[Molecular genetic diagnosis and clinical features of hereditary neuropathy with liability to pressure palsies in Belarusian patients].

Objective: To analyze the molecular defect, a phenotype of hereditary neuropathy with liability to pressure palsies (HNPP, OMIM 162500), in patients with PMP22 gene mutation caused by 1.5 Mb deletion at 17p11.2.

[The influence of otolithic afferentation on the vestibulo-ocular interaction in the patients presenting with an unilateral lesion in a peripheral vestibular neuron].

The objective of the present work was to study the influence of otolithic afferentation on the vestibulo-ocular interaction in 20 patients with vestibular neuronitis (at the stages of decompensation and subcompensation) and in 30 healthy subjects by the electronystagmographic technique. The sinusoidal (program 1) and eccentric (program 2) rotation was applied with the angular velocity of 10 degrees/s (stimulus 1, rotation rate 0.04 Hz), 30 degrees/s (stimulus II, rotation rate 0.

[Modern diagnostics of vestibular dysfunction].

Based on the data of anatomy and physiology of vestibular apparatus, authors reviewed methods of assessment of its functional state, theoretical and practical aspects of their strength and limitations. A special attention is drawn to current approaches to investigation of vestibular-ocular reflex (VOR) in different pathologies. The authors emphasized that the diagnostics of vestibular dysfunction should be based on a battery of tests.

[Gaze-evoked suppression of the vestibular-ocular reflex in patients with posterior cervical sympathetic syndrome].

This vestibulometric (sinusoidal rotation) study included patients with posterior cervical sympathetic syndrome (n=40) and with vestibular neuronitis (n=20) as well as 20 healthy subjects of the control group. Vestibular dysfunction was induced by the method proposed by de Klein. The patients with posterior cervical sympathetic syndrome in the decompensation phase displayed abnormal gaze-evoked suppression of the vestibular-ocular reflex when their head movements lined up with sinusoidal rotation.