Depigmenting action of a nanoemulsion containing heartwood extract of Artocarpus incisus on UVB-induced hyperpigmentation in C57BL/6 mice.

Melasma hyperpigmentation is an acquired disorder predominantly affecting the female population. The present study was conducted to determine the potential of a botanical extract to reduce observable hyperpigmentation. The extract from heartwood of Artocarpus incisus was formulated into nanoemulsions, and the depigmenting efficacy of the formulated nanoemulsion was determined in vivo.

Evaluation of the effect of Thai breadfruit's heartwood extract on melanogenesis-inhibitory and antioxidation activities.

The aim of this study was to clarify the melanogenesis-inhibitory and antioxidant activity of Thai breadfruit's heartwood extract for application as a skin-lightening agent. The heartwood of breadfruit (Artocarpus incisus ) grown in Phitsanulok Province, Thailand, was extracted by using diethyl ether or methanol. The amount of artocarpin, a major component of A.