Cohort study of workers employed in an Italian tire manufacturing plant, 1962-2004.

Purpose: To investigate mortality and bladder cancer incidence among workers of a tire manufacturing plant where antioxidants severely contaminated by beta-naphthylamine were never used.

Methods: Mortality follow-up was performed of 9,501 workers first hired between 1962 when the plant started operations and 2000. Person-years of observation from 1962 to 2004, expected deaths, and standardized mortality ratios (SMR) were calculated.

[Cardiovascular disease prevention: results from Programma FASEN - H San Raffaele].

We studied 9145 workers allocated among Italian country employed in the same factory. Most of them were male, mean age 47,6 (20,2 View Article and Find Full Text PDF

Confounders and confusion: Dealing with cancer cases of occupational origin.

Background: The recognition of occupational cancers is often hampered by confusion between the individual determinants of the disease and effects at the group level.

Methods: Here we propose an approach, based on the evaluation of the attributable risk at the group level, that provides quantitative estimates of the roles of multiple causes in individuals affected of cancer within a population exposed to occupational risk.

Results: The estimate of individual probability can be easily obtained computing the attributable risk.

[The active search for occupational cancers].

The active search for occupational neoplasms has been implemented only in Italy. This search can be carried out with two modalities: the in-hospital face-to-face interview of selected cancer cases, and the linkage of available information (OCCAM). Both were supported by a special project on occupational carcinogenesis of the Lombardy Region.

The Italian surveillance system for occupational cancers: characteristics, initial results, and future prospects.

Background: Occupational cancer monitoring is important for cancer prevention and public health protection. A surveillance system for identifying occupational cancer risks and cancer cases in Italy that are likely to be of occupational origin using information available in the Italian Social Security archives was created and assessed. Persons employed in the private sector, the employing company, its industrial sector, and years of employment are available in these archives.

[The active search for occupational cancer cases: bladder cancer in Lombardy Region].

Objective: A study called OCCAM (OCcupational CAncer Monitoring) has been carried out in order to establish a nationwide surveillance system for occupational cancer. This project consists of population-based case control studies where information on past occupations are automatically gathered National Institute for Social Security's archive, cancer cases are obtained from Cancer Registries (CR) and controls are sampled from population files of the National Health Service. As previous results obtained using CR were encouraging, we tried to use regional hospital discharge records as a source of incident cases.

[Mortality study of asbestos cement workers in Emilia-Romagna].

Objective: The present study updates to 06/30/1998 the cohort mortality study of 3358 workers employed in 10 asbestos cement production plants in the Italian region Emilia-Romagna.

Participants: The cohort includes 2712 males and 646 females.

Results: Overall mortality was significantly increased (SMR=131, IC95%:108-127).

[Mortality from malignant pleural neoplasms in Broni (Pavia), 1980-1997].

Mortality for malignant pleural neoplasms (1980-97) was studied in Broni (Pavia) and in the surrounding area in order to update previous studies indicating a high incidence of pleural mesothelioma, due to the presence of an asbestos-cement factory. Observed mortality for pleural neoplasms was compared to expected figures derived from mortality rates of the population resident in Province of Pavia. A significant increase was found in Broni (SMR 825, CI 95%: 604-1, 100, 46 observed).