Gene Polymorphisms (, , , ) in Total Hip Arthroplasty Outcome Patients.

A total hip arthroplasty (THA) can improve quality of life, but loosening of the hip prosthesis is a complex problem in which vitamin D may also play a role. The Vitamin D Receptor (VDR) is involved in the response of cells to the action of vitamin D, and its genetic variability raises the question of whether individual differences could influence the risk of prosthesis loosening. The aim of this study was to investigate the relationship between single nucleotide polymorphisms (SNPs) (, , and ) and the serum VDR and 25(OH)D levels in three groups of patients: (1) arthroscopy patients after THA without loosening of the prosthesis (CA-Control Arthroplasty), (2) patients after THA with loosened hip prostheses (L-Loosening) and (3) the control group (C-Control).

Congenital Muscular Torticollis-Current Understanding and Perinatal Risk Factors: A Retrospective Analysis.

Introduction: Congenital muscular torticollis (CMT) is an asymmetrical head position resulting from structural changes in the sternocleidomastoid (SCM) muscle that occurs early during a child's development or due to perinatal trauma. Children with CMT exhibit a marked imbalance in tension between the SCMs. In a typical clinical picture, an ultrasound scan is performed to reveal characteristic lesions, such as tissue fibrosis or post-traumatic changes.

Vitamin D Metabolic Pathway Components in Orthopedic Patientes-Systematic Review.

Vitamin D takes part in the functioning of many processes that ensure the homeostasis of the body. In orthopedics, it is indicated as an inseparable element ensuring proper bone growth and functioning, and its deficiencies are indicated in various diseases, mainly in the proper structure and function of the skeleton. In this review, we focus on the most important components of the vitamin D metabolic pathway, in correlation with selected orthopedic conditions.

rs7041 and rs4588 Polymorphisms in Vitamin D Binding Protein Gene (VDBP) and the Risk of Diseases.

The purpose of the study was to investigate the role of vitamin D binding protein (VDBP, DBP) and its polymorphism in the vitamin D pathway and human health. This narrative review shows the latest literature on the most popular diseases that have previously been linked to VDBP. Vitamin D plays a crucial role in human metabolism, controlling phosphorus and calcium homeostasis.

TPH1 gene polymorphism rs211105 is associated with serotonin and tryptophan hydroxylase 1 concentrations in acute pancreatitis patients.

Background: The role of serotonin and its metabolic pathway in proper functioning of the pancreas has not been thoroughly investigated yet in acute pancreatitis (AP) patients. Tryptophan hydroxylase (TPH) as the rate-limiting enzyme of serotonin synthesis has been considered for possible associations in various diseases. Single-nucleotide polymorphisms (SNPs) in TPH genes have been already described in associations with psychiatric and digestive system disorders.

Role of rs193922155 in the etiopathogenesis of osteogenesis imperfecta with description of the phenotype: A case report.

Introduction: Osteogenesis imperfecta (OI) is a disorder of the connective tissue that mainly causes the bones to become excessively brittle. The vast majority of OI cases are associated with mutations in the genes encoding the I alpha.

Patient Concerns: A 57-year-old woman office worker was admitted because of severe, long-lasting pain in the thoracic spine while bending down.

Vitamin D Binding Protein (VDBP) and Its Gene Polymorphisms-The Risk of Malignant Tumors and Other Diseases.

Vitamin D is an important component of the endocrine system that controls calcium homeostasis and bone mineralization. Because of the very short half-life of free serum vitamin D it is stabilized and transported to target tissues by being bound to the vitamin D binding protein (VDBP). The most common polymorphisms: rs4588 and rs7041 in the vitamin D binding protein gene may correlate with differences in vitamin D status in the serum.

Gene Polymorphism rs10877012 in Patients Diagnosed with Colorectal Cancer.

Colorectal cancer (CRC) is the third most commonly occurring cancer worldwide. Intestinal cells are gene expression sites and, as a consequence, they are capable of converting pro-vitamin D into the active paracrine and autocrine forms. It was demonstrated that rs10877012 polymorphism in the gene influenced the circulating vitamin D level.

Unusual Location of Osteoid Osteoma in the Acromion.

We present the clinical case of a 14-year-old female patient complaining of omalgia. A focus of osteoid osteoma located in the acromion was diagnosed. The lesion was removed using the arthroscopic technique, and the symptoms subsided completely.

Periprosthetic Metastatic Lesion in Stem Region after THA. Case Study.

The paper describes a periprosthetic metastatic lesion in the stem region which developed 4 years after cementless total hip arthroplasty in a 64-year-old female patient. The patient underwent primary THA due to osteoarthritis in 2010. In June 2014, she presented with increasing hip pain.

The Effect of Isometric Massage on Global Grip Strength after Conservative Treatment of Distal Radial Fractures. Pilot Study.

