presents difficulties in predicting responses to systemic therapies and outcomes post-radical cystectomy. Recent advancements in molecular cancer biology offer promising avenues to understand the disease's biology and identify emerging predictive biomarkers.
View Article and Find Full Text PDFThis work presents for the first time the possibility of reducing and tuning the work function of field emission cathodes coated with metal oxides by changing the chemical composition of oxide coatings using an example of heat-treated CNT/NiO nanocomposite structures. These cathodes are formulated using carbon nanotube (CNT) arrays that are coated with ultrathin layers of nickel oxide (CNT/NiO) by atomic layer deposition (ALD). It was found that NiO at thicknesses of several nanometers grown on CNTs heat treated at a temperature of 350 °C can change its stoichiometric composition towards the formation of oxygen vacancies, since the Ni/Ni peak area ratio increases and the position of the Ni-O peak binding energies shifts as observed using X-ray photoelectron spectroscopy (XPS).
View Article and Find Full Text PDFTwo new species of ( and ) discovered during an investigation of the mycobiota of Central Vietnam (Kon Chu Rang Nature Reserve; Ta Dung National Park; Bidoup-Nui Ba National Park; Kon Ka Kinh National Park) are described on the basis of molecular and morphological data. Illustrated descriptions of their macro- and microscopic features and discussion on similar taxa are given. Additionally, eight species which were recorded for the first time in Vietnam are listed and illustrated here.
View Article and Find Full Text PDFAfter recent approvals, poly-adenosine diphosphate [ADP]-ribose polymerase inhibitors (PARPis) have emerged as a frontline treatment for metastatic castration-resistant prostate cancer (mCRPC). Unlike their restricted use in breast or ovarian cancers, where approval is limited to those with BRCA1/2 alterations, PARPis in mCRPC are applied across a broader spectrum of genetic aberrations. Key findings from the phase III PROPEL trial suggest that PARPis' accessibility may broaden, even without mandatory testing.
View Article and Find Full Text PDFThe study examined the modes of pulsations of the femoral and carotid arteries of rats in situ (n=14) during acute blood loss, which sequentially caused a deep BP drop, cardiac and respiration arrest, and termination of ECG signals. When BP dropped to 19 (13; 26) mm Hg, the mechanosensitivity of passively pulsing arteries determined by the ratio of the swing range of electroimpedance oscillations of arterial segment to pulse pressure increased by 3.2 (2 ; 4) times (p<0.
View Article and Find Full Text PDFWe experimentally demonstrate critical coupling in miniature grating-coupled resonators known as cavity-resonant integrated-grating filters (CRIGFs). Using previously proposed asymmetric grating coupler designs for non-linear CRIGFs, and introducing a dedicated variant of a coupled-modes theory model to estimate physical properties out of the measured reflection and transmission characteristics of these resonators, we demonstrate fine control over the in-and out-coupling rate to the resonator while keeping constant both the internal losses and the resonant wavelength. Furthermore, the critical coupling condition is also observed to coincide with the maximum enhancement of the second harmonic generation signal.
View Article and Find Full Text PDFUnlabelled: is to find new predictors of postablation atrial fibrillation (AF) recurrence in patients with lone AF using a texture analysis of the periatrial adipose tissue (PAAT) of the left atrium.
Materials And Methods: Forty-three patients admitted for lone AF catheter ablation, who had undergone multispiral coronary angiography, were enrolled in the study. PAAT segmentation was performed using 3D Slicer application followed by extraction of 93 radiomic features.
The urea breath test is a non-invasive diagnostic method for infections, which relies on the change in the proportion of CO in exhaled air. Nondispersive infrared sensors are commonly used for the urea breath test in laboratory equipment, but Raman spectroscopy demonstrated potential for more accurate measurements. The accuracy of the detection via the urea breath test using CO as a biomarker is affected by measurement errors, including equipment error and δC measurement uncertainty.
View Article and Find Full Text PDFThe gut microbiome is one of the main factors affecting human health. It has been proven that probiotics can regulate the metabolism in the host body. A large number of people use probiotics not as medicines, but as a prophylactic supplement.
View Article and Find Full Text PDFEighteen specimens of collected from the tropical forests of Vietnam were studied using morphological and molecular approaches. , , and are registered as additional or new records for Vietnam. Four species (, , , and ) are proposed as new to science, and several other collections ( sp.
