Technological modeling of physicochemical removal of iron from deep groundwater.

In view of the significant difficulties arising in controlling the operation of the rapid iron removal filters on the basis of full exhaustion of their clarifying resource at every calculation stage (filter run), it is suggested to realize a simple control algorithm, which assumes an equal duration of filter runs during the entire service life of one filtering material change. Since the efficiency of physicochemical iron removal depends significantly on the specified duration, in order to establish its optimal value in every given case it is necessary to perform a special technical and economic analysis with a detailed consideration of the composition and degree of contamination of natural water. In the working conditions considered above, which are typical for physicochemical iron removal from deep groundwater in Ukraine, such a value was 600 conventional units, which corresponds to 48 h.

[The role of interphase prenucleolar bodies in the recovery of the nucleolar structure after reversible hypotonic treatment].

Interphase prenucleolar bodies are globular structures which accumulate in large numbers in the nucleoplasm of cultivated cells after hypotonic treatment and subsequent return to isotonic conditions; detailed studies of the role of these structures in the recovery of the nucleolus have not yet been performed. The limited mobility of interphase pronucleoli within the nucleus has been demonstrated. Exchange of the major nucleolar protein B23 between prenucleolar bodies and the surrounding nucleoplasm, rather than stable binding of this protein to the prenucleolar bodies, has been demonstrated using fluorescence recovery after photobleaching method.

[Structural-functional characteristics of cervical vessels in hypertensive patients under changed atmospheric pressure].

The ultrasonic location technique was used to measure intima-media thickness (IMT), as well as internal systolic diameter of and linear blood velocity in the cervical arteries in people with initial hypertension. Correlation analysis elicited a temporal contingency between these parameters and daily average values of atmospheric pressure. Thus, common carotid artery IMT tended to increase on high-pressure days.

[Significance of the individual helio-climatic factors in hemorrhagic fever with renal syndrome morbidity formation of population in the district of military units dislocation].

Been outlined the experience of mathematics modelling of natural phenomena for determination of the impact of individual factors and their combination on the epidemic process development. Found that 97,9% of the variation of haemorrhagic fever with renal syndrome index of population in the study area determine six climatic factors: the Wolf number, rainfall in November, the highest level of the river during floods, the temperature of air in October, the maximum and minimum levels of snow cover in February. As the most significant factors, contributing to the spread of the disease under study, been determine the parameters of air temperature and the height of snow.

[Experience of application of modern means of disinfection of air for preventive medications for respiratory diseases in troops].

Among factors of acute respiratory diseases morbidity in military personnel one of most important is frequent interfuisions, of military personnel and long-term occupancy in barracks in conditions of overcrowding. These factors conduce accumulation and communication of causative agents. Prophylaxis focused on prevention ofaerogenous transmission of infection.

[Assessment of diagnostic scales in cardiovascular patients being at home social service from the position of geriatric syndromes].

The obtained data, from a position of geriatric syndromes, testify to need of including of simple estimated scales of a self-rating of health and cognitive disorders in the program of inspection of the elderly patients being on home social service. The special attention in group of elderly patients with arterial hypertension should be paid to widowers who have a low self-rating of health.

[Optimization of nursing care in emergency cases in elderly patients residing in nursing homes].

The study analyzes data on the frequency of emergencies in elderly patients residing in nursing homes. We propose to introduce into the nursing care the screening phase of emergency conditions in elderly patients residing in nursing homes based on the selection of the leading symptom. This improves the quality of the nursing process in pre-hospital geriatric care in emergencies.

[Presence of Yersinia enterocolitica in conditions of agro complex].

Aim: Detection of duration of existence of Yersinia enterocolitica in substrates ofagro complex and formation of biofilms by causative agent during artificial semination of forage and meat products.

Materials And Methods: Y. enterocolitica 09 strain and its rifampicin-resistant (Rmr) mutant were used.

[Ischemic heart disease complicated by heart failure: possibilities of surgical treatment].

Aim of the study was to assess remote results of surgical reconstruction of the left ventricle (LV) in patients with ischemic heart disease (IHD) and chronic heart failure (CHF). During 1996-2010 136 patients with IHD complicated by CHD were subjected to surgery. The patients were divided into 2 groups: with LV aneurism (group 1, n=70) and with ischemic cardiomyopathy (group 2, n=66).

[Combined use conventional and videoendosurgery in pediatric oncology].

The autors report original date on the combined use of videosurgery and open surgical intervention in 3 patients. One (1 yr 10 mo) had neuroblastoma in the posterior mediastinum spreading to the retroperitoneal region, another (5 yr) presented with neuroblastoma in the thoracic aperture region spreading to the neck, the third one (14 yr) suffered limphoepithelioma-like cancer of the thymus. The combined treatment permits to optimize the surgical procedure and avoid additional use of thoraco- and laparotomy.

[Chromatin folding in human spermatozoa. I. Dynamics of chromatin remodelling in differentiating human spermatids].

Changes in chromatin structure at different stages of differentiation of human spermatids were studied. It was shown that, in nuclei of early spermatids, chromatin is loosely packed and its structural element is an 8-nm fiber. This "elementary" fiber is predominant at the initial stages of differentiation; in the course of maturation, it is replaced by globular elements approximately 60 nm in diameter.

[Experience of bicillin prevention of acute respiratory diseases in the training center].

