High Burden of Extended-Spectrum β-Lactamase-Producing and Bacteremia in Older Adults: A Seven-Year Study in Two Rural Thai Provinces.

Bloodstream infection surveillance conducted from 2008 to 2014 in all 20 hospitals in Sa Kaeo and Nakhon Phanom provinces, Thailand, allowed us to look at disease burden, antibiotic susceptibilities, and recurrent infections caused by extended-spectrum β-lactamase (ESBL)-producing and . Of 97,832 blood specimens, 3,338 were positive for and 1,086 for . The proportion of isolates producing ESBL significantly increased from 19% to 22% in 2008-2010 to approximately 30% from 2011 to 2014 (-value for trend = 0.