Temporal resolution of birth rate analysis in zooplankton and its implications for identifying strong interactions in ecology.

Expanding on Haeckel's classical definition, ecology can be defined as the study of strong and weak interactions between the organism and the environment, hence the need for identifying strong interactions as major drivers of population and community dynamics. The solution to this problem is facilitated by the fact that the frequency distribution of interaction strengths is highly skewed, resulting in few or, according to Liebig's law of the minimum, just one strong interaction. However, a single strong interaction often remains elusive.

In Situ Ring-Opening Polymerization of -lactide on the Surface of Pristine and Aminated Silica: Synthesis and Metal Ions Extraction.

The development of functional materials from food waste sources and minerals is currently of high importance. In the present work, polylactic acid (PLA)/silica composites were prepared by ring-opening polymerizations of -lactide onto the surface of pristine (Silochrom) and amine-functionalized (Silochrom-NH) silica. The characteristics of the ring-opening polymerization onto the surface of modified and unmodified silica were identified and discussed.

Method for Determining Treated Metal Surface Quality Using Computer Vision Technology.

Computer vision and image processing techniques have been extensively used in various fields and a wide range of applications, as well as recently in surface treatment to determine the quality of metal processing. Accordingly, digital image evaluation and processing are carried out to perform image segmentation, identification, and classification to ensure the quality of metal surfaces. In this work, a novel method is developed to effectively determine the quality of metal surface processing using computer vision techniques in real time, according to the average size of irregularities and caverns of captured metal surface images.

Uniting Discoveries of Abundance-Size Distributions from Soils and Seas.

Science is a search for patterns but there are few cross-habitat patterns in ecology. We propose key questions following the findings of consistent scaling of abundance versus body mass from bacteria to earthworms and whales, based on an almost forgotten study of soils and a well-known one from the open ocean.

Analysis of the survival of patients with breast cancer depending on age, molecular subtype of tumor and metabolic syndrome.

Aim: To analyze the survival of patients with breast cancer (BC) depending on age, molecular subtype of the tumor and the presence of metabolic syndrome.

Patients And Methods: We have analyzed the results of examination and treatment of 202 patients with BC of stages I-III. The patients were distributed by age into 2 groups.

Molecular-genetic models for prognosis of development of tumors of reproductive system in women with family history of cancer.

Aim: To develop a prognostic molecular genetic model for assessing the risk of development of benign and malignant tumors of female reproductive organs (FRO) in patients from cancer-affected families.

Patients And Methods: The work presents the data on a comprehensive clinical examination of 210 women (90 patients with FRO cancer with aggregation of tumor pathology in families, 65 patients with benign pathology of FRO from cancer-affected families, 55 women - control group of healthy women without family history of cancer). Clinical genealogical analysis, morphological examination of tumors and molecular genetic studies of genomic DNA from peripheral blood and tumors were carried out.

[Isolated pancreatic metastases of renal cell carcinoma].

Aim: To present own experience of surgical treatment of isolated pancreatic metastases of renal cell carcinoma.

Material And Methods: There are 3 cases of pancreatic metastases of renal cell carcinoma. They were diagnosed in women aged 55, 66 and 67 years in 9, 11 and 23 years after nephrectomy respectively.

Association of CD44CD24 with markers of aggressiveness and plasticity of cell lines and tumors of patients with breast cancer.

Aim: To search for additional molecular-biological markers of cancer stem cell (CSC) involved in the development of intra-tumor heterogeneity for the detection of features of the breast cancer (BC) pathogenesis.

Materials And Methods: Expression of estrogen receptors (ER), progesterone receptors (PR), Her2/neu, E- and N-cadherin, CD24, CD44, Bcl-2, Bax, Slug, P-gp, glutathione-S-transferase (GST) and metallothionein in cell lines was determined by the immunocytochemical method. Expression of ER, PR, Her2/neu, CD24 and CD44 in the surgical material of BC patients were determined by the immunohistochemical method.

[Radiofrequency ablation in combined treatment of metastatic colorectal liver cancer].

Aim: To study surgical and oncological outcomes in patients with metastatic colorectal liver cancer who underwent radiofrequency ablation in the structure of combined approach.

Material And Methods: It is a prospective analysis of treatment of 76 patients with metastatic colorectal liver cancer who underwent RFA for the period 2004-2013. Overall survival was analyzed using univariate and multivariate analysis.

Sequences of Landomycin E and Carotenoid Biosynthetic Gene Clusters, and Molecular Structure of Transcriptional Regulator of Streptomyces globisporus 1912.

Streptomyces globisporus 1912 and its derivatives 1912-2 and 1912-4Crt are the producers of the landomycin E, carotenoids and the regulator of antibiotics biosynthesis and morphogenesis of streptomycetes. The genome DNA of two mutant strains, 1912-2, the more effective producer of the landomycin E and the regulator, and 1912-4Crt, the producer of beta-carotene and lycopene, was sequenced by Illumina. Comparative analysis of the DNA sequences using GenBank data allowed localization of 36 landomycin E biosynthetic genes lnd of S.

Complex Identifcation of Red Yeast Isolate from Gastrointestinal Tract of Hucul Long-Liver (Carpathians, Ukraine).

