Publications by authors named "Poong Hoon Lee"
Background: Despite the proven effectiveness of oral antivirals against severe acute respiratory syndrome coronavirus 2 in randomized trials, their clinical reevaluation is vital in the context of widespread immunity and milder prevalent variants. This study aimed to assess the effectiveness of oral antivirals for coronavirus disease 2019 (COVID-19).
Methods: This retrospective cohort study utilized a target trial emulation framework to analyze patients with COVID-19 aged 60+ from January to December 2022.
Article Synopsis
- A study was conducted to evaluate the safety of COVID-19 treatments nirmatrelvir/ritonavir (NMVr) and molnupiravir (MOL) by comparing acute complications in treated versus untreated patients.
- Data from nationwide databases were used to analyze results from over 700,000 NMVr users and over 150,000 MOL users, focusing on specific cardiac and neurological events.
- The findings revealed that both NMVr and MOL users had a lower risk of certain serious side effects like atrial fibrillation and dysgeusia, suggesting these treatments may be effective in reducing acute complications linked to COVID-19.
Objective: It remains unknown whether cancer risk differs among the three subtypes of anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) and what the cancer risk factors are. We conducted a nationwide study in Korea to evaluate the risk of cancer in patients with AAV and to identify the risk factors for cancer.
Methods: We analyzed the Health Insurance Review and Assessment database of Korea and identified 1982 patients diagnosed with AAV between January 1, 2007 and December 31, 2017.