Synopsis of recent research by authors named "Pooladanda Venkatesh"
- Pooladanda Venkatesh's recent research primarily investigates the mechanisms of cancer metastasis and potential therapeutic targets, especially in lymphangioleiomyomatosis (LAM) and ovarian cancer, highlighting the role of extracellular vesicles and specific glycoproteins, such as Sialyl-Tn, in disease progression.
- His studies also emphasize the importance of understanding reactive oxygen species (ROS) in chemotherapy resistance and sensitivity, showcasing pathways that involve both mitochondrial and nuclear interactions, which could influence treatment outcomes for various malignancies.
- Venkatesh's work extends to novel therapeutic strategies, such as the use of niclosamide in targeting epithelial-mesenchymal transition in melanoma, and exploring the implications of acute respiratory distress syndrome (ARDS) on tumor metastasis, revealing interconnectedness between inflammation and cancer progression.
