Publications by authors named "Poliana Guiomar de Almeida Brasiel"
Background & Aims: Cystic fibrosis (CF) is a multisystem disease that can compromise several human body organs. The autosomal recessive genetic disorder is caused by different mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) gene, responsible for chloride ion transport across apical membranes of epithelial cells in tissues and bicarbonate secretion. In this study, we provide a systematic review of the profile of the intestinal microbiota of cystic fibrosis individuals.
View Article and Find Full Text PDFObjective: To assess the clinical efficacy of flavonoid supplements on allergic diseases.
Design: Systematic review. .
Kefir modulates gut microbiota and reduces DMH-associated colorectal cancer via regulation of intestinal inflammation in adulthood offsprings programmed by neonatal overfeeding.
Food Res Int
February 2022
Obesity is associated with chronic inflammation, intestinal dysbiosis, and colorectal cancer risk. The anti-cancer effects of kefir are highlighted. Here, lactating Wistar rats were divided into: Normal litter (NL); Kefir normal litter (KNL); Small litter (SL); Kefir small litter (KSL).
View Article and Find Full Text PDFMaternal soy protein isolate diet during lactation programs deleterious effects on hepatic lipid metabolism, atherogenic indices, and function of adrenal in adult rat offspring.
J Dev Orig Health Dis
April 2022
Article Synopsis
- Soy consumption offers various health benefits, but its phytoestrogen content raises concerns during lactation and pregnancy, prompting a study on its cardiovascular effects on lactating rats and their offspring.
- Lactating rats were divided into groups based on diet (soy protein isolate, soybean, casein), revealing that both soy protein and soybean reduced atherogenic indices (cholesterol ratios) in offspring compared to the control group.
- While the soybean group's offspring showed lower oxidative stress, the soy protein isolate group had negative long-term effects, like increased liver cholesterol and worsened atherogenic indices in adulthood, suggesting caution in soy protein consumption during lactation.
Background & Aims: The COVID-19 infection can lead to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), mainly affecting patients aged 60 and older. Preliminary data suggest that the nutritional status can change the course of the infection, and on the matter, zinc is crucial for growth, development, and the maintenance of immune function. In the absence of treatment for this virus, there is an urgent need to find alternative methods that can contribute to control of disease.
View Article and Find Full Text PDFSoy consumption and its components, including its protein, are related to the beneficial effects of the lipid profile, decreased insulin resistance and glycaemia. However, the safety of the consumption of products containing phytoestrogens in critical stages of development has been questioned, since they may be associated with endocrine-metabolic dysfunctions in adult life. The purpose is to evaluate the effects of maternal dietary soy protein isolate (SPI) during lactation on the breast milk composition, body composition, lipid and glycaemic profiles, and thyroid hormones of dams and offspring at weaning (21 days) and in adulthood (150 days).
View Article and Find Full Text PDFPurpose: To evaluate the effects of maternal dietary soybean during lactation on the milk composition, body composition, lipid profile and glucose homeostasis of dams and offspring at weaning (21 days) and adulthood (150 days).
Methods: Lactating rats were divided into: casein control (C): casein diet; soy (S): soybean diet; soy oil control (SOC): casein diet, but with fat content similar to the S group.
Results: At 21 days, S mothers showed lower estradiol, total cholesterol (TC), low-density lipoprotein cholesterol (LDL) and triglycerides (TG) in serum; and lower TC and TG in milk.