Publications by authors named "Poey N"
Tularemia in Pediatric Patients: A Case Series and Review of the Literature.
Pediatr Infect Dis J
September 2024
Article Synopsis
- Tularemia is often misdiagnosed in children due to its similar symptoms to other common lymphadenopathy diseases, leading to delayed treatment; awareness among pediatricians is crucial.
- A review of 94 cases revealed a wide age range of affected children, with infection sources primarily from zoonotic transmission and contaminated water, and fever being a common symptom.
- Effective treatment typically includes aminoglycosides, fluoroquinolones, or tetracyclines, and pediatricians should consider tularemia in cases of febrile lymphadenopathy to avoid unnecessary costs from misguided antibiotic treatments and extended hospital stays.
Objectives: Catheter removal is recommended in adults with Staphylococcus aureus central-line-associated bloodstream infection (CLABSI) but is controversial in children with long-term central venous catheters (LTCVC). We evaluated the occurrence of catheter salvage strategy (CSS) in children with S. aureus LTCVC-associated CLABSI and assessed determinants of CSS failure.
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- A study evaluated the effectiveness of the BioFire Pneumonia plus Panel, a rapid-multiplex PCR assay, in diagnosing lower-respiratory-tract infections in critically ill pediatric patients compared to traditional culturing methods.
- It included 36 patients with varying types of pneumonia and found that the PCR assay had high sensitivity (92%) and specificity (95%), with a notable agreement between the two methods (κ = 0.74).
- The PCR assay also provided faster results (about 3.9 hours) than the reference method (about 60.5 hours), potentially leading to better-targeted antibiotic treatments and reduced unnecessary antibiotic use.
Article Synopsis
- The study aimed to analyze how socioeconomic deprivation affects the occurrence and severity of tuberculosis (TB) in children under 18 admitted to a hospital from 2007 to 2020.
- Out of 222 patients, half were considered severely affected by TB, with those in the most deprived groups having a TB incidence significantly higher (58 times) than those in the least deprived.
- While deprivation correlated with longer hospital stays, it did not significantly influence the severity of the disease after adjusting for other factors like age.
Objectives: During the COVID-19 pandemic, antibiotic use was very common. However, bacterial co-/secondary infections with coronaviruses remain largely unknown in standard wards. We aimed to investigate the characteristics of pulmonary bacterial infections associated with COVID-19 in hospitalized patients.
View Article and Find Full Text PDFBackground: The efficacy of lockdown in containing the COVID-19 pandemic has been reported in different studies. However, the impact on sociodemographic characteristics of individuals infected with SARS-CoV-2 has not been evaluated. The aim of this study was to describe the changes in sociodemographic characteristics of patients hospitalized for COVID-19 and to compare the transmission risk factors of COVID-19 before and during lockdown in France.
View Article and Find Full Text PDFBackground: The use of efficient, reliable and sensitive PCR assays is a cornerstone in the race to contain the SARS-CoV-2 pandemic. In this work we performed an independent evaluation of the RealStar® SARS-CoV-2 RT-PCR Kit Researh Use Only (Altona) for SARS-CoV-2 detection.
Methods: A comparative limit of detection (LoD) assessment was performed between RealStar® SARS-CoV-2 and the currently WHO recommended RT-PCR (WHO-PCR) workflow using a quantified clinical sample.
Article Synopsis
- - The original publication had a mistake where the author's first and last names were switched.
- - This error led to confusion regarding the authors' identities.
- - The correct names of the author group are provided to clarify the issue.
Article Synopsis
- Cutibacterium acnes (C. acnes), a bacteria usually linked to late postoperative infections, has been found to cause early surgical site infections (SSI) after a change in antibiotic protocols at a hospital.
- A study reviewed patient data from 2007 to 2017, comparing the incidence of early C. acnes SSI across three different antibiotic treatment protocols.
- Results showed that the incidence of C. acnes infections increased from 0% to 4.9% with the new protocol but decreased to 1.7% after reverting to a longer antibiotic treatment, suggesting that prolonged antibiotic use helps prevent these infections.
We report a retrospective monocentric descriptive study performed in CHI Creteil for 20 months to describe the management and outcome of amikacin monotherapy as an alternative to third-generation cephalosporins for empiric treatment of febrile urinary tract infection (FUTI) in children. Data were analyzed for 151 children, and 90 selected cases were classified as certain or highly probable FUTI. Escherichia coli infection was found in 89 cases.
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