Neutralizing antibodies from prior exposure to dengue virus negatively correlate with viremia on re-infection.

Background: India is hyperendemic to dengue and over 50% of adults are seropositive. There is limited information on the association between neutralizing antibody profiles from prior exposure and viral RNA levels during subsequent infection.

Methods: Samples collected from patients with febrile illness was used to assess seropositivity by indirect ELISA.