The red yeasts are currently widely discussed and controversial group of yeasts because of the growing number of reports of their ability to become opportunistic pathogens of plants, animals and humans. The aim of this work was complex identifcation of the red yeast culture isolated from gastrointestinal tract of healthy Hucul long-liver from the Carpathians highland region of Ukraine. Torularhodin was found to be a major component within yeast culture carotenoids complex.

СD44+/CD24- markers of cancer stem cells in patients with breast cancer of different molecular subtypes.

Aim: To determine frequency of tumors with immunohistochemical markers of cancer stem cells (CSC) CD44+/CD24- in patients with breast cancer (BC) of different molecular subtype and to evaluate their prognostic value.

Object: Surgical material of 132 patients with BC stage I-II, age from 23 to 75 years, mean age - 50.2 ± 3.

The role of prognostic models in metastatic colorectal liver cancer surgery.

Introduction: Patients with metastatic colorectal liver cancer differ from each other by some characteristics which affect on the prognosis of disease. Long-term results and, consequently, the prognosis depend on not one but group of factors which may be incorporated into mathematical models allowing to classify patients according to their risk of recurrence or prognosis of survival.

Aim: To calculate survival in patients with metastatic colorectal liver cancer and to evaluate the most popular models of 3- and 5-year survival rate prognosis after liver resection.

[Associated liver partition and portal vein ligation for staged hepatectomy (ALPPS) - new opportunity in two-stage liver resection in patients with colorectal cancer metastases].

Major hepatic resection is often necessary for cure in patients with multiple colorectal cancer metastases but low future liver remnant (FLR) volume makes surgery risky because of the posthepatectomy liver failure (PHLF). Right portal vein ligation/embolization and two-stage hepatectomy were proposed previously to overcome this problem. Associated liver partition and portal vein ligation for staged hepatectomy (ALPPS) is a novel approach aimed for FLR volume hypertrophy.

Role of the hybrid Bcr/Abl kinase in the pathogenesis of chronic myeloid leukemia lacking C-Abl and CXCR4 proteins.

Philadelphia chromosome is a result of chromosomal rearrangement that leads to the appearing of the hybrid gene bcr/abl. A hybrid mRNA transcribes from bcr-promoter and many copies of hybrid molecules of Bcr/Abl protein are formed as a result of bcr/abl gene expression. It is supposed that a hybrid Abl molecule, replacing the normal one, in majority of cases functions abnormally or does not function at all.

[Genetic variability of synthesis feature of carotenoids in Streptomyces globisporus 1912].

Seventeen spontaneous and induced mutants, that acquired a new characteristic--the synthesis of beta-carotene and lycopene, were obtained from strain Streptomyces globisporus 1912. It was found that spontaneous mutants inherited more stably the acquired carotenogenesis as compared to induced ones. Synthesis of carotenoids by all isolated Crt+ Lcp+ cultures is a constitutive feature.

Isolation of Streptomyces globisporus and Blakeslea trispora mutants with increased carotenoid content.

Hyperpigmented mutants of Streptomyces globisporus 1912-Hp7 and Blakeslea trispora 18(+), 184(-) were isolated by action of hydrogen peroxide and nitrosoguanidine, correspondingly, from initial strains S. globisporus 1912-4Lcp and B. trispora 72(-), 198(+).

Significance of adhesion molecules expression for estimation of serous ovarian cancer prognosis.

Aim: To study the adhesion molecules CD44 and E-cadherin expression in serous ovarian cancer (OC) and their relationship with clinicopathological peculiarities of tumor process and prognosis.

Materials And Methods: The study was performed on OC samples from 72 patients with serous OC of stages I-III. Expression of CD44 and E-cadherin in tumor samples was evaluated with the use of immunohistochemical analysis.

[Features of biochemical changes in blood serum according to the form of progression of idiopathic and dysplastic coxarthrosis].

Carried out biochemical studies of blood serum (collagenase activity, glycosamineglicans and hydroxyproline fractions) of 72 patients with hip idiopathic osteoarthrosis and 30 patients with dysplastic osteoarthrosis of the iv-th stage in.accordance with J. H.

[Novel approach to two-stage hepatic surgery (in situ splitting)].

Two-stage liver surgery with preliminary right portal vein occlusion procedure (ligation or embolisation) became standard in clinical practice and allows liver resections in 60-82% of initially inoperable patients. Right portal vein ligation with concomitant liver partition in situ (in situ splitting, ISS) is innovatory and promising approach. Right portal vein ligation and in situ splitting was performed in 40 years old male with two metachronous rectal metastases in right liver lobe and insufficient volume of future liver remnant (22%).

[The surgical hepatology in SCS: from the beginning to development].

The article highlights survey stakes of surgical hepatology in world and Russia, and the 20 years experience of the Russian Scientific Center of Surgery named after B.V. Petrovskiy.

[Bacteriocidal activity of Streptomyces cultures].

Bacteriocidal activity of metabolites synthesized by 17 plasmid-containing cultures of Streptomyces has been studied. These cultures were isolated from soils of Ukraine with different anthropogenic contamination. The cultures, in their majority (85.

[Construction of a new bifunctional vector which contains EGFP-gene].

A number of bifunctional vector structures (pTpE, pTpE5, pTpH2, pTpH7, pTpS1) with molecular dimension of 11.3 kb has been created. Vector plasmids can be replicated, sustainably maintained and expressed both in Gram-negative (Escherichia coli XL1 Blue) and in Gram-positive (Streptomyces levoris 165) cultures.