Publications by authors named "Pobbisetty Radhakrishnagupta Rekha"
Thyroglobulin Levels in Patients who have Undergone Hemithyroidectomy for Differentiated Thyroid Cancer. An Assessment of Levels and Trends at a Tertiary Referral Centre.
South Asian J Cancer
January 2022
Article Synopsis
- Subramanian Kannan’s study focuses on monitoring serum thyroglobulin (Tg) and thyroglobulin antibody (TgAb) levels in patients with differentiated thyroid cancer (DTC) who underwent thyroid lobectomy or hemithyroidectomy in India, highlighting a gap in existing data.
- Of the 247 DTC patients reviewed from 2015 to 2020, 17 had lower tumor sizes and varied post-surgery Tg levels, with a median follow-up time of 15 months.
- The results showed mixed trends in Tg levels post-surgery; while most patients had Tg levels below 30 ng/mL, only 23% met the criteria for an "excellent response," suggesting challenges
Ultrasound-guided fine needle aspiration cytology (FNAC) is the preferred method of identifying malignancy in palpable thyroid nodules using the Bethesda reporting system. However, in around 30-40% of FNACs (Bethesda categories III, IV, and V), the results are indeterminate and surgery is required to confirm malignancy. Out of those who undergo surgery, only 10-40% of patients in these categories are found to have malignancies, thus proving surgery to be unnecessary for some patients or to be incomplete in others.
View Article and Find Full Text PDFContext: Fine-needle aspiration cytology is the first step in evaluation of thyroid nodules. Although the Bethesda classification for reporting thyroid cytology has been purported that this uniformity in reporting cytology thereby facilitating clinical decision-making, there are also studies indicating that the reporting percentage and the rates of malignancy in each category vary considerably from center to center making the clinical decision more difficult.
Aim And Materials And Methods: We looked at our retrospective cytology and histopathology data of thyroid nodules operated between 2012 and 2014 and then prospectively collected data during 2015-2016.