Dental maturation in children with shunt-treated hydrocephalus.

Objective: The aim of this study was to examine the relationship between dental maturation and somatic development and to discover their possible deviations in children with shunt-treated hydrocephalus.

Design: Radiographs (orthopantomogram and hand-wrist radiograph) from children with shunt-treated hydrocephalus were analyzed with respect to the dental maturation and compared with values of an age- and sex-matched control group and population standards.

Patients: Forty-one children with shunt-treated hydrocephalus (27 boys and 14 girls) aged from 5 to 16 years (median age 11.

Comparison of amounts and properties of collagen and proteoglycans in condylar, costal and nasal cartilages.

In this study we compared the compositions of extracellular matrices of condylar, costal and nasal cartilages to characterize differences in growth patterns in relation to matrix composition. Condylar, costal and nasal cartilages of 25- and 35-day-old rabbits were extracted and subjected to bio- and histochemical analysis to determine total amounts of collagen and amounts and aggregating properties of proteoglycans. We found that proteoglycan content and aggregate formation were greatest in nasal cartilage, and lower in costal and markedly lower in condylar cartilage.

Unilateral masticatory function changes the proteoglycan content of mandibular condylar cartilage in rabbit.

Unilateral masticatory function was induced in 10-day-old rabbits by grinding the right side molars out of occlusion under general anesthesia. The grinding procedure was repeated twice a week thereafter. They were killed at the ages of 25 and 35 days.

Location of the glenoid fossa after a period of unilateral masticatory function in young rabbits.

Changes in glenoid fossa position and skull morphology after a period of unilateral masticatory function were studied. The right-side maxillary and mandibular molars in twenty-seven 10-day-old rabbits were ground down under general anaesthesia. The procedure was repeated twice a week, until the rabbits were 50 days old.

Craniofacial growth after a period of unilateral masticatory function in young rabbits.

Changes in craniofacial growth after a period of unilateral masticatory function were studied in rabbits. 10-day-old animals were divided into 3 groups. In Group I, mandibular and maxillary molars were ground down 2x a week on the right side under general anesthesia until age 50 days, and were thereafter left to grow without grinding.

Pituitary size and function in children and adolescents with shunted hydrocephalus.

Objective: Most previous reports of endocrine disorders in children with shunted hydrocephalus have been case reports and there is a lack of systematic information on pituitary anatomy and function among these children. We have obtained these data in a large group of individuals with shunted hydrocephalus.

Design: A controlled cross-sectional study.

Growth and type-II collagen expression in the glenoid fossa of the temporomandibular joint during altered loading: a study in the rat.

The aim of this study was to measure changes in growth of the glenoid fossa and its articular eminence after decreased loading. A further aim was to evaluate the role of mechanical forces in relation to the existence of a cartilage layer, by determining type-II collagen secretion. A total of 99 Wistar rats were used: 48 animals were fed whole pellets and 51 were fed ground pellets.

Effect of unilateral masticatory function on craniofacial growth in the rabbit.

In this study the main purpose was to investigate the effect of altered masticatory function on the shape and inclination of the articular surface of the glenoid fossa, and on the growth of the mandible in the rabbit. The maxillary and mandibular molars of 14, 10-d-old rabbits were ground down to the gingiva on the right side twice a week; 9 were controls. At age 50 d all rabbits were killed, soft tissue of the heads was removed, and the measurements were made.

Glycosaminoglycan synthesis in the mandibular condyle during growth adaptation.

Condylar growth was studied after an operation simulating functional orthodontic appliances. Twenty-five rabbits underwent a surgical operation for the induction of premature synostosis to displace the glenoid fossa posteriorly during growth. Twenty-five control rabbits underwent sham operations.