The article describes the experience of emergency prevention of acute respiratory diseases among the young recruits by intramuscular injection of BICILLIN-5. This method allowed in winter 2011 to reduce the number of diseases caused by pneumococcus, staphylococcus and streptococcus significantly. Considering the polyetiology of pneumonia, acute bronchitis and acute respiratory infections, the lack of specific means of prevention against the majority of them, as well as the role of the low resistance of the organism in the military development of acute respiratory diseases, it is proposed to use antiviral drugs and immunotropic funds in addition to chemoprophylaxis and vaccination.

[Clinical, metabolic, age-related, and biorhythmologic aspects of daily arterial pressure profiles in patients with arterial hypertension].

The work was designed to study daily arterial pressure (AP) profile in 103 patients aged 20-70 (48.6 +/- 12.) years with grade I-II arterial hypertension and its relation to selected metabolic parameters, heliogeophysical factors and age.

[Permanent cardiac pacing in vasovagal syncope and carotid sinus syndrome].

Vasovagal syncope and carotid sinus syndrome are common conditions in young and elderly people, respectively, mostly with benign prognosis. Nevertheless, severe or "malignant" syncopal attacks in some patients may be associated with life-threatening injury. Unfortunately, up to now almost all drug trials have failed to demonstrate any benefit in preventing syncope and interventional approach (pacemaker) may be appropriate.

[Antipodal complex development in the embryo sac of wheat].

Dynamics of an antipodal complex formation in wheat (Triticum aestivum L.) has been observed in detail using a reconstruction of serial semifine sections. Three consecutive crucial stages have been identified in the development of the antipodal complex: (1) proliferation of initial cells, (2) growth and functional differentiation of antipodal cells, and (3) cell apoptosis.

[Nuclear matrix organization of the chromocenters in cultured murine fibroblasts].

In the current work, the structural organization of nuclear matrix of pericentromeric heterochromatin blocks (chromocenters) inside cultured murine fibroblasts was investigated. After 2 M NaCl extraction without DNase I treatment, chromocenters were extremely swelled, and it was impossible to detect them using conventional electron microscopy. Using immunogolding with anti-topoisomerase IIalpha antibody, we demonstrated that residual chromocenters were subdivided into numerous discrete aggregates.

[Histogenesis of infantile fibrosarcoma].

Eight cases of infantile deep soft tissue fibrosarcoma were examined. The tumor consists of neoplastic fibroblasts and myofibroblasts which differ from each other ultrastructurally. Well-differentiated collagen-forming neoplastic fibroblasts form one-half of infantile fibrosarcoma.

[Distributions of polymorphisms of genes of some components of hemostasis in patients with ischemic heart disease].

We have studied structure of polymorphisms of genes of blood clotting factors II, V, VII, platelet membrane glycoprotein IIIa (GPIIIa) and enzyme methylenetetrahydrofolate reductase (MTHFR) in patients with ischemic heart disease (IHD). In this cohort of patients most prevalent are polymorphism PLAA1/A2 of GPIIIa gene and 677T/T polymorphism of MTHFR gene. Inconsistency of existing evidence on effect of R/Q genotype of FVII gene on early development of IHD and myocardial infarction (MI) is underlined, and data on the absence of protective effect of Q allele on early development of MI are presented.

[The role of DNA methylation and histone modifications in structural maintainance of heterochromatin domains (chromocenters)].

The effects of DNA methylation inhibitor 5-azacytidine (5-aza-C) and histone acetylation inhibitor trichostatine A (TSA) on the structure of pericentric heterochromatin in cultured mouse cells (L929) has been studied. After 48 h of 5-aza-C treatment, about 85% of the cells demonstrate transformation of chromocenters from ovoid to elongated structures. Hypotonic treatment of these cells reveals tandemly arranged DAPI-positive globules, well distinguishable by light microscopy.

[Clinico-morphological peculiarities of thyroid cancer among children exposed to the Chernobyl disaster radiation].

The paper deals with a comparison of clinico-morphological patterns of sporadic thyroid cancer and that in pediatric patients exposed to radiation during the Chernobyl disaster. The latter are highly prone to both local and regional metastatic spread to the lymph nodes (intrathyroid distribution--61%; extension through capsule--42%, and metastases to the neck lymph nodes--66%). However, these data do not differ significantly from those for intact areas.

[Concerning study of life quality in patients with postinfarction cardiosclerosis].

Myocardial infarction, which often occurs as a result of emotional stress, represents a severe somatic disease. This disease creates a substantial stress which would affect the quality of patient's life. Other factors like age, gender and education level affect psychological condition of the patients who had previously suffered from myocardial infarction.

[Diagnosis of micrometastases of alveolar rhabdomyosarcoma].

Alveolar rhabgomyosarcoma is a highly malignant, small blue cell pediatric soft tissue tumor. Identification of micrometastases in alveolar rhabdomyosarcoma is important because the poor prognosis associated with this subgroup necessitates a modified therapeutic regimen. Since the obtained lymph node specimen can be very small; rhabdomyosarcoma cells are not easily detected using conventional histological methods.

[Chromatin structure within sites of DNA replication].

Conformational changes in chromatin structure are nowadays the object of intensive research due to its importance for proper regulation of intranuclear processes. The fine structure of chromatin within the DNA replication sites was studied in in situ fixed cells and cells permebilized by low ionic strength solutions in the presence of divalent cations. The latter method provides visualization of higher level chromatin structures such as globular chromomeres and chromonema fibres.