[Results of remote gamma-therapy in acromegaly patients].

A study was made of the condition of 44 acromegalic patients at various time after gamma-beam therapy. It has shown that therapeutic efficacy depends on initial sizes of adenomas and the level of growth hormone as well as on the time of observation. At late terms after therapy normalization of the level of growth hormone was observed in 41% of patients, clinical improvement in 44%, the absence of and effect in 15%.

[Problems and perspectives of radiotherapy of non-tumor diseases].

The experience of the world leading hospitals confirms the high efficacy and appropriateness of radiation therapy of nontumorous diseases. The authors consider the general principles of the organization of radiotherapeutic service, discuss reasons that have led to a decrease in the use of this method for therapy of nontumorous diseases in this country. They also emphasize the fact that radiation therapy must have its place among therapeutic modalities used for nontumorous diseases.

[Radiotherapy of trigeminal neuralgia and post-neuritic contracture of the mimetic muscles].

The results of antiinflammatory radiation therapy were analyzed in 17 patients with trigeminal neuralgia and 7 patients with post-neuritic++ contractures of mimetic muscles. The therapy yielded positive results and was adequately tolerated by all patients. In the follow-up, no changes of the patients' general status or hematological indices were detected.

[The TDF (time-dose-fractionation) model in brachytherapy].

A method to determine TDF values by standard tables with account of RBE of low-energy x-radiation and a small area of irradiation fields was proposed. Corresponding formulas confirmed by the authors' clinical data, were developed. The authors outlined ways of using these data for assessment and design of courses of brachytherapy to minimize the risk of development of skin radiation damages.

[Skeletal scintigraphy in hemangioma of the bones].

The results of scintigraphic investigations of the skeleton of 76 bone hemangioma patients were analyzed to study the informative value of this type of investigation and to determine the efficacy of its use during establishing diagnosis and dynamic observation. The probability of detection of bone hemangiomas using scintigraphy of the skeleton with 99m Tc labeled osteotropic agents was shown to be in direct relation to the biological activity of hemangioma, its site and resolution of radiodiagnostic apparatus. The utilization of scintigraphy of the skeleton in addition to x-ray investigation permits clarification of the nature of lesion (benign or malignant), the biological activity of hemangiomas, control of the time course of a pathological process and efficacy of therapy of biologically active hemangiomas.

[Short-range x-ray therapy of cancer of the lower lip in its early stages].

The paper is concerned with the analysis of the results of brachytherapy of 169 patients with early stages of lower lip vermilion border cancer T1N0M0 in 81 patients, T2N0M0 in 85 and T3N1M0 in 3). Dosimetric planning was performed. The RUM-21 apparatus being at 60-100 kV, a single focal dose was 3.

[Late results and consequences of radiotherapy of fibrous dysplasia of the skull].

The paper is concerned with the results of follow-up of 21 patients who were given radiation therapy (gamma-beam and x-ray therapy) for fibrous osteodysplasia of the cranial bones over the period of 1946-1973. The summary focal doses varied from 30 to 100 Gy. Radiation injuries came to the foreground (changes in the skin, radiation cataract, necrosis of the maxillary bones and the development of malignant tumors in two cases).

[Radiotherapy tactics in vertebral hemangiomas].

Basing on the follow-up of 124 patients with vertebral hemangiomas over the period of 1964-1982, a differentiated approach to the choice of a therapeutic program was developed which was determined by clinical manifestations of the disease. Clinicoroentgenological findings taken as a whole were regarded as a decisive factor in determining indications to radiotherapy. The differentiated approach made if possible to use essentially different doses to achieve a therapeutic effect, and part of the patients were kept under observation.

[Potentials for using radiation treatment in complicated diabetic osteoarthropathy].

The possibility of gamma-beam therapy of aggravated diabetic osteoarthropathy is discussed. Seventy patients were exposed to local radiation (orthovolt X-ray therapy, generation voltage being 200 kV) for suppurative inflammation of the foot soft and bony tissues. The total focal dose was 300 to 500 Gy.

[Radiotherapy of ulcerated hemangioma].

A method of close-focus x-ray therapy for extensive ulcerated hemangiomas was worked out and used in combination with ointment treatment with a good clinical effect in 230 patients. The summary focal dose was 0.5-1.

[Use of dibunol in treating radiation injuries to the skin and mucosa].

The authors present the results of the use of dibunol in the form of liniment (1-10%) for the treatment of radiation cystitis and rectitis resulting from radiation therapy of small pelvic tumors, epidermitis and epithelitis that develop in the course of treatment of skin and lower lip tumors. A high efficacy of the drug in the therapy of radiation injury has been shown in 212 patients.