Comparative evaluation of the effect of ultrasonic and rotary agitation of herbal irrigating solutions on smear layer: A SEM study.

Context: Instrumentation and irrigation balance helps in effective removal of endodontic microbes housing inside the smear layer.

Aim: This study aimed to (1) evaluate whether activation of the irrigating solutions with two different systems during the final irrigation step can lead to smear layer formation in the middle and apical third of the root canal and (2) evaluate and compare the smear layer removal ability of the aqueous extracts of Emblica officinalis and Morinda citrifolia.

Materials And Methods: A total of 72 single-rooted teeth were prepared up to F4 ProTaper.

Coffee pulp: From a by-product of coffee production to a potential anticariogenic mouth rinse! An study.

Background And Objectives: Dental caries is a prevalent disease despite various efforts made toward its prevention. The drawbacks of the available preventive agents have led to the quest for a potentially more effective agent with fewer adverse effects. Coffee, a local produce of Coorg, is one such herbal alternative.

An evaluation of effectiveness of Xylene, Thyme oil and Orange oil in dissolving three different endodontic sealers.

Aims: The aim of the study is to compare the dissolution effectiveness of xylene, thyme oil, and orange oil on three different endodontic sealers.

Materials And Methods: Standardized stainless steel molds were used to prepare 210 samples (70 for each endodontic sealer). The samples were divided into three groups based on sealers.

Evaluation of effect of low level laser therapy with intracanal medicament on periapical healing: A randomised control trial.

Objective(s): Photobiomodulation, also commonly referred to as low level laser therapy (LLLT), uses light energy to elicit biological responses from the cell and normalise cell function. Using LLLT on bone has been demonstrated to be effective in modulating inflammation, accelerating bone cell proliferation and enhancing the healing process. The objectives of this study were to evaluate postoperative pain and periapical healing in two different groups.

Evaluation of Root Dentinal Damage Associated with ProTaper Gold, WaveOne Gold, and ProTaper Next during Cleaning and Shaping Procedures: An Analysis.

Aim: The purpose of this study is to evaluate and compare the incidence of dentinal defects after root canal shaping using rotary nickel-titanium (Ni-Ti) instruments (ProTaper Gold [PTG] and ProTaper Next [PTN]) and reciprocating instrument (WaveOne Gold [WOG]).

Materials And Methods: One hundred human mandibular premolars with single root and single canal with canal curvature <10° were randomly divided into five groups ( = 20 teeth per group). The root canals were instrumented using hand K-files (positive control), full sequence rotary files PTG and PTN, and reciprocating single-file system WOG.

Comparative evaluation of remineralizing potential of commercially available agents MI paste, Remin pro, and Clinpro using Scanning Electron Microscope and Energy Dispersive X-ray: An study.

Background: According to recent approaches, the prevention of initial dental caries is achieved using certain noninvasive methods. One such method is the topical application of remineralizing agents. Various remineralizing products are commercially available, but their efficacy is uncertain.

Comparison of the Root End Sealing Ability of Four Different Retrograde Filling Materials in Teeth with Root Apices Resected at Different Angles - An Invitro Study.

Introduction: Insufficient apical seal is the significant reason for surgical endodontic disappointment. The root-end filling material utilized should avoid egress of potential contaminants into periapical tissue.

Aim: The aim of this study was to compare the sealing ability of four root-end filling materials MTA, Portland cement, IRM, RMGIC in teeth with root apices resected at 0 and 45 angle using dye penetration method under fluorescent microscope.

Effect of 10% Sodium Ascorbate on Shear Bond Strength of Bleached Teeth - An in-vitro Study.

Background: Patient often requires some additional interventions such as replacement of old restorations, laminates and veneers after bleaching, for aesthetic purposes. The residual oxygen inhibits polymerization of resin based materials which results in reduced bond strength of the restorations. Some techniques are available to solve the clinical problems related to the post bleach compromised bond strength.

Sealing ability of three root-end filling materials prepared using an erbium: Yttrium aluminium garnet laser and endosonic tip evaluated by confocal laser scanning microscopy.

Aims: (1) To compare the sealing ability of mineral trioxide aggregate (MTA), Biodentine, and Chitra-calcium phosphate cement (CPC) when used as root-end filling, evaluated under confocal laser scanning microscope using Rhodamine B dye. (2) To evaluate effect of ultrasonic retroprep tip and an erbium:yttrium aluminium garnet (Er:YAG) laser on the integrity of three different root-end filling materials.

Materials And Methods: The root canals of 80 extracted teeth were instrumented and obturated with gutta-percha.

