Fluorescence of radiation-induced tissue damage.

Purpose: The aim of this study was evaluating changes in the photosensitizer fluorescence in vivo in the radiation-induced damage area in comparison of intact areas with a simultaneous assessment of changes both in blood parameters and in histological data.

Materials And Methods: The study was conducted in white outbred SHK mice (n = 21). Their right hindlimbs were irradiated with a dose of 25 Gy after the intraperitoneal injections of photosensitizer 'Photosens'.