Re-evaluating Surgical Treatment Protocol for Unstable Proximal Humerus Fractures: Emphasizing Soft Tissue Preservation via Minimally Invasive Approach over Structural Allograft Augmentation in Deltopectoral Approach: a Single-center Retrospective Study.

Background: Managing unstable proximal humerus fractures (PHFs), particularly in elderly patients, is challenging due to the need to balance stability with minimizing surgical trauma. The conventional deltopectoral approach with structural allograft for medial support is widely used but can involve significant soft tissue disruption. This study compares clinical and radiographic outcomes between a minimally invasive deltoid-split (MIS-DS) approach without allograft and the traditional deltopectoral approach with allograft.

Does the utilization of fluoroscopy affect the accuracy of prosthesis position in patients undergoing hip replacement surgery via the direct anterior approach compared to the posterolateral approach for an experienced surgeon? A single-center retrospective study.

Background: The direct anterior approach (DAA) for total hip arthroplasty (THA) has gained popularity due to perceived advantages in achieving better early outcomes. However, the theoretical benefits such as precise implant positioning and accurate leg length restoration are still inconsistent. In this study, we compared implant position and leg length discrepancy (LLD) of the DAA and posterolateral approach (PLA) conducted by a single surgeon who had mastered both approaches.

Mechanical Properties of Titanium/Nano-Fluorapatite Parts Produced by Laser Powder Bed Fusion.

Laser powder bed fusion (L-PBF) has attracted great interest in recent years due to its ability to produce intricate parts beyond the capabilities of traditional manufacturing processes. L-PBF processed biomedical implants are usually made of commercial pure titanium (CP-Ti) or its alloys. However, both alloys are naturally bio-inert, and thus reduce the formation of apatite as implants are put into the human body.

Comparison of Incidence of Adjacent Segment Pathology between Anterior Lumbar Interbody Fusion and Transforaminal Lumbar Interbody Fusion Treatments for Lumbosacral Junction.

This research compared the incidence of adjacent segment pathology (ASP) between anterior interbody lumbar fusion (ALIF) treatment and transforaminal lumbar interbody fusion (TLIF) treatment. Seventy patients were included in this retrospective study: 30 patients received ALIF treatment, and 40 patients received TLIF treatment at a single medical center between 2011 and 2020 with a follow-up of at least 12 months. The outcomes were radiographic adjacent segment pathology (RASP) and clinical adjacent segment pathology (CASP).

Atomic-scale visualization of topological spin textures in the chiral magnet MnGe.

Topological spin textures in chiral magnets such as manganese germanide (MnGe) are of fundamental interest and may enable magnetic storage and computing technologies. Our spin-polarized scanning tunneling microscopy images of MnGe thin films reveal a variety of textures that are correlated to the atomic-scale structure. Our images indicate helical stripe domains, in contrast to bulk, and associated helimagnetic domain walls.

Stimulated Nucleation of Skyrmions in a Centrosymmetric Magnet.

Understanding the dynamics of skyrmion nucleation and manipulation is important for applications in spintronic devices. In this contribution, the spin textures at magnetic domain-boundaries stimulated by application of in-plane magnetic fields in a centrosymmetric kagome ferromagnet, FeSn, with thickness gradient are investigated using Lorentz transmission electron microscopy. Switching of the in-plane magnetic field is shown to induce a reversible transformation from magnetic stripes to skyrmions, or , at the interface between differently oriented domains.

Association of osteoporosis and varus inclination of the tibial plateau in postmenopausal women with advanced osteoarthritis of the knee.

Background: Although varus inclination of the tibial plateau has increasingly been recognized as a major risk factor in the progression of Osteoarthritis of the knee (OA knee), little attention has been placed on the development of the varus inclination of the tibial plateau. Osteoporosis is a disease characterized by low bone mass and may increase the risk of a stress fracture in the proximal tibia. To date, risk factors for varus inclination of the tibial plateau are rarely reported.

Suboptimal trophectoderm mitochondrial DNA level is associated with delayed blastocyst development.

Purpose: To provide a comprehensive analysis of mtDNA quantity in D5 and D6 blastocysts, as well as a further insight to the origin of delayed blastocyst development.

Methods: A retrospective cohort analysis of 829 D5 and 472 D6 blastocysts from 460 patients who underwent in vitro fertilization (IVF) with next-generation sequencing (NGS)-based preimplantation genetic testing for aneuploidy (PGT-A). The quantity of trophectoderm mtDNA was extrapolated from the NGS data, followed by the analysis of mean mtDNA levels between D5 and D6 blastocysts of the same ploidy (aneuploid/euploid) and transfer outcomes (positive/negative clinical pregnancy).

Spin-Hall Topological Hall Effect in Highly Tunable Pt/Ferrimagnetic-Insulator Bilayers.

Electrical detection of topological magnetic textures such as skyrmions is currently limited to conducting materials. Although magnetic insulators offer key advantages for skyrmion technologies with high speed and low loss, they have not yet been explored electrically. Here, we report a prominent topological Hall effect in Pt/TmFeO bilayers, where the pristine TmFeO epitaxial films down to 1.

Mutation in fucose synthesis gene of Klebsiella pneumoniae affects capsule composition and virulence in mice.

The emerging pathogenicity of Klebsiella pneumoniae (KP) is evident by the increasing number of clinical cases of liver abscess (LA) due to KP infection. A unique property of KP is its thick mucoid capsule. The bacterial capsule has been found to contain fucose in KP strains causing LA but not in those causing urinary tract infections.