[Clinic and genetic polymorphism of Brugada syndrome in Russian patients, caused by mutation in SCN5A gene].

Brugada syndrome (BrS) is an inherited cardiac arrhythmic disorder, characterized by ST-segment elevation in right precordial leads V1-V2>2 mm, pseudo right bundle branch block (RBBB), T-wave inversion and an increased risk of cardiac sudden death (SCD) due to molymorphic VT. It is estimated to be responsible for 12% of SCD cases and about 20% of deaths in patients with structurally normal hearts in autopsy. Mutations in the SCN5A gene account 15-30% of all cases.

[Echocardiography of cardiac cysts].

Experience of ultrasound diagnosis of cardiac cysts of various origin accumulated by the authors during 30 years of practice is described. For the first time in the literature of this country and in foreign literature attention is attracted to a wide spectrum of possible cardiac cysts and there main diagnostic signs are presented. Eleven patients aged 9-55 years were examined.