Using CFD simulations to investigate the shear stress in hydrodynamic cavitation reactors coupled with experimental validation using colony count measurements.

The current work investigates the shear stress distribution in hydrodynamic cavitation reactors with two different geometries using CFD simulations. Venturi type (positive geometry) and bore (negative geometry) were used to induce cavitation. Experimental validation of the predictions from simulations was also conducted by calculating the reduction rate in the colony count of Legionella pneumophila, a pathogenic bacterial strain.

Seed morphological traits as a tool to quantify variation maintained in collections: a case study in .

Understanding the within- and among-population distribution of trait variation within seed collections may provide a means to approximate standing genetic variation and inform plant conservation. This study aimed to estimate population- and family-level seed trait variability for existing seed collections of Torrey pine (), and to use these data to guide sampling of future collections. We quantified variation in 14 seed morphological traits and seedling emergence within and among Torrey pine populations.

Effect of hydrodynamic cavitation water treatment on Pseudomonas aeruginosa quorum-sensing molecules.

Hydrodynamic cavitation treatment was used for the functional inactivation of quorum-sensing lactone molecules of Pseudomonas aeruginosa. Hydroxyl radicals formed as well as the shear effects during the cavitation process induced the inactivation of the signal molecules through hydrolysis reaction coupled with bacterial destruction. Concentration of two different types of homoserine lactones (HSL) molecules was tested after the treatment at various rotational speeds.

How Community Organizations Promote Continuity of Care for Young People with Mental Health Problems.

Young people between the ages of 16 and 25 who experience mental health problems experience transitions and need help from a variety of organizations. Organizations promote continuity of care by assisting young adults with developmental, service, and systemic transitions. Providers offer specific services to help transitions and also form cooperative relationships with other community organizations.

Immediate effects of spinal manipulative therapy on regional antinociceptive effects in myofascial tissues in healthy young adults.

Objective: The purpose of this study was to investigate if spinal manipulative therapy (SMT) can evoke immediate regional antinociceptive effects in myofascial tissues by increasing pressure pain thresholds (PPTs) over myofascial trigger points in healthy young adults.

Methods: A total of 36 participants (19 men, 17 women; age, 28.0 [5.

Incidence, Paris classification, and follow-up in a nationwide incident cohort of pediatric patients with inflammatory bowel disease.

Objectives: The aim of the study was to evaluate the incidence, baseline disease characteristics, and disease location based on the Paris classification in pediatric inflammatory bowel disease (IBD) in the Hungarian nationwide inception cohort. In addition, 1-year follow-up with therapy was analyzed.

Methods: From January 1, 2007 to December 31, 2009, newly diagnosed pediatric patients with IBD were prospectively registered.

Using a bicycle-pedestrian count to assess active living in downtown Wilkes-Barre.

Background: Downtown Wilkes-Barre, a town of 40,000 residents in Northeast Pennsylvania, and the hub of a planned urban, suburban, and rural trail network, was the site of a number of changes to improve walkability during the Active Living by Design (ALbD) grant period.

Purpose: The Wyoming Valley Wellness Trails Partnership and Greater Wilkes-Barre Chamber of Business and Industry initiated the Wilkes-Barre Downtown Bicycle and Pedestrian Count (Bike-Ped Count) in order to pilot bicycle and pedestrian counting methods and to evaluate downtown built environment and policy changes.

Methods: The Bike-Ped Count was conducted during nine 2-hour counting periods over 4 days in September using screen-line count methods at seven locations downtown and at River Common Park.

Pancreatic autoantibodies and autoantibodies against goblet cells in pediatric patients with inflammatory bowel disease.

Background: Significance of pancreatic autoantibodies determined by using exocrine pancreas (PAB) and antibodies against recombinant pancreas antigen (rPAB), as well as the importance of autoantibodies against goblet cells (GAB), is not known in pediatric patients with inflammatory bowel disease (IBD). Our aim was to determine the complex analysis of PAB, rPAB, GAB, antibodies against Saccharomyces cerevisiae, and perinuclear components of neutrophils in pediatric patients with IBD. Moreover, association with NOD2/CARD15 and disease phenotype was determined.

[Analysis of infliximab treated pediatric patients with Crohn disease in Hungary].

Infliximab, the chimeric antibody to tumor necrosis factor-alpha, is indicated for medically refractory pediatric Crohn disease. Aim of our study was to examine the efficacy and side effects of infliximab therapy in Hungarian pediatric patients with Crohn disease since the authorisation of medicine for children to 31.12.

Promoting and developing a trail network across suburban, rural, and urban communities.

Background: The Wyoming Valley Wellness Trails Partnership received an Active Living by Design grant late in 2003 for a project centered on a growing trail network linking urban, suburban, and rural communities in northeast Pennsylvania, a former coal region, in order to increase physical activity among residents.

