Publications by authors named "Pol Molina"
Article Synopsis
- Bilastine is a non-sedating antihistamine effective for treating allergies, and this study aimed to compare its different formulations (i.v., i.m., and oral) against dexchlorpheniramine and placebo for their antihistamine activity and onset time.
- Conducted on 25 healthy adults, the study demonstrated that all bilastine formulations provided quick relief (15 min for i.v. and i.m., 30 min for oral) and significantly reduced allergic reactions compared to dexchlorpheniramine and placebo.
- The results showed that bilastine formulations were not only more effective but also safe, with no serious adverse events reported, while dexchlorpheniramine was
Lack of Clinical Relevance of Bilastine-Food Interaction in Healthy Volunteers: A Wheal and Flare Study.
Int Arch Allergy Immunol
December 2022
Article Synopsis
- The study compared how food affects the pharmacodynamic activity of bilastine in healthy volunteers, showing that food impacts bilastine levels but not its effectiveness.
- Under both fasting and fed conditions, bilastine showed a decrease in blood concentration levels, but the antihistamine's effect remained consistent.
- Even with a slight delay in action when taken with food, bilastine's overall clinical efficacy was unaffected.