[Enterovirus infection as a risk factor of acute coronary syndrome and its complications].

Antigens of enteroviruses were detected quantitatively in the modified complement-binding reaction in blood samples from 102 of the 208 (49%) patients with ACS, in coronary artery tissues from 23 of 24 and heart from 51 of 94 (54.3%) patients with MI who died from cardiogenic shock and/or cardiac rupture. The relative level of enterovirus antigen (RLEVA) in the blood of patients with MI complicated and uncomplicated by cardiogenic shock and/or cardiac rupture was 0.

One intrauterine device lost, two found.

During a search for a recently inserted, lost intrauterine device (IUD), a pelvic x-ray found two devices. One of the IUDs had been inserted 9 years earlier and was thought expelled.

Outbreak of enterotoxigenic Escherichia coli infection with an unusually long duration of illness.

Background: Enterotoxigenic Escherichia coli (ETEC) is an emerging cause of foodborne outbreaks of infection in the United States, yet its epidemiology is not completely understood.

Methods: In September 2004, we investigated an outbreak of infection due to ETEC at an Illinois corporation following a meal served to approximately 700 employees. Clinical samples were negative for enteric pathogens and were tested for ETEC using stool culture and polymerase chain reaction (PCR).

[Blood plasma level of endothelin in miners of a deep coal mine].

In 60 miners working in a deep coal mine the blood plasma level of endoteline-1 (E-1) was measured by the immunoenzyme technique immediately after working shift. Those in the mining where the working conditions are especially harsh were found to have the highest level of E-1 exceeding the control values. In studying the age-related content of E-1 in blood plasma of coal miners the highest levels of E-1 were recordable in workers 20 to 30 years old, declining and differing in age groups 20-30 and 41-50 years old.

[Changes in the interleukin-6 and interleukin-10 concentrations in the blood plasma of miners working in deep coal mines].

Blood plasma levels of interleukin-6 (IL-6) and interleukin-10 (IL-10) were measured in 45 miners working in a deep coal mine immediately after work shift using an immunoenzyme technique. The highest IL-6 level was recorded in those miners engaged in hard work under most adverse conditions of underground workings--it was found to exceed the control values. The same group of workers demonstrated the lowest level of IL-10 that differed from the control value.

Significance of success rate of external cephalic versions and vaginal breech deliveries in counseling women with breech presentation at term.

Objective: To appreciate the role of success rates of external cephalic versions and breech deliveries, in order to assess the risk reduction in women with breech presentation at term.

Study Design: We reviewed the patient files of all women with breech presentation whom had an attempt of external cephalic version (ECV) at term. Most of the ECVs were performed under intravenous ritodrine infusion.

Indomethacin for preterm labor: a randomized comparison of vaginal and rectal-oral routes.

Objective: To compare the efficacy of intravaginal and intrarectal plus oral indomethacin for the treatment of preterm labor.

Methods: Between December 1996 and November 1998, 46 eligible gravidas admitted with singleton pregnancies and idiopathic preterm labor before 33 gestational weeks were randomized to receive 200 mg of intravaginal or intrarectal plus oral indomethacin.

Results: Twenty-three subjects were allocated to each study group.

[The effect of acute and chronic overheating on morphological changes in the liver].

Disturbances were disclosed in the functioning of the lysosomal and vacuolar apparatus in an electronic and histochemical investigation of 75 Wistar albino rats and 10 control animals exposed to acute and chronic overheating, with the numbers and structure of lysosomes undergoing changes, lysosomal membranes disrupting, which event was accompanied by an outgo of lysosomal contents into the cellular cytoplasm and beyond. There was no longer Golgi apparatus as a single whole; cellular cytoplasm stored lipid drops of low electron density with membrane inclusion and products of reaction to acid phosphatase in their matrix. Disruption of lysosomes and identification of acid phosphatase in cellular cytoplasm and Disse's space was presumably a cause of damage to the Golgi apparatus.

[Effects of age and length of service on the state of the renin-angiotensin-aldosterone system and prostaglandin synthesis in coal miners].

