Publications by authors named "Ponikowska I"

Background: The present study aimed to calculate the basal metabolic rate (BMR) with the Mifflin equation based on the expected body mass for normal body mass index (BMI) values in obese patients treated in spa conditions.

Methods: Patients with morbid obesity (BMI > 40 kg m ) and non-obese controls (BMI < 30 kg m ) were recruited. In total, 104 patients with morbid obesity (mean BMI ± standard deviation, 46.

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Humic waters (HW) are globally unique, deep underground, dark-brown waters containing humic acids, and they present numerous therapeutic activities including anti-inflammatory. In the present study, we use HW from source in Poland. Diabetes has become an epidemic and is a risk factor of cardiovascular diseases.

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Unlabelled: Poland is high on a list of countries affected by epidemics of obesity, a problem that has especially suddenly increased in the post-transformation period.

Materials And Method: Documentation of 115 subsequent patients diagnosed with grade 3 obesity, considered eligible for surgical treatment, was analysed since 2015. A subgroup of 68 patients was selected from this group and the included patients who decided to cancel their treatment at various stages.

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Article Synopsis
  • The study found that morbidly obese patients are at a high risk for cardiovascular issues due to an overactive coagulation system, as indicated by higher levels of various coagulation markers compared to healthy controls.
  • Despite a 3-week low-calorie diet and treatment, there were no significant changes in these coagulation parameters, suggesting little immediate effect from short-term dietary intervention.
  • The results highlight the need for more extensive weight loss to potentially improve coagulation abnormalities in morbid obesity.
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Objective: The aim of this study was to evaluate the concentrations of C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6), and the degree of homeostasis model assessment-insulin resistance (HOMA-IR) in patients with morbid obesity exposed to a three-week low-calorie diet and balneotherapy.

Methods: The study included 33 patients (25 females and 8 males; mean age 46 years) with body mass index (BMI) values of >40 kg/m(2). Evaluations of CRP, IL-6, TNF-α, lipid profile, HOMA-IR, and fasting glucose were carried out before (baseline data) and three weeks after the treatment.

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Aim: The aim of this study was to evaluate the usefulness of follicle-stimulating hormone (FSH) determination in the postmenopausal women with metabolic syndrome (MetS) in a comparative analysis with biomarkers such as C-reactive protein (CRP), adiponectin, leptin and leptin-to-adiponectin ratio (L/A).

Material & Methods: 135 postmenopausal women with MetS and 153 without MetS were subjected to examinations.

Results: The increase in the probability of MetS, when the value of the marker concentration decreased or increased by 1 standard deviation, was two times higher for FSH-based models than for models including CRP and leptin, and was similar to models including adiponectin and L/A.

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Obesity is a major risk factor for arterial hypertension, coronary artery disease, dyslipidemias, and type 2 diabetes. Spa therapy has long been used for treating obesity and its comorbidities. Enlargement of adipose tissue has been linked to a dysregulation of adipokine secretion and adipose tissue inflammation.

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We aimed at the evaluation of the relationship between adipocyte fatty acid binding protein (A-FABP) and cardiometabolic risk factors in premenopausal and postmenopausal women. Additionally, we compared A-FABP with adipokines related to metabolic syndrome (MetS) such as leptin and adiponectin. 94 premenopausal and 90 early postmenopausal middle-aged Caucasian women were subject to examinations.

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The article encloses definition of water role and its body requirement, review of water balance and management in older persons regarding characteristic of this age group and concomitant disorders. Based on current literature and expert's opinion the recommendations for water consumption were expressed with estimation of insufficient apply and oversupply, evaluation of hydration state, domestic water sources in diet with accent on influence of proper hydration on comfort and good health.

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Introduction: Nonalcoholic fatty liver disease (NFLD) is a heavy healthy problem in well civilized Countries, where obese appear more frequently. Mostly disease has a benign process, but in some radical case might lead to cirrhosis or even to cancer. There is a demand on specific researches about NFLD, cause knowledge about pathogenesis and epidemiology is not clear.

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There is strong evidence for the presence of a functional renin-angiotensin system in human adipose tissue. The aim of our study was to investigate the association of polymorphic variants of angiotensin-converting enzyme gene (ACE I/D) and angiotensin II type I receptor gene (AGTR1 A1166C) with extreme obesity and obesity-associated type 2 diabetes mellitus (T2DM) and to examine their combined effect on extremely obese patients. Overall, no significant associations were detected between ACE and AGTR1 gene polymorphisms and extreme obesity.

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Objectives: We compared the association of follicle-stimulating hormone (FSH) and sex hormone binding globulin (SHBG) with metabolic syndrome (MetS).

