Publications by authors named "Po C Chang"
Article Synopsis
- The study aimed to identify specific microRNAs (miRNAs) that may predict repeated implantation failure (RIF) in patients undergoing in vitro fertilization (IVF).
- Researchers analyzed miRNA profiles from the endometrial tissue of 25 patients in a discovery cohort and validated findings in 11 additional patients.
- They identified three key miRNAs (hsa-miR-20b-5p, hsa-miR-155-5p, hsa-miR-718) that predicted RIF with over 90% accuracy, suggesting these could serve as useful diagnostic biomarkers to improve IVF success rates.*
In this study, we report the dependence of the nanoparticle dispersion on the zero-conversion initiator efficiency in the nanocomposites formed by poly(N-vinyl carbazole) (PNVK) and acrylic acid-modified iron oxide (AA-FeO) nanoparticles via free radical solution polymerization of the precursor solution, that is, a thorough mixture of 28.5 wt% AA-FeO nanoparticles and the N-vinyl carbazole (NVK) monomer with the solvent dimethylformamide and azobisisobutyronitrile as an initiator. Here three different types of the dispersion state of AA-FeO nanoparticles in the PNVK matrix have been distinguished by a combined approach of transmission electron microscopy and small-angle X-ray scattering coupled with real-space models of the nanoparticle assemblies.
View Article and Find Full Text PDFBackground: Na channel blockers are effective in suppressing delayed afterdepolarizations (DADs) in isolated Purkinje fibers. However, in isolated mouse ventricular myocytes lacking calsequestrin, only those Na channel blockers that also inhibit type 2 ryanodine receptor channels were effective against spontaneous Ca elevation (SCaE) and DADs.
Objective: To test the hypothesis that combined Na channel and type 2 ryanodine receptor channel blocker ((R)-propafenone) is more effective than a Na channel blocker (lidocaine) in suppressing SCaE and DADs in the intact rabbit ventricles.