Publications by authors named "Pongjarat Nunanan"

Background: Physical frailty is related with morbidity and mortality in patients with cirrhosis. Currently, there is no approved treatment of frailty in these patients. Here, we evaluated the efficacy of 16 weeks branched-chain amino acids (BCAA) supplementation on frailty in frail compensated cirrhotic patients.

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  • The study investigates the factors that can predict whether gastric intestinal metaplasia (IM) - a condition that can lead to gastric cancer - will improve or worsen, focusing on patients at Thammasat University Hospital in Thailand.
  • The researchers analyzed data from 2,025 patients, finding that factors like age over 65, ongoing H. pylori infection, and diabetes are linked to a higher risk of IM persistence or progression.
  • Results indicated that patients without H. pylori had better chances of regression of IM, while those with the infection were more likely to progress to dysplasia, and a small percentage were later diagnosed with gastric cancer during follow-up.
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  • Hepatocellular carcinoma (HCC) leads to over 200,000 deaths among women annually, particularly impacting those in the ASEAN region; this study focused on female patients at Thammasat University Hospital in Thailand, examining their clinical features and prognostic factors.
  • A total of 187 female HCC patients were analyzed, revealing that older women tend to present with more advanced disease stages and have lower survival rates compared to younger patients, highlighting factors like abdominal pain and advanced HCC stage as indicators of poor prognosis.
  • The research also reviewed data from six other studies involving 543 female HCC patients in the ASEAN, confirming that chronic hepatitis B is a leading cause of HCC and emphasizing the need for early detection to improve survival outcomes
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Background And Aim: Coronavirus disease 19 (COVID-19) has caused over 200 000 deaths worldwide. Thailand announced the first confirmed case outside mainland China in January 2020. The disease also spread widely across Association of Southeast Asian Nations (ASEAN).

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Background: Chronic hepatitis B virus (HBV) infection related hepatocellular carcinoma (HCC) is a major health problem in the Asia-Pacific region including Thailand. Several factors have been proposed as contributing to hepatocarcinogenesis. This study was aimed to investigate the impact of CYP2C19 genotypic polymorphism in HCC related to chronic HBV infection in Thailand.

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Background: Esophageal cancer is one of the major health concerns in Southeast Asian countries, including Thailand. However, only a limited number of studies have been reported from this region. This study was designed to evaluate the prevalence, clinical characteristics and survival rate of esophageal cancer in Thailand.

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