An In-Vitro Comparison of Micro Leakage Between Two Posterior Composites Restored with Different Layering Techniques Using Two Different LED Modes.

Aim: Composite resins have undergone various advances since their introduction, but their polymerization shrinkage remains a problem. Shrinkage can cause debonding of the restoration and can contribute to postoperative sensitivity, secondary caries, marginal staining and eventual failure of the restoration. So, our aim is to compare the effect of two different placement techniques and two different curing modes in reducing the marginal microleakage of two different composites in Class II cavities, where oblique and horizontal placement techniques and ramp & pulse curing modes of LED are used during the restoration.

Management of palato radicular groove in a maxillary lateral incisor.

This study is to report the rare localization of a radicular groove on the palatal aspect of the maxillary lateral incisor and to discuss the pathology and management of the concomitant endo-periodontal defect. Unilateral palato-radicular groove was located on the Maxillary right lateral incisor of an 18-year-old female patient. The groove was associated with deep local periodontal pocket resulting in pulp necrosis and the formation of a large periapical lesion.

Sealing ability of mineral trioxide aggregate, calcium phosphate and polymethylmethacrylate bone cements on root ends prepared using an Erbium: Yttriumaluminium garnet laser and ultrasonics evaluated by confocal laser scanning microscopy.

Background: Surgical endodontic therapy comprises of exposure of the involved root apex, resection of the apical end of the root, preparation of a class I cavity, and insertion of a root end filling material. Mineral trioxide aggregate (MTA) is now the gold standard among all root end filling materials. MTA is however difficult to handle, expensive and has a very slow setting reaction.

INN-toxin, a highly lethal peptide from the venom of Indian cobra (Naja naja) venom-Isolation, characterization and pharmacological actions.

A novel toxic polypeptide, INN-toxin, is purified from the venom of Naja naja using combination of gel-permeation and ion-exchange chromatography. It has a molecular mass of 6951.6Da as determined by MALDI-TOF/MS and the N-terminal sequence of LKXNKLVPLF.

The cost of pediatric stroke care and rehabilitation.

Background And Purpose: There is little data regarding the cost of pediatric stroke care or the elements that contribute to these costs. We examined costs for poststroke care during the first year after diagnosis and compared these costs with the volume of the cerebral infarct and the level of neurological and functional outcome.

Methods: We identified 39 children who sustained nontraumatic ischemic or hemorrhagic strokes and confirmed the diagnoses by review of medical and radiology records.

Chemistry and structural evaluation of different phospholipase A2 inhibitors in arachidonic acid pathway mediated inflammation and snake venom toxicity.

PLA2 inhibitors specific to Group I and II PLA2 isoforms are therapeutically important as anti-inflammatory molecules and against venom toxicity. From various natural sources diversified molecules with PLA2 inhibition and concomitant neutralization of inflammatory reactions and venom toxicity were characterized. Using these molecules, lead compounds are generated in several laboratories.

Synthesis and efficacy of 1-[bis(4-fluorophenyl)-methyl]piperazine derivatives for acetylcholinesterase inhibition, as a stimulant of central cholinergic neurotransmission in Alzheimer's disease.

The cholinergic hypothesis of Alzheimer's disease (AD) has spurred the development of numerous structural classes of compounds with different pharmacological profile aimed at increasing central cholinergic neurotransmission. Thus proving a symptomatic treatment for this disease are cholinomimetics with the pharmacological profile of acetyl cholinesterase (AchE) inhibitors. The novel bioactive 1-[bis(4-fluorophenyl)-methyl]piperazine derivatives were synthesized under mild conditions using different aryl/alkyl halides and heterocyclic alkyl halides with 1-[bis(4-fluorophenyl)-methyl]piperazine in the presence of powdered potassium carbonate in N,N-dimethylformamide.

Cadmium exposure affects mitochondrial bioenergetics and gene expression of key mitochondrial proteins in the eastern oyster Crassostrea virginica Gmelin (Bivalvia: Ostreidae).

Cadmium is a ubiquitous and extremely toxic metal, which strongly affects mitochondrial function of aquatic organisms in vitro; however, nothing is known about the in vivo effects of sublethal concentrations of this metal on mitochondrial bioenergetics. We have studied the effects of exposure to 0 (control) or 25 microg L-1 (Cd-exposed) Cd2+ on mitochondrial function and gene expression of key mitochondrial proteins in the eastern oyster Crassostrea virginica. Cadmium exposure in vivo resulted in considerable accumulation of cadmium in oyster mitochondria and in a significant decrease of ADP-stimulated respiration (state 3) by 30% indicating impaired capacity for ATP production.