Awake surgery with mapping-based resection to treat focal epilepsy in eloquent brain areas.

Objectives: Resective surgery is a potential therapeutic option for select patients with intractable focal epilepsy. However, the presence of ictal onset zones within or surrounding highly functional brain areas presents a surgical challenge, leading to poor seizure and functional outcomes. This report describes our experiences with awake mapping-tailored resection of epileptogenic areas involving eloquent cortices and evaluates their feasibility, tolerance, limitations, and significance.

[Prospective longitudinal study on the evolution of autobiographical memory in patients irradiated for benign skull base tumour].

Purpose: Cranial irradiation can lead to long-term neurological complications, in particular memory disorders. The aim of this prospective study is to evaluate the impact of irradiation of benign skull base tumours located near the hippocampi on autobiographical memory.

Patients And Methods: From 2016 to 2019, patients with cavernous sinus meningioma or pituitary adenoma treated with normofractionated irradiation were included.

The Poultry Red Mite, Dermanyssus gallinae, travels far but not frequently, and takes up permanent residence on farms.

Management of Dermanyssus gallinae, a cosmopolitan hematophagous mite responsible for damage in layer poultry farming, is hampered by a lack of knowledge of its spatio-temporal population dynamics. Previous studies have shown that the circulation of this pest between farms is of strictly anthropogenic origin, that a mitochondrial haplogroup has been expanding on European farms since the beginning of the 21 century and that its local population growth may be particularly rapid. To refine our understanding of how D.

The Adiponectin Receptor Agonist, ALY688: A Promising Therapeutic for Fibrosis in the Dystrophic Muscle.

Duchenne muscular dystrophy (DMD) is one of the most devastating myopathies, where severe inflammation exacerbates disease progression. Previously, we demonstrated that adiponectin (ApN), a hormone with powerful pleiotropic effects, can efficiently improve the dystrophic phenotype. However, its practical therapeutic application is limited.

Histological Methods to Assess Skeletal Muscle Degeneration and Regeneration in Duchenne Muscular Dystrophy.

Duchenne muscular dystrophy (DMD) is a progressive disease caused by the loss of function of the protein dystrophin. This protein contributes to the stabilisation of striated cells during contraction, as it anchors the cytoskeleton with components of the extracellular matrix through the dystrophin-associated protein complex (DAPC). Moreover, absence of the functional protein affects the expression and function of proteins within the DAPC, leading to molecular events responsible for myofibre damage, muscle weakening, disability and, eventually, premature death.

High-throughput behavioral phenotyping of tiny arthropods: Chemosensory traits in a mesostigmatic hematophagous mite.

Pest management using attractive and/or repellent semiochemicals is a key alternative to synthetic insecticides. Its implementation requires a good understanding of the intra- and interspecific chemical interactions of arthropod pests, their interactions with their abiotic environment, as well as their evolutionary dynamics. Although mites include many pest species and biocontrol agents of economic importance in agriculture, their chemical ecology is largely understudied compared to insects.

Communicating chronic hydrocephalus: A review.

Formerly called normal pressure hydrocephalus, communicating chronic hydrocephalus (CCH) is a condition affecting 0.1 to 0.5% of patients over 60years of age.

Sacroiliac joint pain after lumbar fusion. A study with anesthetic blocks.

Low back pain persisting or appearing after a technically successful lumbar fusion challenges clinicians. In this context, the sacroiliac joint could be a possible source of pain, but the frequency of its responsibility is not really known. We used sacroiliac anesthetic blocks, the gold standard for diagnosis, to determine this frequency.

[The life of doctor Louis-Désiré Véron (1798-1867)].

The life of doctor Louis-Désiré Véron (1798-1867) was an incredible odyssey. Starting his professional life as an 'Interne des Hôpitaux de Paris', he found himself unable to enter the medical establishment at a time it was practically impossible to succeed in Parisian society without having being born into a wealthy family. He was eventually able to take his revenge on Paris when he had made a fortune from pharmacy.

Complex regional pain syndrome after thromboendarterectomy: which type is it?

The authors describe a complex regional pain syndrome (CRPS) and discuss its type according to the presence or absence of nerve injury. A patient underwent thromboendarterectomy of the right popliteal artery. Subsequently, right lower limb reflex sympathetic dystrophy developed, which was confirmed by scintigraphy and responded well to calcitonin treatment.

