Publications by authors named "Polly Kirsch"
Background And Aims: Pouchitis is an inflammatory condition affecting the ileal pouch in patients' status after ileal pouch anal anastomosis (IPAA). This affects a significant portion of IPAA patients. Our aim was to study the prevalence of active pouch symptoms among currently treated outpatients with endoscopic pouchitis and understand patients' perspective of disease control and quality of life.
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- Cushing's syndrome (CS) has significant neurocognitive and psychiatric impacts that reduce quality of life, prompting a systematic review of affected patients compared to healthy controls and those with non-functioning pituitary adenomas (NFPA).
- The study analyzed 40 eligible research papers, identifying 2603 participants, 45.2% of whom had Cushing's disease (CD), with a focus on their psychiatric symptoms and cognitive performance before and after surgical treatment.
- Findings indicate that higher baseline cortisol levels in patients with CS correlate with worse cognitive function, even post-surgery, and prolonged periods of uncontrolled CS may lead to persistent cognitive challenges.
Metabolic effects of prolactin and the role of dopamine agonists: A review.
Front Endocrinol (Lausanne)
October 2022
Article Synopsis
- Prolactin is a hormone known for its importance in reproduction but is also linked to appetite control and metabolism.
- High prolactin levels are often associated with worse metabolic health, while surprisingly, low levels may also have negative metabolic effects.
- The review covers how prolactin impacts various organs like adipose tissue, pancreas, liver, and small bowel, and discusses how dopamine agonists affect metabolism in patients with high prolactin levels.
Rationale And Objectives: Asymptomatic COVID-19 carriers and insufficient testing make containment of the virus difficult. The purpose of this study was to determine if unexpected lung base findings on abdominopelvic CTs concerning for COVID-19 infection could serve as a surrogate for the diagnosis of COVID-19 in the community.
Materials And Methods: A database search of abdominopelvic CT reports from March 1,2020 to May 2,2020 was performed for keywords suggesting COVID-19 infection by lung base findings.