Background: The most common fracture of the distal end of the radius is Colles' fracture. Treatment modalities available for use in hand rehabilitation after injury include massage. The aim of this study was to evaluate the effect of isometric massage on the recovery of hand function in patients with Colles fractures.

[Long-term outcomes after "anatomic" reconstruction of anterior cruciate ligament using central third of patellar tendon].

Unlabelled: Reconstruction of the anterior cruciate ligament (ACL) is one of the most commonly performed procedures in orthopedics.

Aim: The aim of the study was to evaluate long-term results of anterior cruciate ligament reconstruction using middle third patellar tendon grafts.

Materials And Methods: The study included 29 patients with an average 8 years follow - up.

[Current concepts in surgical treatment of chronic ankle joint instability].

Ankle sprain is one of the most common musculoskeletal injuries. Initial treatment of choice in acute injury is conservative and is obtained by immobilization. The goal of such treatment is to heal ruptured capsular-ligamentous complex.

[Thermal shrinkage of anterior cruciate ligament--if it works?].

Unlabelled: Common used method of treatment of anterior cruciate ligament deficiency is reconstructive surgery. But in cases of incomplete tear of ligament or graft failure one of the treatment options is thermal shrinkage of remain tissue. Although this method is widespread among clinicians, still there are a lot of controversies.

[Dislocation after total hip arthroplasty--the problem is still present, reasons and treatments].

Dislocation after total hip replacement remains a significant problem in orthopedic practice. Despite the use of more modem implants risk of instability is estimated at a few percent for primary treatment and for several procedures. The standard procedure in case of the first dislocation is reduction of the prosthesis in general anesthesia.

Results of two-stage operative treatment of anteromedial instability of the knee.

Background: Proper treatment of massive knee injuries still constitutes a challenge for clinicians. Most often a torsion knee injury results in a rupture of the medial collateral ligament and anterior cruciate ligament. There is still no consensus on whether total rupture (Grade III) of the medial collateral ligament requires surgery, but it is well known that anterior cruciate ligament injury will require reconstructive surgery.

Venous thromboembolism prophylaxis in arthroscopic surgery.

The prophylaxis and epidemiology of venous thromboembolism (VTE) following major orthopaedic procedures has been widely discussed in the world literature. Significantly less attention in the recent years has been paid to antithrombotic prophylaxis following arthroscopic procedures. In the past few years numerous controversies have developed as a result of contradictory guidelines advocated by various centres.

[Instability and other local complications after revision hip replacement in one patient--a case report].

Arthroplasty of the hip is now considered as a safe procedure. The most frequent complications include such terms as pulmonary embolism, myocardial infarction and thrombosis locally at the lower extremities, wound infection, loosening of the implant, periprosthetic fracture, dislocation of the prosthesis or sciatic nerve injury. The work is described for patient operated at the Department of Orthopaedics WIM, in which within 3 years from revision surgery made of loosening of the implants there were multiple complications, including multiple prosthetic dislocations, periprosthetic fracture, nonunion and damage of the stabilizing plate.

Dynamic testing of bone grafts.

The influence of cycling loading force on the substrate made of frozen bone grafts was investigated. Three layers of bone grafts were compacted in a spherical model of hip joint acetabulum and then subjected to a sinusoidal loading force. For each layer a series of N = 30 loading cycles were performed.

Testing the stability of the polyethylene acetabulum cemented on a frozen bone graft substrate on a model of an artificial hip joint.

The stability of the polyethylene acetabulum cemented on a substrate made of frozen bone grafts was investigated. The force was applied to the edge of the acetabulum and the magnitude of the force and resulting displacement were recorded. These tests were preceded by stress testing, during which the acetabulum was subjected to loading forces of 1 or 3 kN through 100,000 cycles.

Fixation of patellar tendon bone graft in reconstruction of patellar ligaments. Comparison of bioabsorbable and metal interference screws--results of treatment.

Background: The central third of the patella tendon is probably the most common ACL graft material because the bone tendon bone (BTB) construct provides robust graft incorporation and a mechanically sufficient substitute. Metal and bioabsorbable interference screws ensure good initial fixation strength of the bone plug.

Material And Methods: A total of 78 patients (mean age 29 years) were assigned to a bioabsorbable screw [L-15 Lactosorb] group (Group I of 34 patients) or a metal screw group (Group II of 44 patients).

Cemented primary total arthroplasty for acetabular protrusion in patients with rheumatoid arthritis.

Background: The degenerative changes in hip joints observed in patients RA are associated with acetabular bone deficiencies. Therefore total hip arthroplasty performed in such patients requires bone grafting to restore the deficiencies. The aim of the study was to assess the long term-term results of primary total hip arthroplasty in patients with RA including an assessment of the usefulness of auto-and allograft in restoring bone deficiencies in acetabular protrusion.

Functional evaluation of patello-femoral incongruence by computer tomography.

Background. The purpose of this study was to specify the types of incongruence detected in the patellofemoral joint by computer tomography. The joints were examined in both internal and external rotation of the lower leg.