Publications by authors named "Po An Chen"

Interactions between metal cations, notably Cu(II), and humic substances (HS) affect their mobility, bioavailability, and toxicity. This necessitates a molecular-level determination of the nature of HS functional groups binding Cu(II) (Cu-HS) and effects of pH on them. This study investigates the pH effects on the spectroscopic and structural properties of the complexes of Cu(II) with HS and representative model compounds using differential absorbance spectroscopy (DAS), examination of the properties of the d-d transition band characteristic for Cu(II) ions, and quantum chemical (QC) calculations.

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Purpose: To investigate efficacy of 3-month teriparatide(TPD) and compare this treatment with vertebroplasty in terms of clinical and radiographic outcomes after osteoporotic vertebral compression fractures (OVCFs).

Methods: This is a retrospective matched cohort study. Patients who received conservative treatment with at least 3-month TPD treatment for acute OVCF with at least 6 months follow-up were included.

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The lncRNA tumor protein translationally controlled 1-antisense RNA 1 (TPT1-AS1) is known for its oncogenic role in various cancers, but its impact on the pathological progression of prostate cancer remains unclear. Our previous study demonstrated that the RE1-silencing transcription factor (REST) regulates neuroendocrine differentiation (NED) in prostate cancer (PCA) by derepressing specific long non-coding RNAs (lncRNAs), including TPT1-AS1. In this study, we revealed that TPT1-AS1 is overexpressed in LNCaP and C4-2B cells after IL-6 and enzalutamide treatment.

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Purpose: Linked component of total elbow arthroplasty (TEA) consisted of bushing and locking pins. Failure of linked components is a rare complication of TEA. This study aims to investigate the mechanism and consequence of failure of the linkage mechanism in TEA surgeries.

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Article Synopsis
  • The study developed a new algorithm for classifying thumb polydactyly based on physical characteristics rather than just radiographic levels of duplication.
  • It categorized conditions into hypoplastic, symmetric (adequate/inadequate), and asymmetric (ulnar/radial dominant) types using four key traits: floating, symmetry, dominant side, and joint characteristics.
  • A retrospective analysis of 500 patients showed that the new classification effectively predicted treatment options, helping pediatricians and parents navigate surgical decisions despite not detailing surgical techniques.
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Ketamine has been abused as a psychedelic agent and causes diverse neurobehavioral changes. Adolescence is a critical developmental stage but vulnerable to substances and environmental stimuli. Growing evidence shows that ketamine affects glutamatergic neurotransmission, which is important for memory storage, addiction, and psychosis.

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Objective: Double-low CT aortography (DLCTA) is increasingly used in follow-up studies of aortic aneurysm after endovascular aneurysm repair (EVAR). However, whether DLCTA can reliably detect the presence of endoleak is not clear.

Methods: From February 2014 to October 2019, patients who received EVAR, underwent CT surveillance, and had at least one standard CTA protocol (120 kVp, 400 mg I/kg) and one DLCTA (70-80 kVp, 200 mg I/kg) were included.

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Capacitive deionization (CDI), a m ethod with notable advantages of relatively low energy consumption and environmental friendliness, has been widely used in desalination of saltwater. However, due to the weak electrical double-layer electrosorption of ions from water, CDI has suffered from low throughput capacity that may limit its commercial applications. Thus, it is of importance to develop a high-efficiency and engineering-feasible CDI process.

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  • Scientists studied arsenic compounds from landfill gas processing to understand their chemistry better.
  • They found that the structure of these compounds is similar to other arsenic materials that contain sulfur.
  • The results can help in creating methods to treat and manage arsenic in landfill gas more effectively.
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  • * It can cause typical side effects like fever and headache, but there have been rare cases of neuropsychiatric issues reported.
  • * In Taiwan, over 15.2 million doses were given by the end of 2022, and this report discusses a unique case of Ekbom's syndrome and mania occurring in a patient after receiving the vaccine at three-month intervals.
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Background: The Wassel classification is commonly used for cases of radial polydactyly but has not been used to predict surgical outcomes. This study aimed to investigate the predictive factors of surgical outcomes using the Wassel type and symmetry of duplication.