QTL analysis of photosynthesis and water status traits in sunflower (Helianthus annuus L.) under greenhouse conditions.

The identification of QTL for several physiological traits in sunflower is described. Traits related to photosynthesis (leaf chlorophyll concentration, net photosynthesis and internal CO(2) concentration) and water status (stomatal conductance, transpiration, predawn leaf water potential, and relative water content) were evaluated in a population of recombinant inbred lines under greenhouse conditions. Narrow-sense heritabilities were low to average.

Infectious risk associated with wastewater reuse: an epidemiological approach applied to the case of Clermont-Ferrand, France.

Wastewater reuse raises the question of health risk and the epidemiological surveys needed. An epidemiological and environmental approach was used to check the security for the exposed populations (surrounding and agricultural population in Clermont-Ferrand. Four information systems were set up: two sentinel systems joining general physicians (15) and pharmacists (7) for the surrounding population and two follow-up surveys among field workers and farmers.

[Assessment of three filters for respiratory function tests].

Several filters specific for respiratory function tests have been on the market for several years. Recommended by the manufacturers to avoid contaminating the equipment and thus improve patient safety, these filters require a considerable financial investment. We studied the passage of diluted blood into artificial saliva in a patient model simulating inspiration tests and rapid forced expiration to assess the retention capacity of three filters used for respiratory function tests: Multi SPIRO MI-90016 (MultiSPIRO), PF 30S (Pall Biomedical) and Spirobac (Dar.

Response of Photochemical Processes of Photosynthesis to Dinitrogen Fixation in Soybean.

Symbiotic N2 fixation activity brings about changes in the photochemical processes of photosynthesis in soybean (Glycine max L. Merr.).

Comparison of two extraction procedures for urinary organic acids prior to gas chromatography-mass spectrometry.

We have compared a new isolation procedure for urinary organic acids using strong anion-exchange columns with a solvent partition (ethyl acetate) method. Urinary samples from two healthy children and from nine children with organic acidurias were analysed by both procedures. Although the solid-phase extraction is more efficient for polyhydroxy acids, some polar acids, and some glycine derivatives, clinically important compounds such as oxalic, methylcitric, pyruvic, glyoxylic and 2-ketoglutaric acids, are not recovered or are only poorly recovered.

Divergent selection for dinitrogen fixation and yield in soybean.

Nitrogen fixation is generally considered to be a major parameter of productivity in soybean (Glycine max). The aim of the investigations reported here was to analyse the genetic behaviour of this trait in view of its possible use as an indirect criterion of selection for productivity. Divergent selection for nitrogen fixation rate was carried out on F2 populations obtained from crosses between high-yielding cultivars that are well adapted to French climatic conditions.

Role of D-genome chromosomes in photosynthesis expression in wheats.

The role of D-genome chromosomes in the expression of net photosynthesis in wheats was analysed with the nullitetrasomic and ditelosomic lines of the bread wheat cultivar 'Chinese Spring'. The two arms of chromosome 3 D and the short arm of chromosome 6 D control major mechanisms of photosynthesis. The effect of chromosome 6 D can be thoroughly compensated by that of its homoeologues of genomes A or B, contrary to what can be observed for chromosome 3 D.

Effect of the D genome and of selection on photosynthesis in wheat.

Photosynthesis and transpiration in wheats and in their progenitors were analyzed in relation to their genome, ploidy and selection. The values of these parameters markedly depend on a specific effect of the D genome and on leaf enlargement in the course of evolution in wheats. Leaf enlargement has had a marked effect on photosynthesis in the genotypes that are devoid of the D genome; in addition, their photosynthetic capacity is greater in forms with lower leaf area.

[Gamma-ray angioencephalography and computerized tomography of the brain in tumoral pathology. Comparative results].

Gamma-ray angioencephalography and computerized tomography (CT) were used to explore 151 patients with suspected intracranial tumour. The reliability of each method for the aetiological, topographical and pathological diagnosis was evaluated. The results obtained showed that the two methods correlated well and supplemented each other, bringing the proportion of positive diagnosis of intracranial tumour to more than 90%.