View Article and Find Full Text PDFThe aim of the present paper was to evaluate the effect of neutron activation on TiSiCN carbonitrides coatings prepared at different C/N ratios (0.4 for under stoichiometric and 1.6 for over stoichiometric).
View Article and Find Full Text PDFObjective: The purposes of this multi-center study were to evaluate the rate of infection stones and to evaluate the urine cultures of patients with infection stones.
Materials: Charts of adulpatients with urinary stones were reviewed and data on stone analyses and urine cultures were collected.
Results: In total, 1204 renal stone formers (RSFs) from 10 countries were included (776 males, 428 females).
The paper considers the new effects of the nanoscale state of matter, which open up prospects for the development of electronic devices using new physical principles. The contacts of chemically homogeneous nanoparticles of yttrium-stabilized zirconium oxide (ZrO2—x mol% Y2O3, x = 0, 3, 4, 8; YSZ) with different sizes of 7.5 nm and 9 nm; 7.
View Article and Find Full Text PDFWe demonstrate the possibility of applying surface-enhanced Raman spectroscopy (SERS) combined with machine learning technology to detect and differentiate influenza type A and B viruses in a buffer environment. The SERS spectra of the influenza viruses do not possess specific peaks that allow for their straight classification and detection. Machine learning technologies (particularly, the support vector machine method) enabled the differentiation of samples containing influenza A and B viruses using SERS with an accuracy of 93% at a concentration of 200 μg/mL.
View Article and Find Full Text PDFThis paper provides a demonstration-of-concept of a new methodology for comparing field electron emission (FE) theory and experiment. It uses the parameter in the mathematical equation = exp[-/ ] (where and are weakly varying or constants) that is taken to describe how measured current depends on measured voltage for electronically ideal FE systems (i.e.
View Article and Find Full Text PDFWe report on the design of cavity-resonator integrated grating couplers for second-harmonic generation. The key point is that the base pattern of our grating coupler (GC) is made of two ridges with different widths (bi-atom). Thus, we reach extremely high Q-factors (above 10) with structures whose fabrication is not challenging, since the bi-atom base pattern is close to that of the surrounded distributed Bragg reflectors (DBR).
View Article and Find Full Text PDFBackground: Epicardial adipose tissue (EAT) has been considered as one of the probable triggers of atrial fibrillation (AF). CT-rediomics is a perspective noninvasive method of assessment of EAT. We evaluate the radiomic phenotype of EAT in patients with lone AF in the prognosis of AF recurrence after catheter ablation.
View Article and Find Full Text PDFIn this paper, dielectric Cavity-Resonant Integrated-Grating Filters (CRIGFs) are numerically optimized to achieve extremely high-quality factors, by optimizing the cavity in/out-coupling rate and by introducing apodizing mode-matching sections to reduce scattering losses. Q-factors ranging between 0.1 and 50 million are obtained and two different domains are distinguished, as a function of the perturbation parameter which controls the cavity in/out-coupling rate.
View Article and Find Full Text PDFThe paper presents a study of a large-area field emitter based on a composite of vertically aligned carbon nanotubes covered with a continuous and conformal layer of nickel oxide by the atomic layer deposition method. The arrays of carbon nanotubes were grown by direct current plasma-enhanced chemical vapor deposition on a pure Si substrate using a nickel oxide catalyst which was also deposited by atomic layer deposition. The emission characteristics of an array of pure vertically oriented carbon nanotubes with a structure identical in morphology, covered with a layer of thin nickel oxide, are compared using the data from a unique computerized field emission projector.
View Article and Find Full Text PDFCavity resonator grating filters (CRIGFs) integrated on lithium niobate on insulator (LNOI) with electrical tuning elements are reported. The resonance wavelength of the filters is in the 780 nm range. Integrated thermo-optical tuning range of 2.
View Article and Find Full Text PDFObesity is a problem of modern health care that causes the occurrence of many concomitant diseases: arterial hypertension, diabetes mellitus, non-alcoholic fatty liver disease, and cardiovascular diseases. New strategies for the treatment and prevention of obesity are being developed that are based on using probiotics for modulation of the gut microbiota. Our study aimed to evaluate the bacterial composition of the gut of obese patients before and after two weeks of lactic acid bacteria (, , , and ) intake.
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