Synopsis of recent research by authors named "Po Yi Lam"
- Po Yi Lam's research focuses on the development of advanced organ-on-a-chip models to simulate human pregnancy conditions, particularly examining the interactions at the fetal-maternal interface and the impact of environmental factors such as fluid dynamics and endocrine disruptors on fetal membranes and placental functions.
- Recent findings reveal that subtle oscillations in amniotic fluid affect amnion epithelial cell health, potentially leading to pathologic changes that could compromise fetal membrane functionality, highlighting the importance of dynamic fluid conditions in fetal development.
- Lam's work also investigates the effects of oxidative stress and endocrine-disrupting compounds using innovative microfluidic models, providing vital insights for drug testing and understanding pregnancy-related complications such as preterm birth and placental dysfunction.