Intervention: The partnership conducted research, collected information, created promotional documents, worked with partners on events and programs, and participated in trail planning. Local trail organizations continued planning and construction toward developing a trail network.

Parenting adults who become homeless: variations in stress and social support.

This article focuses on the stressors of parenting an adult child who experiences homelessness. Parents whose adult children become homeless may provide support to this child, but they may also subsequently experience stress and require social support themselves. Findings from this study support the hypothesis that parents who spend more time or money helping their homeless adult offspring experience higher levels of stress.

Organizational context and provider perception as determinants of mental health service use.

This study refines and tests an individual client model of service use and contrasts it with a model of service provision based on gateway provider perspectives. Structural equation models demonstrate that provider variables account for more service use variation than client variables. The client model accounts for 24% of the variance in service use, while the provider model accounts for 55% of the variance.

New patterns of community care: coordinated services for dually diagnosed adults in North Carolina.

North Carolina has developed coordinated care systems for people dually diagnosed with both a mental retardation and a different major mental illness. In response to a class action lawsuit, the state has become a leader in treatment of this form of dual diagnosis. Systems of care for this "Thomas S class" operate in each of 41 area programs for mental health, developmental disabilities, and substance abuse.

Youths' access to mental health services: the role of providers' training, resource connectivity, and assessment of need.

This paper posits that providers with training in and knowledge of mental health resources are more likely to recognize youths' mental health problems, and provide youths with services. In 1994 and 1996, we interviewed 792 adolescents who were involved with St. Louis public health, juvenile justice, child welfare.

Effect of methionine enrichment on the biological activities of food proteins.

A special enzymatic technique, the enzymatic peptide modification (EPM) reactions have been worked out in our laboratory, by which proteins can be modified with respect to their biological activities. Enzymatic modification methods provide several advantages in producing proteins of desired nutritional properties. Proteolytic modification, particularly when combined with methionine enrichment, significantly altered the biological activities and leads to increased nutritional value.

HM-PAO-labeled leukocyte scintigraphy in pediatric patients with inflammatory bowel disease.

Leukocyte scintigraphy (LS) was performed in 20 pediatric patients with inflammatory bowel disease (IBD: 10 with ulcerative colitis, 2 with indeterminate colitis, and 8 with Crohn disease) in different stages of clinical activity. Leukocytes were separated from 15 to 60 ml venous blood and were labeled in vitro with [99mTc]HM-PAO. The segmental extent (small intestine; ascending, transverse, and descending colon; and recto-sigmoideum) of the process was determined by LS.

HIV-risk behavior among lesbians and bisexual women.

Although limited available data suggest that AIDS is currently less common among lesbians than among heterosexual women, this study suggests considerable HIV-risk behavior among our sample of lesbians and bisexual women. In addition, a majority of respondents, including women at risk, do not use safer-sex practices.

[Long-term follow up study of children with celiac disease].

27 long term monitored coeliac children were assessed. The average length of follow-up was 6.4 years, the average age of the children was 11.

Pharmacokinetics of vinpocetine and its main metabolite apovincaminic acid before and after the chronic oral administration of vinpocetine to humans.

The pharmacokinetics of vinpocetine (Cavinton) and of its main metabolite apovincaminic acid (AVA), has been studied in 5 healthy male volunteers after the administration of 3 x 5 and 3 x 10 daily doses of vinpocetine for seven days. The pharmacokinetic curves of both vinpocetine and AVA have been determined prior to the chronic administration and on the last day of the treatment, whereas between the 2nd and 6th days, concentration was measured once daily. On the basis of these pharmacokinetic studies it can be concluded that both vinpocetine and AVA show linear pharmacokinetics at the doses used and that there is no accumulation or autoinduction.

[Demonstration of antibodies against gliadin using an immunofluorescence method in childhood celiac disease].

IgA and IgG type antibodies against gliadin were demonstrated in 396 serum samples of 350 patients with immunofluorescence method. The procedure was used in cases of clinically suspected celiac disease and for the control of the diet of patients with diagnosed celiac disease. The sensitivity of the patient material was 83% in the case of antibodies against IgA and 85% with antibodies against IgG.

Pharmacokinetics of vinpocetine and its metabolite, apovincaminic acid, in plasma and cerebrospinal fluid after intravenous infusion.

The pharmacokinetics of vinpocetine (ethyl apovincaminate, Cavinton) and its metabolite, apovincaminic acid, was studied in patients with cerebrovascular disorders. Vinpocetine (1 mg/kg) was infused intravenously over 25 min. The elimination half-life of the parent drug in plasma was 4.

Pharmacokinetics of vinpocetine (Cavinton) in dog.

The pharmacokinetics of vinpocetine after 10 mg po and iv doses was studied in six beagle dogs treated in cross-over design. The concentration of the drug in plasma was determined by gas-liquid chromatography using N-P FID and capillary column. The elimination half-live and clearance values calculated from time plasma concentration data for iv administration were 8.