Formulation, characterization and in-vivo evaluation of standardized Tabernaemontana divericata extract hydrogel for wound healing.

Background: Tabernaemontana divaricata (TD) from the Apocynaceae family exhibits traditional therapeutic properties such as anti-inflammatory, antioxidant, and acetylcholinesterase activity, etc. OBJECTIVE: To formulate and evaluate the wound healing potential of standardized ethanolic extract of TD leaves hydrogel on experimental models of wounds in Wistar rats with the design of experiment approach.

Methods: The prepared PVA-based hydrogel of TD extract was evaluated.