[Use of fish oil enriched with carotenoids isolated from sea cucumbers in the diet therapy of patients with hypertension and ischemic heart disease].

Usage of antisclerotic diet with fish oil and carotinoides in patients with IND and high blood pressure resulted in positive dynamic of clinic manifestation, blood lipid, coagulogramms, antioxygen and immune status.

[Influence of bioactive dietary supplement--dietary unsaturated fats--on immune status of patients with myocardial ischemia and impaired glucose tolerance].

Immune status measured by the flow cytrometric analysis under the ischemic heart disease and IHD with impaired glucose tolerance has been found to be altered in B cells as well as in T lymphocytes in some cases. Having received the diet supplemented by PUFA "Eicolen", IHD patients present with the restored immune status. Patients with IHD and impaired glucose tolerance did not present with any significant modifications in immune status after PUFA "Eicolen" supplementation.

[Correction of mineral metabolism impairment with an allowance for seasonal fluctuations in patients with ischemic heart disease and hypertensive disease with overweight].

The influence of antiaterosclerotic diet with including some biologically active supplements (BAS), containing Zn, Mg, Na, K, Ca, vit C, E, B2, B6, beta-carotene, I was studied in 164 patients with ischemic heart disease and hypertension disease. BAS has been use with an allowance for seasonal fluctuations of microelements sufficiency. The usage of BAS "Lifepack" has priority in spring.

[Dietetic canned food using ocean fish and plant components].

The results of the creating canned ground goods of a new kind are described in this article. The main character references of food value of hake and the canned ground foods based on it. It has been established that the new products of safety.

[Clinical-metabolic evaluation of the effectiveness of the olive oil use in patients with cardiovascular diseases].

Investigation of influence of diet with olive oil on clinical, metabolic and immune indices in patients with ischemic heart disease and hypertension was conducted. As a result of the diet modified by the lipid component positive effect on the course of the diseases and lipid spectrum of blood, pronounced action on some indices of cell immunity, intensity of processes of lipid peroxidation were observed.

[Effects of antiatherosclerosis diet including soy protein on the dynamics of clinical, biochemical and immunologic indicators in patients with ischemic heart disease and hypertension].

Investigation of influence of diet with soy-protein on clinical and immune indices in patients with ischemic heart disease and hypertension was conducted. As a result of the diet modified by the protein component positive effect on the course of the diseases and lipid spectrum of blood, pronounced action on some indices of humoral immunity, intensity of processes of lipid peroxidation were observed.

[Juices in therapeutic-prophylactic nutrition].

The main aspects of using juices with therapeutic and prophylactic purposes are demonstrated. Multifactorial influence of vegetable and fruit juices on the organism, primarily depends on their chemical composition. The necessity of their differentiated use basing not only nosological unity, but also on the degree of functional and metabolic disorders taking place in certain pathology is emphasized.

[Clinical and metabolic effects of biological active food additives--phospholipids--in patients with cardiovascular diseases].

Uses of new phospholipid-containing food supplement 'Tonus' in patients with ischemic heart disease, hyperlipoproteinemia or hypertension during 4 weeks promoted positive changes clinical symptoms of diseases against a background of lowering of serum cholesterol, triglycerides and increasing of HDLP-cholesterol and improving liver function.

[The effect of vitamin- and beta-carotene-enriched products on the vitamin A allowance and the concentration of different carotenoids of the blood serum in victims of the accident at the Chernobyl Atomic Electric Power Station].

The results of clinical trials of efficiency of foods enriched by vitamins and beta-carotene in people suffered from Chernobyl's accident are presented. The level of beta-carotene in clinical diets was the same during trial. Daily consumption of enriched food supplying ingestion of 4-5 mg of beta-carotene increased the level of beta-carotene in serum by 2-4 times.

[Effects of diet containing polyunsaturated fatty acids omega-3 and different doses of vitamin E on the activity of lipid peroxidation in patients with hypertension].

Change in lipid peroxidation processes (POL) have been studied in 32 patient with II degree hypertension disease after treatment by diet containing 20 g fish oil (eiconol) and 12.5 or 125 mg of vitamin E. The treatment with diet containing high level of PUFA did not cause increasing activity of POL.

[The antioxidant defense system in hypertension patients on a diet enriched with omega 3 polyunsaturated fatty acids and alpha-tocopherol].

A state of the anti-oxidation system in blood and the rate of lipid peroxidation were studied in patients with hypertension. High sensitivity of the anti-oxidation system enzymes to alterations in the diet fat composition was detected in the patients, nutrition of whom was evaluated in detail. Excessive doses of alpha-tocopherol, added to the diet enriched with omega 3-polyunsaturated fatty acids normalized lipid peroxidation and stabilized the enzyme activity involved in the anti-oxidation system.

[Characteristics of the humoral immune system and lipid peroxidation processes in people living in territories contaminated with radionuclides].

Among 33 patients with Stage II hypertension, 25 persons were inhabitants of the Russian radionuclide-contaminated areas and 8 patients had no prior contacts with ionizing radiation (control). All the patients examined were maintained within 4 weeks on a diet, radioprotective effect of which was realized due to the elevated content of sulfur containing amino acids, antioxidants and complexes. In the patients who lived in the radionuclide-contaminated areas, a moderate activation of lipid peroxidation was detected simultaneously with marked alterations in the humoral component of the immunity system, which involved a considerable increase in the levels of IgG and complements C3 and C4.

[The antimicrobial properties of metals and coatings for medical articles].

