[Survival of probiotic microorganisms in the conditions in vitro imitating the process of human digestion].

Purpose Of The Study: Assessment of survival bifidobacteria and lactobacteria under the conditions in vitro, simulating digestion in human stomach and intestine, and study of survival probiotic and indigenous microorganisms in co-cultivation on solid nutrient medium.

Materials And Methods: Probiotic microorganisms from commercial preparations Bifidobacterin and Lactobacterin, clinical isolates lactobacillus (Lactobacillus acidophilus No 1, L. brevis No 2) were used in experiments.

[Experimental study of sensitivity of probiotic microorganisms to antibacterial drugs].

Purpose Of The Study: Investigation of sensitivity of probiotic microorganisms to antibacterial drugs.

Materials And Methods: Probiotic microorganisms from domestic and foreign commercial preparations were used in experiments. The study of sensitivity of probiotic microorganisms to antibacterial drugs was carried out using solid nutrient medium containing calculated amount of antibacterial drugs.

[Comparative assessment of survival of probiotic microorganisms from commercial preparations under the conditions in vitro].

Purpose Of The Study: Assessment of survival of probiotic microorganisms from commercial preparations under the conditions in vitro simulates digestion in human stomach and intestine.

Materials And Methods: Probiotic microorganisms from domestic and foreign commercial preparations were used in experiments. Study of survival of probiotic microorganisms was carried out on the model in vitro simulates the conditions of digestion in the human body.

[Evaluation of the protection efficiency of secretory antibodies in experimental Yersinia infection in guinea-pigs immunized with polyvalent vaccine against this infection].

The paper presents the results of experiments to elucidate the protection efficiency of secretory antibodies via parenteral and oral inoculation with pathogenic Yersinia in guinea pigs immunized with a polyvalent yersiniasis vaccine designed on the basis of the pseudotuberculosis microbial strain that synthesizes the F1 antigen of a plague microbe. Immunization of guinea pigs with the polyvalent yersiniasis vaccine protects experimental animals against pseudotuberculosis, intestinal yersiniasis, and plague infections.

[Temperate Legionella bacteriophage: discovery and characteristics].

For the first time, temperate Legionella bacteriophage was isolated from organs of guinea pig infected with Philadelphia 1 strain of Legionella pneumophila. Negative colonies of bactriophage from 1.5 to 2.

[The role of the Yersinia plasmid of calcium-dependency in the formation of the plague immunity].

It was shown that viable variants of the Y. enterocolitica microorganisms containing the plasmid of Ca-dependency (native one or from EV/ I Y. pestis cells) were more immunogenic to plague-infected guinea pigs than isogenic non-plasmid variant.

[The antibody spectrum after the inoculation of sensitive animals with Yersinia pestis and Yersinia pseudotuberculosis bacteria].

Antibody spectra in the sera of guinea pigs and white mice infected with Y. pestis and Y. pseudotuberculosis, the causative agents of plague and pseudotuberculosis, were determined with the use of immunoblotting.