Design And Methods: We examined 320 postmenopausal women (148 with MetS and 172 without MetS).

Results: FSH was more strongly associated with MetS probability in the logistic regression model compared to SHBG.

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Objectives: We compared the diagnostic accuracy of CRP and adipocyte fatty acid-binding protein (A-FABP) for the metabolic syndrome (MS).

Design And Methods: We examined 310 middle-aged Caucasian women.

Results: CRP and AFABP values were significantly associated with the MS probability in the logistic regression model.

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Purpose: The aim of this study was to determine the impact of the weight change during 30-40 year follow-up on the prevalence of metabolic syndrome (MS) components, C-reactive protein (CRP) and adiponectin.

Material And Methods: The study included 153 women. Blood pressure, anthropometric and laboratory measures were done at the age of 50-60 years.

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Background: The paper compares the effects of ozone therapy and conventional balneological methods on health condition of patients with obliterative atheromatosis and on serum activity of three lysosomal enzymes.

Material/methods: Sixty-four patients with lower limb ischaemia in the course of obliterative atheromatosis (without diabetes) were enrolled in the study. Thirty-two patients were treated with ozone administered by intravenous infusions and 30-minute aerosol oxygen-ozone baths.

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Unlabelled: The aim of the study was to evaluate plasminogen activators in compare fibrinolysis parameters in patients with atherosclerosis obliterans (AO) and diabetic macroangiopathy (DM) of lover extremities. The study group consist of 40 patients with AO (mean age 59 years) and 40 with DM (mean age 61 years). All the patients were diagnosed as the II stage in Fontaine scale.

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The aim of study was to evaluate the influence of the treatment with oxygen-ozone mixture on the blood plasma antigen concentration of tissue plasminogen activator (t-PA) and von Willebrand factor (vWF) in patients suffering from atherosclerotic disease of lower extremities. The study was performed in the group of 28 (M/F 22/6) patients means aged 64.1 years with atherosclerotic diseases of lower extremities, in whom 2 weeks therapy with oxygen-ozone mixture was used.

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In the present study we measured the amount of 8-oxo-2'-deoxyguanosine (8-oxo-dG) in DNA isolated from lymphocytes of arteriosclerotic patients undergoing ozonetherapy. Treatment of the patients with therapeutic concentration of ozone caused a significant increase over the control value in the amount of 8-oxo-dG of DNA isolated from their lymphocytes. However, only three out of six patients examined responded positively to the treatment in terms of the base damage.

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For assessment of the way of nutrition of obese patients with diabetes mellitus type 2 (insulin-dependent), questionnaire method was used including dietary history data. The study was carried out in 50 patients during weight-losing treatment in our institute. It was found that the mean energy value of daily food ration of the patients was relatively high, exceeding both the value of predicted energy expenditure and the standard values.

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In 30 patients with diabetes type II and macroangiopathy of lower extremities, physical training was applied. This treatment was carried on in our Clinic for average 4 weeks. The following methods were applied: individual exercises of legs once or twice daily for 30-minutes, training in brine swimming pool for 30 minutes every-day, treatment walks with proportioning effort.

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Physical, clinical, biochemical, and functional examinations have been carried out in 70% of patients with diabetes mellitus type 2 treated in health resorts. Patients were treated with diet, drugs, and physiotherapy during a 3-5-week period. It was found, that the whole period of the treatment may be divided into 3 subperiods: period I is characterized by the subjective symptoms produced by the process of adaptation to different environment.

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The aim of these investigations were the estimation of methods and results of treatment obese diabetics over 65 years and presentation of the most common mistakes of treatment. Two groups of elderly obese diabetics type 2 were compared. The first group involved the patients who kept closely to a low caloric diet and they achieved a decrease of their body mass.

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Ten obese patients with normal glucose tolerance, 11 obese with type II diabetes and 15 normal non-obese controls were studied. The submaximal exercise test was made before fasting in all the mentioned 3 groups of patients and in the obese patients after a 10 days fast. The exercise on normal diet did not cause any changes in serum insulin in all groups.

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An analysis of the nutrition was carried out in 50 obese subjects with questionnaire technique. It was found that moderately obese patients received an excess of calories in comparison with the standards and requirements but approximately 25% of the obese subjects of this group was adequately fed. One of the important nutritive errors in the examined obese subjects was significant percentage of fat in the daily ration and relatively low content of the complex carbohydrates.

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The study aimed at developing optimal technique of the physical treatment of headache in the course of cervical migraine. The study involved 65 patients with headache accompanying degenerative lesions to the cervical spine. The patients were divided into two groups.

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