Methods: Forty-five patients with 47 radial polydactylies were reviewed using the Japanese Society for Surgery of the Hand (JSSH) scores 4.

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  • When a disease spreads, it's crucial to vaccinate people quickly and effectively, especially when there's a limited budget.
  • The paper discusses ways to design a plan to vaccinate people so that those who get vaccinated also help protect their neighbors from getting sick.
  • Several algorithms are tested to find the best way to do this efficiently, with some showing good results in experiments for how well they work.
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(IPr)GaCl/AgSbF, AgSbF, and GaCl catalyzed substitution of the hydroxyl of secondary and tertiary propargylic alcohols with organoboronic acids via C-C bond formation, and GaCl effectively synthesized all-carbon quaternary propargylic centers. These catalysts performed the substitution at carbons bearing alkyl substituents, which has been problematic for other systems. Highly hindered carbon stereocenters were thus produced, including quaternary centers bearing doubly ortho-substituted aryl rings, that are difficult to access with traditional methods.

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Objective: The glutamate system plays a major role in the development of neuropsychiatric disorders such as addiction, epilepsy, dementia, and psychosis. MK-801 (dizocilpine), an uncompetitive -methyl-D-aspartate (NMDA) receptor antagonist, could increase locomotor activity and stereotyped neurobehaviors mimicking schizophrenic-like features in the mouse model. The study would explore the neuropharmacological differences of risperidone and valproic acid on the MK-801-induced neurobehavioral changes.

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  • Bao-chung tea gets its special smell from a process where it is oxidized and then heated in a pan.
  • Experts used different heating times and stirring methods to see how they changed the tea’s smell and ingredients.
  • They discovered that the timing of heating is really important, and they can guess what the tea will smell like based on its smell before heating.
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The operational duration of shaking tea leaves is a critical factor in the manufacture of oolong tea; this duration influences the formation of its flavor and fragrance. The current method to control the duration of fermentation relies on the olfactory sense of tea masters; they monitor the entire process through their olfactory sense, and their experience decides the duration of shaking and setting. Because of this human factor and olfactory fatigue, it is difficult to define an optimum duration of shaking and setting; an inappropriate duration of shaking and setting deteriorates the quality of the tea.

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  • - The study explores a catalytic pathway for turning water into oxygen using dinuclear transition metal complexes, particularly with two Ru centers at different separations.
  • - Two new symmetrical bis-tridentate polypyridine ligands were designed, resulting in one catalyst with closely spaced Ru centers being more effective in water oxidation when reacting with Ce at pH 1.
  • - The research highlights a bridging ligand that breaks down under Ce's influence to create catalyst fragments, while also noting a second less reactive catalyst due to its structural stability and warnings about using Ce due to possible catalyst decay.
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Non-volatile resistive switching, also known as memristor effect, where an electric field switches the resistance states of a two-terminal device, has emerged as an important concept in the development of high-density information storage, computing and reconfigurable systems. The past decade has witnessed substantial advances in non-volatile resistive switching materials such as metal oxides and solid electrolytes. It was long believed that leakage currents would prevent the observation of this phenomenon for nanometre-thin insulating layers.

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Some lichens provide the resources of common traditional medicines and show anticancer effects. However, the anticancer effect of () is rarely investigated, especially for oral cancer cells. The aim of this study was to investigate the cell killing function of methanol extracts of (MEUB) against oral cancer cells.

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Purpose: To assess the image quality of 80-kVp craniocervical CT angiography (CCCTA) protocol combined with adaptive statistical iterative reconstruction-V (ASIR-V) and low-dose contrast medium (CM).

Methods: A total of 119 patients were randomly divided into three groups. For group A, 120-kVp protocol was followed with 60 ml CM and filtered back projection; for group B, 80-kVp protocol with 60 ml CM and ASIR-V; and for group C, 80-kVp protocol with 45 ml CM and ASIR-V.

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