Radioimmune assay determined serum renin activity, serum aldosterone level and its excretion with urine, amounts of thromboxane A2 (TxA2), prostacyclins PgI2 and PgF2a in urine of 76 apparently healthy miners before and after the working shift. Conventional techniques were used for estimation of blood and urine electrolytes and creatinine. In this connection activity of renin-angiotensin-aldosterone system (RAAS) in the miners before and after the work appeared to depend on the age and the length of service, to reach the maximum at the age of 31-40 and at 11-15 years of the service.

[Correction of bronchial hyperreactivity with Corinfar in patients with chronic renal insufficiency].

As shown in the provocative tests in eighteen 24-42 year old chronics with renal insufficiency, corinfar pretreatment (20 mg sublingually) can protect against acetylcholine-induced bronchial hyperreactivity. This ability of the drug can be useful to reduce hyperreactivity of the bronchi of patients with chronic renal insufficiency.

[The role of pharmacological tests in detecting disorders in the bronchial patency and bronchial reactivity of patients with chronic glomerulonephritis].

Data are reported of a study of the effect of atrovent, salbutamol and acetylcholine on bronchial patency and reactivity of the bronchi in 89 patients with glomerulonephritis (age: 17-49 years) with normal renal function and at the stage of chronic renal failure. The tests proved highly informative. Latent bronchospasm was found in 12.

[Diseases of the kidneys and urinary tract and possibilities of their active detection in miners].

The examination of 630 miners aged 18-64 working in the mines of the Lugansk region revealed urinary and renal diseases in 15.7% of them. They were affected with chronic prostatitis (34.

[Effect of a single overheating on kidney ultrastructure].

Large human populations have to live and work under conditions of heat in the arid zones or in industry. It is shown in the experiment, that a single overheating of animals of various duration results in a considerable damage of glomeruli and tubules the clinical manifestation of which is the development of acute renal failure.

[The determination of aldosterone, thromboxane A2 and prostacyclin in biological fluids].

The authors' findings have lead them to a conclusion that urinary prostacyclin may be measured directly without preliminary extraction. Double freezing-defrosting of the samples did not change urinary thromboxane A2 level. Prolonged (up to 8 months) storage did not tell on urinary thromboxane A2 and blood plasma aldosterone levels.

[Clinico-morphologic comparisons in mesangiocapillary glomerulonephritis].

Clinical, morphological and immunological examination was carried out in 146 patients with mesangiocapillary glomerulonephritis. The differences in the clinical manifestations of the disease were not significant. The lobular variant was more frequently distinguished by microhematuria, increased level of creatine and reduction of the blood serum complement.

[One of the possible mechanisms of development and progression of chronic glomerulonephritis].

Proceeding from clinical examination of 430 patients with chronic glomerulonephritis (GN) and morphological, histochemical and biochemical studies on kidney biopsy specimens the author has proposed and substantiated a hypothesis, according to which prolonged raised protein reabsorption in cells of the proximal tubules (PT) of the kidney can cause breakage and distortion of the activity of transport systems responsible for the absorption and catabolism of macromolecules. These changes can result in PT cell breakage, escape of lysosomal enzymes into the lumen and basal membrane of PT cells and pericanalicular interstice with further development of cortical interstitial sclerosis. The combination of the above mentioned disturbances would lead to GN progression and development of renal insufficiency.

[Work experience of the Minsk City Epidemiological Health Station in organizing a system for the epidemiological health surveillance of infectious diseases].

The system of the sanitary and epidemiological surveillance of infectious diseases comprises three aspects: supply of information, epidemiological and sanitary-hygienic surveillance. The system ensures the reliable epidemiological diagnosis, close collaboration in the work of specialists of sanitary and epidemiological departments, the differentiated surveillance of epidemiologically important objects, and the effectiveness of measures aimed at decreasing the infectious diseases incidence rates.

[Nephrotic syndrome in primary glomerulonephritis].

The authors provide the clinico-morphological data obtained in 189 patients with primary glomerulonephritis (GN). The disease was manifested clinically by the nephrotic syndrome (NS). The NS was most commonly induced by membranous-proliferative GN (MPGN), membranous GN (MGN), diffuse mesangio-proliferative GN and focal segmental glomerulosclerosis (FSGS), accounting for 31, 25, 22.