Publications by authors named "Pooja Gusain"
Prefrontal cortex (PFC) intrahemispheric activity and the interhemispheric connection have a significant impact on neuropsychiatric disorder pathology. This study aimed to generate a functional map of FC intrahemispheric and interhemispheric connections. Functional dissection of mouse PFCs was performed using the voltage-sensitive dye (VSD) imaging method with high speed (1 ms/frame), high resolution (256 × 256 pixels), and a large field of view (∼10 mm).
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- Dendritic spines act as small compartments that can influence synapse efficiency, and the study analyzed changes in these spines based on stimulation.
- Researchers created a genetically modified mouse line (AiCE-Tg) that expresses a fluorescently tagged protein (EGFP-CapZ) to observe its behavior in response to sensory stimulation.
- The study found that after stimulation, EGFP-CapZ accumulation increased in certain spines on the stimulated side, suggesting a novel molecular event linked to synaptic plasticity and memory mechanisms.
Chirality plays a vital role in biological membranes and has a significant effect depending on the type and arrangement of the isomer. Menthol has two typical chiral forms, d- and l-, which exhibit different behaviours. l-Menthol is known for its physiological effect on sensitivity (i.
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