Synopsis of recent research by authors named "Po-Shun Lee"
- Po-Shun Lee's research primarily focuses on the development of novel therapies for cystic fibrosis (CF), specifically exploring the role of CFTR (cystic fibrosis transmembrane conductance regulator) modulators, with significant emphasis on amplifiers that enhance CFTR biosynthesis and function.
- The use of high-throughput screening has led to the discovery of a novel class of small molecules called amplifiers that demonstrate functional synergy with existing CF treatments, potentially providing therapeutic avenues for patients lacking effective options.
- Additional studies address the impact of biological factors, such as gelsolin, on complications in hemodialysis patients and inflammatory conditions, linking these investigations to broader implications on protein-energy wasting and vascular health in chronic illnesses.
