[Benefits of volumetric to facial rejuvenation. Part 2: Dermal fillers].

Injectable substances known as fillers are used to palliate age-related atrophy and ptosis, and for their so-called "pseudo-lifting" action. They do not replace face and neck lift, but allow it to be postponed or, when injected after surgical lifting, make the result durable. Hyaluronic acid has a predominant and unchallenged place among fillers, well ahead of poly-L-lactic acid or calcium hydroxyapatite.

Retinaldehyde/hyaluronic acid fragments: a synergistic association for the management of skin aging.

Background: Retinaldehyde (RAL) was proven effective in treating photodamaged skin. Topical treatments with specific intermediate-size hyaluronate fragments (HAFi, 50-400 kDa) have been shown to stimulate keratinocytes proliferation and epidermal hyperplasia. The aim of this open, multicentric, international study was to assess the efficacy of the combination RAL-HAFi in the correction of skin photoaging.

Fragrance allergy: assessing the safety of washed fabrics.

Background: Previously, a quantitative risk assessment suggested there was no risk of induction of fragrance allergy from minor residues of fragrance chemicals on washed fabrics.

Objective: To investigate whether there was any risk of the elicitation of contact allergy from fragrance chemical residues on fabric in individuals who were already sensitized.

Methods: Thirty-six subjects with a positive patch test to isoeugenol (n = 19) or hydroxyisohexyl 3-cyclohexene carboxaldehyde (n = 17) were recruited.

[Adverse reactions to injectable fillers].

The number of "fillers" grows constantly and allows responding to an ever larger demand with mostly hyaluronic acid or collagen based products. However, products degrading more slowly, containing polylactic acid or bioactive ceramics. All these products bring in general satisfactory results.

[Skin testing with cosmetics brought in by patients].

Detailed analysis of symptoms indicates which skin tests should be performed in a patient presenting an allergic reaction to cosmetics: the tests should be read after 15 to 60 min for immediate reactions and after 48 and either 72 or 96 h for eczematous reactions. If the results are inconclusive, additional tests should be performed (ROAT, re-test, usage test). Discrepancies between clinical symptoms and tests results should raise a suspicion of false-positive or false-negative tests.

[Classification of the fillers available in France].

In the last few years the number of dermal filler products has increased in a spectacular manner, thus offering multiple treatment possibilities acting on skin aging and natural or aging related morphological changes. Hyaluronic acid products, with various concentrations and crosslinking levels, provide very good results on the whole cutaneous and subcutaneous skin alterations. Volumator products, especially highly crosslinked hyaluronic acid and L.

[Adverse reactions to injectable fillers].

The number of "fillers" grows constantly and allows responding to an ever larger demand with mostly hyaluronic acid or collagen based products. However, products degrading more slowly, containing polylactic acid or bioactive ceramics. All these products bring in general satisfactory results.

Dry skin in dermatology: a complex physiopathology.

Dry skin (xerosis) is a common dermatosis affecting people of varying skin types and ages and various areas of the body. It is associated with both skin thickening and skin thinning and is triggered by both exogenous (e.g.

Emedastine difumarate versus loratadine in chronic idiopathic urticaria: a randomized, double-blind, controlled European multicentre clinical trial.

Emedastine difumarate (2 mg b.i.d.

Sensitive skin: a complex and multifactorial syndrome.

Many people complain of discomfort after application of commonly used skin care products, particularly to the face. This hyperreactivity of the skin is a non-immunologically mediated skin inflammation. It seems to be the result of an intolerance of the skin to various stimuli that are normally well tolerated.

Fragrance allergy: assessing the risk from washed fabrics.

The prevalence of contact allergy to fragrance ingredients increased during the last part of the 20th century with the consequence that a substantial number of individuals are at risk of experiencing allergic contact dermatitis (ACD) if they have a sufficient degree of skin exposure to the chemical to which they have become sensitized. Such exposure does not necessarily have to arise from the type of source that originally induced the sensitization. A number of sources of exposure are clearly associated with risk of elicitation of ACD, but the role of fragrance deposited on fabrics, for example as a result of laundry processes, also can be questioned.

[Allergies to cosmetics].

The protean clinical delayed hypersensitivity reactions or the less common immediate hypersensitivity reactions can raise major diagnostic challenges, particularly as sensitisation can occur directly, indirectly or from a distance, with the allergen being handborne, airborne, or transmitted vicariously. Identification of the offending allergen among the vast array of potential candidates requires an exhaustive evaluation. The most common offenders are fragrances, which are ubiquitous, being found in a host of known or occult sources preservatives, hair dyes, excipient component, formaldehyde resins, and acrylic resins.

[Contact allergy to antiseptics: 75 cases analyzed by the dermato-allergovigilance network (Revidal)].

Aim: To determine the clinical features of contact dermatitis caused by antiseptics and to ascertain whether the substance responsible is the antiseptic itself or the excipients.

Patients And Methods: A multicenter, retrospective study based on analysis of all cases reported over a 2-year period to the Dermato-Allergology Vigilance network known as Revidal. Each dossier contained details of the clinical characteristics of lesions, the incriminated antiseptic, the mode of exposure and the results of patch tests done with the antiseptic in question.

[Slowly absorbable and non absorbable injectable products].

Products which are non absorbable or slowly absorbable make the correction of facial wasting of any origin possible. These highly efficient products are unfortunately sometimes responsible for complications or even undesirable after effects. In order to avoid this the following are necessary: clinical and histological analysis of facias granulomas, a proposal for guidelines for their use which would predict in situ tolerance.

Allergic contact dermatitis from shellac in mascara.

We report 6 cases of allergic contact dermatitis of the eyelids due to mascara. Allergy occurred in women aged 17-34 years, between September 1999 and June 2001. The main ingredient responsible for allergy was shellac, which gave positive patch test reactions in 5/5 patients.

Tolerance profile of a sterile moisturizer and moisturizing cleanser in irritated and sensitive skin.

Background: This study evaluates the tolerance of preservative free sterile cleanser and sterile moisturizer in irritated and sensitive face skin.

Materials And Methods: An exploratory, open-label study using the cleanser and the moisturizer in combination was performed with 98 patients with a documented history of allergic contact dermatitis. The 2 products could each be used once or twice daily for 28 days.