The in vitro experimental studies have shown that samples coated with vacuum technology-made materials, such as titanium mixtures with chromium, hafnium, zirconium, and copper have antimicrobial properties against staphylococci, Escherichia coli, Proteus, Pseudomonas aeruginosa. The impact of the coatings on bacterial cells is selective and ambiguous.

[Effect of anti-arteriosclerosis diet, containing soya protein isolate and omega-3 polyunsaturated fatty acids on the activity of mononuclear and platelet lysosomal hydrolases in patients with hypertension and ischemic heart disease].

In response to antiatherosclerosis dietotherapy containing 20 g of ichthyenic oil, coronary and hypertensive subjects showed lowered serum levels of cholesterol, triglycerides and atherogenic index, elevated HDLP cholesterol and corrected immunochemical shifts. SPI-containing diet resulted in changes of CIC IgM levels only. Shifts in the activity of mononuclear and platelet lysosomal hydrolases which occurred in the above patients due to relevant diets reflect higher sensitivity of this parameter in assessment of the dietotherapy effectiveness.

[The effect of a soy protein isolate and sources of polyunsaturated omega-3 fatty acids in an anti-atherosclerotic diet on the lipid spectrum of blood serum and immunological indicators in patients with ischemic heart disease and hypertension].

Blood serum lipid spectra and immunologic spectra were studied in patients with ischemic heart disease and hypertension maintained on antiatherosclerotic diet containing either soy bean protein isolates or ichthyenic oil. The ichthyenic oil-containing diet decreased distinctly the level of cholesterol, triglycerides and the atherogenicity coefficient simultaneously with an increase of cholesterol content in high density lipoproteins in blood of 37 patients with these diseases. The diet with soy bean protein isolates exhibited less pronounced effects on lipid metabolism patterns in blood serum as compared with the ichthyenic oil-containing diet; however, the former diet contributed to normalization of the immunologic reactions in patients with ischemic heart disease and hypertension.

[The effect of dietotherapy on the clinico-immunological indices of rheumatoid arthritis patients].

The main requirements for the dietotherapy of rheumatoid arthritis (RA) patients have been formulated, and for the first time a pathogenetically balanced diet has been developed that produces antiinflammatory and immunocorrective effects. The effectiveness of the dietotherapy included into the combined treatment was studied in 41 patients with classic and proved RA. The authors have studied the influence of the dietotherapy on the clinical signs characterizing the activity of inflammation in the joints, and laboratory immunological parameters (IgG, IgM, IgA, IgD, the complement components: C1-inhibitor, C3, C4, C5, C9; haptoglobin, orrhozomucoid, transferrin, ceruloplasmin, alpha 1-antitrypsin, alpha 2-macroglobulin, prealbumin).

[Anti-atherosclerotic properties of some components of food (a clinico-experimental study)].

Platelet lysosomal proteinase and phospholipase activity, cholesterol content in the blood serum and circulating immune complexes, as well as blood serum atherogenic potential were studied with the use of human aortal intima atherosclerotic cell culture in patients with postinfarction cardiosclerosis (males aged from 45 to 62 years), 1-3 h before and 2-6 h after a single intake of one of the following products (50 g): sunflower oil, butter, cod fat, glucose, fructose, starch, dried milk protein, or 22 g of soybean protein isolate 500 U. The total data obtained have evidenced that the soybean protein isolate produces hypolipidemic and hypocholesterolemic effects, as well as possesses pronounced anti-atherosclerotic properties.

[Characteristics of water-electrolyte balance in patients with labile essential hypertension and various approaches to the optimal therapy with diuretics and low-sodium diet].

A study of 56 males, aged 22 to 56 years, with uncomplicated essential hypertension, stages IB-IIA, where pretreatment examination was followed by repeat investigation after 4 or 5 weeks of treatment with diuretics or low-sodium diets with strict (less than 2 g), moderate (up to 3 g), or mild (4-4.5 g) restriction of sodium uptake, demonstrated a tendency to sodium retention with fluid redistribution from the interstitium to intravascular space in the presence of diuretic treatment. Where dietary sodium was reduced, extracellular sodium was increased owing to increased residual sodium, while total metabolic sodium dropped, and extracellular fluid increased owing to the increase in interstitial fluid.

[Nutrition factor in the treatment and prevention of ischemic heart disease under ambulatory care].

Study of the influence of a long-term staged use of diet therapy during prophylactic medical observation of post-myocardial infarction patients has shown that the anti-sclerosis diet used under clinical conditions was effective for relieving the angina pectoris syndrome and obtaining favourable dynamic changes in a number of metabolic parameters. Among the out-patients the diet was used by only 76 per cent. A comparative study of the results of diet therapy during the 3-year medical observation has shown a clear tendency to a gradual reduction of hyperlipoproteinemia and excessive body weight in patients who adhered to the diet.

[Effect of pectin on indices of lipid and carbohydrate metabolism in patients with ischemic heart disease].

The influence of the diet containing 10 g of citrus pectin, made by "Copenhagen-Pectin-Fabric", on some parameters of lipid and carbohydrate metabolism was studied in 33 coronary heart disease male patients, aged from 29 to 40 years, who had survived documented myocardial infarction. The results of the investigation have evidenced that increased pectin content in the diet promotes the reduction of the total cholesterol and triglyceride levels in the blood serum, the rise of tolerance to carbohydrates and produces no appreciable effect on the lithogenic potential of bile in the coronary patients.