New disinfectants.

The authors estimated the microbicidal effect of disinfectants produced by the firm Henkel Austria, namely Spitaderm, Incidin M spray, Incidur, Incidur spray, Sekusept pulver, Sekusept forte and Maranon H. The aim of the study was the verification of the effectivity of preparations and the proposal of their application in Czechoslovak practice. The estimation was performed in two stages: in vitro and in practice.

[The health status of stomatologists based on the Cornell Medical Index questionnaire].

The Cornell Medical Index--CMI was used in a group of 674 stomatologists from the North Moravian region to obtain information on their health status. The control group was formed by 126 health community doctors and factory medical officers from the Olomouc, Sumperk and Prerov districts. The results confirm that stomatologists, a risk group, suffer significantly more from somatic and mental problems, as compared with the control group.

[Microbiological purity of pharmaceutical preparation. Part 1: External remedies; and effects of type of cream, container, storage, temperature and application (author's transl)].

A fractional factorial experiment of the 2n type was carried out, to follow the effects of eight factors affecting simultaneously the microbiological purity of creams (Oleocremor leniens, Hydrocremor stearini) during the manufacturer-consumer chain. The effects of these factors (antibacterial substances, container (collapsible tube, pot), type of cream, storage (open, closed), number of takeouts, manner of taking-out (spatula, finger), temperature of storage, consumer (dermatological clinic, household) and interactive and interdependent. The microbiological purity of the creams is mostly impaired by the number of take-outs and the manner of taking-out.

[Microbiological purity of pharmaceutical preparation. Part 2: External remedies; the effects of antimicrobial agents in various contaminated creams (author's transl)].

To study the efficiency of antimicrobial agents in contaminated creams, a complete four-factor trial was performed with Oleocremor leniens, Oleocremor syndermani and Hydrocremor stearini. These creams were prepared with and without the addition of antimicrobial agents (parabene combination, potassium sorbate), contaminated with 5 genera of micro-organisms and bacteriologically examined immediately after preparation and after storage for 14 and 28 d, respectively. It was found that all four factors considered in this trial (type of cream, type of antimicrobial agent, genus of microorganism, time) are interdependent.