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Publications by authors named "Poongothai A Ramaswamy"

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Synopsis of recent research by authors named "Poongothai A Ramaswamy"

  • - Poongothai A Ramaswamy's research primarily focuses on understanding the interaction between Mycobacterium tuberculosis proteins and the host immune response, specifically examining the regulatory roles of these proteins in macrophage activation.
  • - In a significant study published in 2009, Ramaswamy investigated the PPE18 protein of Mycobacterium tuberculosis, revealing its capability to stimulate IL-10 production in macrophages, thereby promoting a Th2 immune response.
  • - The study highlighted that PPE18 interacts specifically with TLR2, leading to the activation of p38 MAPK, which is essential for the induction of IL-10, thus providing insights into how tuberculosis may evade the host's immune system.

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