Publications by authors named "Ponman Solomon"
Article Synopsis
- * Research in Nigeria from 2002-2015 identified 73 complete and 38 partial NDV genomes, revealing seven different genotypes and highlighting the genetic diversity of NDV within a single country.
- * The findings indicate frequent transmission of NDV between domestic and wild birds, including previously unreported species, underscoring the need for enhanced monitoring and surveillance to manage NDV’s impact on both agriculture and conservation.
Mycoplasma gallisepticum (MG) is the primary cause of chronic respiratory disease in poultry. We investigated the protective efficacy of the live-attenuated ts-11 and 6/85 MG vaccines against a local MG strain and, in order to enhance signs and mimic a typical field situation, we co-infected birds with a virulent strain of QX-like infectious bronchitis virus (IBV). Both vaccines showed similar ability to protect infected chickens from clinical signs, although ts-11 performed slightly better.
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- Genetic analysis of fourteen Nigerian avian influenza isolates revealed a cleavage site characteristic of highly pathogenic avian influenza (HPAI), with specific amino acid substitutions noted in one isolate.
- Phylogenetic analysis identified two main clusters of HPAI H5N1, with Cluster I closely related to viruses from neighboring West African countries and Cluster II closely associated with viruses from Europe and other West African nations.
- The findings highlight the ongoing HPAI outbreaks in Nigerian poultry and emphasize the need for continual monitoring and characterization of HPAI isolates due to their zoonotic risk.
The first complete genome sequence of a strain of Newcastle disease virus (NDV) of genotype XVII is described here. A velogenic strain (duck/Nigeria/903/KUDU-113/1992) was isolated from an apparently healthy free-roaming domestic duck sampled in Kuru, Nigeria, in 1992. Phylogenetic analysis of the fusion protein gene and complete genome classified the isolate as a member of NDV class II, genotype XVII.
View Article and Find Full Text PDFThe first complete genome sequence of a strain of Newcastle disease virus (NDV) from genotype XIV is reported here. Strain duck/Nigeria/NG-695/KG.LOM.
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- - Four Newcastle disease virus isolates were found in healthy guinea fowl and Muscovy ducks, highlighting their potential role in spreading the virus among poultry.
- - All isolates contained a virulence-related cleavage motif, indicating they are classified as virulent strains from sub-lineage 5 g, previously seen in chickens in Nigeria.
- - This study marks the first report of virulent sub-lineage 5 g Newcastle disease virus in asymptomatic birds in Nigeria, and the high genetic similarity among viruses suggests connections with neighboring countries, indicating possible cross-border disease transmission through live poultry trade.
Newcastle disease (ND), caused by Avian Paramyxovirus Type 1, is a highly contagious and devastating viral disease of poultry of worldwide distribution with an enormous economic impact. Although ND is reported to be endemic in Nigeria, little information exists on the molecular epidemiology and the lineage distribution of the Newcastle disease viruses (NDVs) in the country, especially in the live bird markets (LBMs). Recent studies reported the identification of three unique sub-lineages.
View Article and Find Full Text PDFHighly pathogenic avian influenza (AI) is an infectious disease of agroeconomic and public health importance. The outbreak that occurred in Nigeria (2006-2008) was devastating to the poultry industry and raised public health concerns. In the course of its control, rapid laboratory confirmation of suspected cases in poultry was essential for prompt mobilization of control logistics for depopulation and decontamination of affected premises.
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