Hypofractionation with concomitant boost using intensity-modulated radiation therapy in early-stage breast cancer in Mexico.

Aim: To evaluate whether hypofractionation with integrated boost to the tumour bed using intensity-modulated radiation therapy is an acceptable option and to determine whether this treatment compromises local control, toxicity and cosmesis.

Background: Retrospective studies have demonstrated that patients who are treated with HF and integrated boost experience adequate local control, a dosimetric benefit, decreased toxicity and acceptable cosmesis compared with conventional fractionation.

Materials And Methods: A retrospective, observational and longitudinal study was conducted from January 2008 to June 2015 and included 34 patients with breast cancer (stage 0-II) who were undergoing conservative surgery.

[Stereotactic radiosurgery with linear accelerator (LINAC). Report of the technical experience in 100 cases treated at the Mexico General Hospital].

Unlabelled: Stereotactic radiosurgery consists of the release and high dose radiation inside the intracraneal, small, well defined and stereotactic localized injury.

Objective: In this study we describe the technical aspects, clinical results and dose radiation levels used in 100 patients treated with LINAC.

Methods: One hundred patients received treatment with LINAC stereotactic radiosurgery, 34 AVM, 22 meningiomas, 18 astrocytomas, 11 pituitary adenomas, 5 cavernous malformations, 3 acoustic neuromas, 3 craniopharyngiomas, 2 cases of epilepsy, one brain metastasis and one ependymoma.