[Magnesium and cardiovascular disease: new data and perspectives].

Presented data are intended to draw the attention of clinicians to question the importance of timely diagnosis deficiency of magnesium states and their timely correction of both patients by providing dietary guidelines and prescribing magnesium for preventive and therapy purposes.

[Depressive symptoms worsen cardiovascular prognosis and shorten length of life in patients with arterial hypertension and ischemic heart disease].

Unlabelled: The KOORDINATA study (clinical epidemiological program of investigation of depression in cardiological practice in patients with arterial hypertension and ischemic heart disease) was a prospective 3 year long multicenter study of effects of depressive and anxiety states on the course and prognosis of ischemic heart disease (IHD) and arterial hypertension (AH).

Material And Methods: Patients (n=5038, age more or equal 55 years) with verified IHD and/or AH from 37 cities were included into the study. Symptoms of anxiety and depression were assessed by the HADS scale (Hospital Anxiety And Depression Scale) validated in Russia.

Hypertensives in Russia are interested in a healthier lifestyle: results of the RELIF multicenter study.

Background: There are several reasons for the gap between guidelines and routine practice of cardiovascular disease (CVD) prevention. Among these patient-related factors are interest and motivation for lifestyle modification.

Design: The article represents a subgroup analysis of RELIF (REgularnoe Lechenie I proFilaktika) study conducted in 20 cities of Russia, where five polyclinics were selected randomly, with five general practitioners (GPs) in each.

[Efficacy of an educational preventive technology in patients with stable angina in ambulatory conditions].

Aim of the study was to assess efficacy of educational technology--School for patients with stable angina--in conditions of practical health care. We randomized 100 patients with ischemic heart disease (IHD) and stable FC I-III angina into 2 groups one of which went through learning in a School for patients with IHD (6 90 min sessions 2 times a week). Patients of both main and control groups were followed up for 12 months.

[RELIPH - regular treatment and prevention - the key to improvement of situation with cardiovascular diseases in Russia: results of a Russian multicenter study (part III)].

The first results of a big Russian multicenter study " RELIF - Regular treatment and prevention - the key of improvement of the situation with cardiovascular diseases in Russia " are presented. The study examines the accordance of arterial hypertension (AH) and coronary heart disease (CHD) treatment recommended by physicians to contemporary standards. Patients adherence to physicians recommendations is also studied.

[RELIPH -- REgularnoye Letcheniye I ProPHylaktika (Regular Treatment and Prevention) -- the key to improvement of situation with cardiovascular diseases in Russia: results of multicenter study. Part II].

The paper presents results of the conducted in Russia large scale study " REgularnoye Letcheniye I ProPHylaktika (Regular Treatment and Prevention) -- the key to improvement of situation with cardiovascular diseases in Russia -- RELIPH " on assessment of conformity of recommended by medical practitioners treatment of arterial hypertension (AH) and ischemic heart disease (IHD) to contemporary standards as well as compliance of patients to physician s recommendations. Local physicians/general practitioners (n=512) and patients (n=2517) with AH (isolated and combined with IHD) from 20 cities in Russia participated in the study. This publication contains data on assessment of compliance of patients to antihypertensive therapy and to recommendations of physicians concerning non-drug treatment, as well as analysis of large number of factors closely associated with compliance.

[Depressive symptoms worsen prognosis in patients with arterial hypertension and ischemic heart disease: first results of prospective phase of Russian multicenter study COORDINATA].

COORDINATA - Russian multicenter prospective (3 year long) study having the aim to elucidate influence of symptoms of anxiety and depression on cardiovascular (CV) prognosis in patients with arterial hypertension (AH) and ischemic heart disease (IHD). Results of 1.5 years of prospective phase of the study are presented.

[RELIPH--REgularnoye Letcheniye I ProPHylaktika (regular treatment and prevention)--the key to improvement of situation with cardiovascular diseases in Russia: results of multicenter study. Part I].

The paper presents first results of the conducted in Russia large-scale study " REgularnoye Letcheniye I ProPHylaktika (Regular Treatment and Prevention)--the key to improvement of situation with cardiovascular diseases in Russia--RELIPH" on assessment of conformity of recommended by medical practitioners treatment of arterial hypertension (AH) and ischemic heart disease (IHD) to contemporary standards and compliance of patients to physician's recommendations. Local physicians/general practitioners (n=512) and their patients (n=2517) with AH and IHD from 20 cities of Russia participated in the study. The publication contains data on prevalence of risk factors in patients with AH and IHD, their knowledge, habits, skills, and amount of possessed medical information, as well as awareness of primary care physicians about actual problems of secondary prevention of cardiovascular diseases.

[Compliance to treatment of arterial hypertension and ischemic heart disease - key condition of lowering of cardiovascular mortality].

The paper contains consideration of the problem of compliance to treatment of arterial hypertension and ischemic heart disease. Various aspects of compliance to treatment related to patients, physicians, special features of diseases and character of drug and nondrug recommendations.

[Clinico-epidemiological program of the study of depression in cardiological practice in patients with arterial hypertension and ischemic heart disease (COORDINATA)].

Unlabelled: COORDINATA - first Russian multicenter prospective (3 year long) study having the aim to elucidate prevalence of symptoms of anxiety and depression among patients with arterial hypertension (AH) and ischemic heart disease (IHD) and their influence on cardiovascular (CV) prognosis. Results of baseline epidemiological part of the study are presented. Results of prospective phase will be published in 2008.

[ Psychological stress and acknowledgement of its value as a first order cardiovascular risk factor].

The paper contains analysis of results of recent studies of relationships between stress and cardiovascular morbidity and mortality. A variety of stress reactions are depicted: acute stress, chronic stress, as well as models of work stress. Pathophysiologic mechanisms of links between stress and cardiovascular morbidity and mortality are discussed, and most effective methods of correction of elevated levels of stress and their clinical and prognostic value for treatment of ischemic heart disease are presented.

[Depression in cardiological practice: pilot results from a multicenter clinico-epidemiological trial in hypertensive patients with ischemic heart disease (koordinata)].

Aim: To study effects of depression on the course and prognosis of arterial hypertension (AH) and coronary heart disease (CHD), potentialities of the combined treatment in a prospective multicenter trial.

Material And Methods: A total of 376 patients with AH and/or CHD having depression (10 scores and higher by HADS scale) were assigned to two groups: 189 (50.3%) patients received somatotropic therapy+coaxil (the study group), 187 (49.

[Rehabilitation of patients with ischemic heart disease at outpatient stage.].

The article is assigned to general practitioners and devoted to the outpatient combined rehabilitation of coronary heart disease patients, including those after myocardial infarction. In the part concerning the physical rehabilitation there is given the classification of patients by functional classes, the exercise programs of middle intensity for sport and home training. The formula of selection of the walking training temp according to the results of exercise stress test is given.

[Clinical efficacy of tianeptine in patients with ischemic heart disease and comorbid depression].

Ischemic heart disease patients (20 men, 20 women, age 36-72 years) with class II-III effort angina and depression (Beck Depression Inventory -- BDI -- score > or = 19) were randomized to standard therapy were treatment of stable ischemic heart disease (control group) or standard therapy plus tianeptine 37.5 mg/day. After 6 weeks 52% decrease of BDI score occurred in tianeptine treated patients (from 24.

[Clinical efficacy of citalopram in patients with hypertension and concomitant depression].

Patients (n=28) with mild to moderate hypertension and depression were given enalapril (20 mg/day). If target blood pressure was not achieved in 10 days hydrochlorothiazide (12.5 mg/day) was added.