Publications by authors named "Polina M Bogaychuk"
Article Synopsis
- * Our study analyzed data on genetic variants and Mendelian disease, finding that genes associated with multiple rare diseases are more constrained and usually express more transcripts across various tissues.
- * We found that while variant localization and type affect phenotype, they don't fully explain gene-disease relationships; further research is needed to understand other contributing factors to phenotypic heterogeneity.
Understanding the mechanisms underlying the connection between somatic mosaicism and cardiovascular disease is likely essential for the future of personalized medicine. This article is aimed at providing data on somatic mosaicism in human carotid atherosclerosis. An advanced carotid atherosclerotic plaque and white blood cells were collected simultaneously from each patient (eight Slavic males, aged 67 ± 3.
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